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Guan Junhong
Guan Junhong
Dirección de correo verificada de utsouthwestern.edu
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DNA sensing in mismatch repair-deficient tumor cells is essential for anti-tumor immunity
C Lu, J Guan, S Lu, Q Jin, B Rousseau, T Lu, D Stephens, H Zhang, J Zhu, ...
Cancer cell 39 (1), 96-108. e6, 2021
1772021
MLH1 deficiency-triggered DNA hyperexcision by exonuclease 1 activates the cGAS-STING pathway
J Guan, C Lu, Q Jin, H Lu, X Chen, L Tian, Y Zhang, J Ortega, J Zhang, ...
Cancer cell 39 (1), 109-121. e5, 2021
1292021
RNF168-mediated H2A neddylation antagonizes ubiquitylation of H2A and regulates DNA damage repair
T Li, J Guan, Z Huang, X Hu, X Zheng
Journal of cell science 127 (10), 2238-2248, 2014
752014
hCINAP is a novel regulator of ribosomal protein-HDM2-p53 pathway by controlling NEDDylation of ribosomal protein S14
J Zhang, D Bai, X Ma, J Guan, X Zheng
Oncogene 33 (2), 246-254, 2014
582014
HSCARG downregulates NF-κB signaling by interacting with USP7 and inhibiting NEMO ubiquitination
T Li, J Guan, S Li, X Zhang, X Zheng
Cell death & disease 5 (5), e1229-e1229, 2014
352014
NEDDylation antagonizes ubiquitination of proliferating cell nuclear antigen and regulates the recruitment of polymerase η in response to oxidative DNA damage
J Guan, S Yu, X Zheng
Protein & cell 9 (4), 365-379, 2018
282018
MyD88 NEDDylation negatively regulates MyD88-dependent NF-κB signaling through antagonizing its ubiquitination
F Yan, J Guan, Y Peng, X Zheng
Biochemical and biophysical research communications 482 (4), 632-637, 2017
172017
Targeting UBE2T potentiates gemcitabine efficacy in pancreatic cancer by regulating pyrimidine metabolism and replication stress
X Jiang, Y Ma, T Wang, H Zhou, K Wang, W Shi, L Qin, J Guan, L Li, ...
Gastroenterology 164 (7), 1232-1247, 2023
132023
The herpes simplex virus 1 UL36USP deubiquitinase suppresses DNA repair in host cells via deubiquitination of proliferating cell nuclear antigen
X Dong, J Guan, C Zheng, X Zheng
Journal of Biological Chemistry 292 (20), 8472-8483, 2017
132017
A CRM 1‐Dependent Nuclear Export Signal Controls Nucleocytoplasmic Translocation of HSCARG, Which Regulates NF‐κB Activity
M Zhang, B Hu, T Li, Y Peng, J Guan, S Lai, X Zheng
Traffic 13 (6), 790-799, 2012
132012
NEDDylation regulates RAD18 ubiquitination and localization in response to oxidative DNA damage
J Guan, X Zheng
Biochemical and biophysical research communications 508 (4), 1240-1244, 2019
92019
DNA-PKcs-dependent phosphorylation of RECQL4 promotes NHEJ by stabilizing the NHEJ machinery at DNA double-strand breaks
H Lu, J Guan, SY Wang, GM Li, VA Bohr, AJ Davis
Nucleic acids research 50 (10), 5635-5651, 2022
72022
DNA mismatch repair in cancer immunotherapy
J Guan, GM Li
NAR cancer 5 (3), zcad031, 2023
62023
PICH Activates Cyclin A1 Transcription to Drive S-Phase Progression and Chemoresistance in Gastric Cancer
H Ye, W Shi, J Yang, L Wang, X Jiang, H Zhao, L Qin, J Qin, L Li, W Cai, ...
Cancer Research 83 (22), 3767-3782, 2023
32023
Mutant huntingtin protein induces MLH1 degradation, DNA hyperexcision, and cGAS–STING-dependent apoptosis
X Sun, L Liu, C Wu, X Li, J Guo, J Zhang, J Guan, N Wang, L Gu, ...
Proceedings of the National Academy of Sciences 121 (13), e2313652121, 2024
2024
RNF168-mediated H2A neddylation antagonizes its ubiquitinationand regulates DNA damage repair
J Guan, T Li, X Zheng
中国生物化学与分子生物学会第十一次会员代表大会暨 2014 年全国学术会议论文集 …, 2014
2014
Critical Reviews and Perspectives DNA mismatch repair in cancer immunotherapy
J Guan, GM Li
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Artículos 1–17