Susan Dina Ghiassian
Susan Dina Ghiassian
Scipher Medicine
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A proteome-scale map of the human interactome network
T Rolland, M Taşan, B Charloteaux, SJ Pevzner, Q Zhong, N Sahni, S Yi, ...
Cell 159 (5), 1212-1226, 2014
11112014
Uncovering disease-disease relationships through the incomplete interactome
J Menche, A Sharma, M Kitsak, SD Ghiassian, M Vidal, J Loscalzo, ...
Science 347 (6224), 2015
9722015
A DIseAse MOdule Detection (DIAMOnD) algorithm derived from a systematic analysis of connectivity patterns of disease proteins in the human interactome
SD Ghiassian, J Menche, AL Barabási
PLoS computational biology 11 (4), e1004120, 2015
2512015
A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma
A Sharma, J Menche, CC Huang, T Ort, X Zhou, M Kitsak, N Sahni, ...
Human molecular genetics 24 (11), 3005-3020, 2015
1462015
Network medicine framework for identifying drug-repurposing opportunities for COVID-19
DM Gysi, Í Do Valle, M Zitnik, A Ameli, X Gan, O Varol, SD Ghiassian, ...
Proceedings of the National Academy of Sciences 118 (19), 2021
1182021
Tissue specificity of human disease module
M Kitsak, A Sharma, J Menche, E Guney, SD Ghiassian, J Loscalzo, ...
Scientific reports 6 (1), 1-12, 2016
732016
Endophenotype network models: common core of complex diseases
SD Ghiassian, J Menche, DI Chasman, F Giulianini, R Wang, P Ricchiuto, ...
Scientific reports 6 (1), 1-13, 2016
602016
Clinical validation of a blood-based predictive test for stratification of response to tumor necrosis factor inhibitor therapies in rheumatoid arthritis patients
T Mellors, JB Withers, A Ameli, A Jones, M Wang, L Zhang, HN Sanchez, ...
Network and Systems Medicine 3 (1), 91-104, 2020
122020
Network medicine framework for identifying drug repurposing opportunities for COVID-19. ArXiv
DM Gysi, Í Do Valle, M Zitnik, A Ameli, X Gan, O Varol, H Sanchez, ...
arXiv preprint arXiv:2004.07229, 2020
112020
Network Medicine Framework for Identifying Drug Repurposing Opportunities for COVID-19. arXiv. 2020
DM Gysi, ÍD Valle, M Zitnik, A Ameli, X Gan, O Varol, H Sanchez, ...
arXiv preprint arXiv:2004.07229, 2004
92004
A Molecular Signature Response Classifier to Predict Inadequate Response to Tumor Necrosis Factor-α Inhibitors: The NETWORK-004 Prospective Observational Study
S Cohen, AF Wells, JR Curtis, R Dhar, T Mellors, L Zhang, JB Withers, ...
Rheumatology and Therapy, 1-18, 2021
22021
A systems-based method to repurpose marketed therapeutics for antiviral use: a SARS-CoV-2 case study
M Wang, JB Withers, P Ricchiuto, I Voitalov, M McAnally, HN Sanchez, ...
Life science alliance 4 (5), 2021
12021
Network Medicine: A Network-based Approach to Human Diseases
SD Ghiassian
Northeastern University, 2015
12015
Developing classifiers for stratifying patients
SD Ghiassian, TR Mellors, M Santolini, A Ameli, N Schoenbrunner, ...
US Patent App. 17/315,580, 2021
2021
Network-based response module comprised of gene expression biomarkers predicts response to infliximab at treatment initiation in ulcerative colitis
SD Ghiassian, JB Withers, M Santolini, A Saleh, VR Akmaev
Translational Research, 2021
2021
NHLBI-CMREF Workshop Report on Pulmonary Vascular Disease Classification: JACC State-of-the-Art Review
WM Oldham, AR Hemnes, MA Aldred, J Barnard, EL Brittain, SY Chan, ...
Journal of the American College of Cardiology 77 (16), 2040-2052, 2021
2021
Methods and systems for predicting response to anti-tnf therapies
KJ Johnson, SD Ghiassian
US Patent App. 16/394,046, 2019
2019
System and Methods for Disease Module Detection
S Ghiassian, J Menche, A Sharma, AL Barabasi
US Patent App. 15/913,826, 2019
2019
PRISM-RA: A Personalized Medicine Test That Accurately Predicts Rheumatoid Arthritis Patients Who Will Not Respond Adequately to Tumor Necrosis Factor Inhibitors
K Johnson
2018 ACR/ARHP Annual Meeting, 2018
2018
System and Methods for Disease Module Detection
S Ghiassian, J Menche, A Sharma, AL Barabasi
US Patent App. 15/023,582, 2016
2016
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Artículos 1–20