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Cynthia Hawkins
Cynthia Hawkins
Neuropathologist, Cell Biology Program, The Hospital for Sick Children, The University of Toronto
Dirección de correo verificada de sickkids.ca - Página principal
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Identification of human brain tumour initiating cells
SK Singh, C Hawkins, ID Clarke, JA Squire, J Bayani, T Hide, ...
nature 432 (7015), 396-401, 2004
91812004
Identification of a cancer stem cell in human brain tumors
SK Singh, ID Clarke, M Terasaki, VE Bonn, C Hawkins, J Squire, PB Dirks
Cancer research 63 (18), 5821-5828, 2003
68632003
The 2021 WHO classification of tumors of the central nervous system: a summary
DN Louis, A Perry, P Wesseling, DJ Brat, IA Cree, D Figarella-Branger, ...
Neuro-oncology 23 (8), 1231-1251, 2021
56322021
Medulloblastoma comprises four distinct molecular variants
PA Northcott, A Korshunov, H Witt, T Hielscher, CG Eberhart, S Mack, ...
Journal of clinical oncology 29 (11), 1408, 2011
15062011
Intertumoral heterogeneity within medulloblastoma subgroups
FMG Cavalli, M Remke, L Rampasek, J Peacock, DJH Shih, B Luu, ...
Cancer cell 31 (6), 737-754. e6, 2017
10332017
K27M mutation in histone H3. 3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
DA Khuong-Quang, P Buczkowicz, P Rakopoulos, XY Liu, ...
Acta neuropathologica 124, 439-447, 2012
9552012
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ...
Nature 488 (7409), 49-56, 2012
9542012
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations
T Rausch, DTW Jones, M Zapatka, AM Stütz, T Zichner, J Weischenfeldt, ...
Cell 148 (1), 59-71, 2012
9132012
Integrated molecular meta-analysis of 1,000 pediatric high-grade and diffuse intrinsic pontine glioma
A Mackay, A Burford, D Carvalho, E Izquierdo, J Fazal-Salom, KR Taylor, ...
Cancer cell 32 (4), 520-537. e5, 2017
8372017
Immune checkpoint inhibition for hypermutant glioblastoma multiforme resulting from germline biallelic mismatch repair deficiency
E Bouffet, V Larouche, BB Campbell, D Merico, R De Borja, M Aronson, ...
Journal of clinical oncology 34 (19), 2206-2211, 2016
8172016
Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme
A Wolf, S Agnihotri, J Micallef, J Mukherjee, N Sabha, R Cairns, ...
Journal of Experimental Medicine 208 (2), 313-326, 2011
8072011
Comprehensive analysis of hypermutation in human cancer
BB Campbell, N Light, D Fabrizio, M Zatzman, F Fuligni, R de Borja, ...
Cell 171 (5), 1042-1056. e10, 2017
6832017
I nternational S ociety of N europathology‐H aarlem C onsensus G uidelines for N ervous S ystem T umor C lassification and G rading
DN Louis, A Perry, P Burger, DW Ellison, G Reifenberger, A von Deimling, ...
Brain pathology 24 (5), 429-435, 2014
6642014
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ...
Nature 506 (7489), 445-450, 2014
6292014
Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations
P Buczkowicz, C Hoeman, P Rakopoulos, S Pajovic, L Letourneau, ...
Nature genetics 46 (5), 451-456, 2014
6182014
Functionally defined therapeutic targets in diffuse intrinsic pontine glioma
CS Grasso, Y Tang, N Truffaux, NE Berlow, L Liu, MA Debily, MJ Quist, ...
Nature medicine 21 (6), 555-559, 2015
6122015
Functionally defined therapeutic targets in diffuse intrinsic pontine glioma
CS Grasso, Y Tang, N Truffaux, NE Berlow, L Liu, MA Debily, MJ Quist, ...
Nature medicine 21 (6), 555-559, 2015
6112015
Paediatric and adult glioblastoma: multiform (epi) genomic culprits emerge
D Sturm, S Bender, DTW Jones, P Lichter, J Grill, O Becher, C Hawkins, ...
Nature Reviews Cancer 14 (2), 92-107, 2014
6032014
Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma
H Witt, SC Mack, M Ryzhova, S Bender, M Sill, R Isserlin, A Benner, ...
Cancer cell 20 (2), 143-157, 2011
5562011
Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma
N Zhukova, V Ramaswamy, M Remke, E Pfaff, DJH Shih, DC Martin, ...
Journal of Clinical Oncology 31 (23), 2927, 2013
5032013
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Artículos 1–20