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Saman Honarnejad
Saman Honarnejad
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Metrics other than potency reveal systematic variation in responses to cancer drugs
M Fallahi-Sichani, S Honarnejad, LM Heiser, JW Gray, PK Sorger
Nature chemical biology 9 (11), 708-714, 2013
3522013
Hit discovery for public target programs in the european lead factory: experiences and output from assay development and ultra-high-throughput screening
S Honarnejad, S van Boeckel, H van den Hurk, S van Helden
SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (2), 192-204, 2021
112021
Ultra-high-throughput Ca2+ assay in platelets to distinguish ITAM-linked and G-protein-coupled receptor activation
DI Fernández, I Provenzale, HYF Cheung, J van Groningen, ...
Iscience 25 (1), 2022
72022
Replenishing the malaria drug discovery pipeline: screening and hit evaluation of the MMV Hit Generation Library 1 (HGL1) against asexual blood stage Plasmodium falciparum …
KJ Dechering, M Timmerman, K Rensen, KMJ Koolen, S Honarnejad, ...
SLAS Discovery 27 (6), 337-348, 2022
62022
IMI European Lead Factory—democratizing access to high-throughput screening
PS Jones, S Boucharens, SP McElroy, A Morrison, S Honarnejad, ...
Nature Reviews Drug Discovery 21 (4), 245-246, 2022
22022
The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds
J Gising, S Honarnejad, M Bras, GL Baillie, SP McElroy, PS Jones, ...
International Journal of Molecular Sciences 25 (7), 4084, 2024
2024
Ultra-high throughput-based screening for the discovery of antiplatelet drugs affecting receptor dependent calcium signaling dynamics
DI Fernández, S Troitiño, V Sobota, BME Tullemans, J Zou, ...
Scientific Reports 14 (1), 6229, 2024
2024
A high-throughput screening strategy identifies adenosine 5'-monophosphate as a novel enhancing molecule of the cardio-protective enzyme 5-oxoprolinase (OPLAH)
A Esquivel-Gaytan, N Bomer, R Bartolo, KF Arevalo-Gomez, ...
European Heart Journal 44 (Supplement_2), ehad655. 3130, 2023
2023
SLAS Discovery
KJ Dechering, M Timmerman, K Rensen, KMJ Koolen, S Honarnejad, ...
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