| Aminergic and peptidergic pathways in the nervous system with special reference to the hypothalamus T Hökfelt, R Elde, K Fuxe, O Johansson, A Ljungdahl, M Goldstein, R Luft, ... Research publications-Association for Research in Nervous and Mental Disease …, 1978 | 368 | 1978 |
| Seizures and neurodegeneration induced by 4-aminopyridine in rat hippocampus in vivo: role of glutamate-and GABA-mediated neurotransmission and of ion channels F Pena, R Tapia Neuroscience 101 (3), 547-561, 2000 | 230 | 2000 |
| Accumulation of extracellular glutamate by inhibition of its uptake is not sufficient for inducing neuronal damage: an in vivo microdialysis study L Massieu, A Morales‐Villagrán, R Tapia Journal of neurochemistry 64 (5), 2262-2272, 1995 | 189 | 1995 |
| β‐Amyloid peptide fragment 25–35 potentiates the calcium‐dependent release of excitatory amino acids from depolarized hippocampal slices C Arias, I Arrieta, R Tapia Journal of neuroscience research 41 (4), 561-566, 1995 | 139 | 1995 |
| Effect of 4-aminopyridine on transmitter release in synaptosomes R Tapia Brain research 250 (2), 291-299, 1982 | 130 | 1982 |
| Glutamate excitotoxicity and therapeutic targets for amyotrophic lateral sclerosis JC Corona, LB Tovar-y-Romo, R Tapia Expert opinion on therapeutic targets 11 (11), 1415-1428, 2007 | 115 | 2007 |
| Relationships among seizures, extracellular amino acid changes, and neurodegeneration induced by 4‐aminopyridine in rat hippocampus: A microdialysis and electroencephalographic … F Peña, R Tapia Journal of Neurochemistry 72 (5), 2006-2014, 1999 | 114 | 1999 |
| Demonstration of central gamma-aminobutyrate-containing nerve terminals by means of antibodies against glutamate decarboxylase. LD Possani, R Tapia, L Teran, R Palacios, K Fuxe, T Hökfelt, A Ljungdahl Neuroscience 6 (5), 875-895, 1981 | 108 | 1981 |
| Biochemical pharmacology of GABA in CNS R Tapia Amino Acid Neurotransmitters, 1-58, 1975 | 106 | 1975 |
| Trophic factors as modulators of motor neuron physiology and survival: implications for ALS therapy LB Tovar-y-Romo, UN Ramírez-Jarquín, R Lazo-Gómez, R Tapia Frontiers in cellular neuroscience 8, 61, 2014 | 105 | 2014 |
| Review article On the relationship between extracellular glutamate, hyperexcitation and neurodegeneration, in vivo R Tapia, L Medina-Ceja, F Pena Neurochemistry international 34 (1), 23-31, 1999 | 94 | 1999 |
| Glutamine and glutamate as precursors of the releasable pool of GABA in brain cortex slices R Tapia, RM Gonzalez Neuroscience Letters 10 (1-2), 165-169, 1978 | 91 | 1978 |
| Glutamate uptake impairment and neuronal damage in young and aged rats in vivo L Massieu, R Tapia Journal of neurochemistry 69 (3), 1151-1160, 1997 | 87 | 1997 |
| Preferential stimulation of glutamate release by 4-aminopyridine in rat striatum in vivo A Morales-Villagrán, R Tapia Neurochemistry International 28 (1), 35-40, 1996 | 87 | 1996 |
| Inhibition by ruthenium red of the calcium-dependent release of [3H] GABA in synaptosomal fractions R Tapia, G Meza-Ruíz Brain Research 126 (1), 160-166, 1977 | 87 | 1977 |
| Ruthenium red as a tool to study calcium channels, neuronal death and the function of neural pathways R Tapia, I Velasco Neurochemistry international 30 (2), 137-147, 1997 | 84 | 1997 |
| Demonstration of central γ-aminobutyrate-containing nerve terminals by means of antibodies against glutamate decarboxylase M Perez De La Mora, LD Possani, R Tapia, L Teran, R Palacios, K Fuxe, ... Neuroscience 6 (875), 1981 | 82 | 1981 |
| Ca2+-permeable AMPA receptors and intracellular Ca2+ determine motoneuron vulnerability in rat spinal cord in vivo JC Corona, R Tapia Neuropharmacology 52 (5), 1219-1228, 2007 | 81 | 2007 |
| Evidence for a role of glutamate decarboxylase activity as a regulatory mechanism of cerebral excitability R Tapia, ME Sandoval, P Contreras Journal of Neurochemistry 24 (6), 1283-1285, 1975 | 81 | 1975 |
| Studies on different types of dopamine nerve terminals in the forebrain and their possible interactions with hormones and with neurons containing GABA, glutamate, and opioid … K Fuxe, K Andersson, R Schwarcz, LF Agnati, MP de La Mora, T Hökfelt, ... Advances in neurology 24, 199-215, 1979 | 76 | 1979 |
