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Igor  Pogribny
Igor Pogribny
NCTR/FDA
Dirección de correo verificada de fda.hhs.gov
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Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin
O Kovalchuk, J Filkowski, J Meservy, Y Ilnytskyy, VP Tryndyak, ...
Molecular cancer therapeutics 7 (7), 2152-2159, 2008
8032008
Increase in plasma homocysteine associated with parallel increases in plasma S-adenosylhomocysteine and lymphocyte DNA hypomethylation
P Yi, S Melnyk, M Pogribna, IP Pogribny, RJ Hine, SJ James
Journal of Biological Chemistry 275 (38), 29318-29323, 2000
8012000
Downregulation of miR‐122 in the rodent and human hepatocellular carcinomas
H Kutay, S Bai, J Datta, T Motiwala, I Pogribny, W Frankel, ST Jacob, ...
Journal of cellular biochemistry 99 (3), 671-678, 2006
7962006
Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition
Z Chen, AC Karaplis, SL Ackerman, IP Pogribny, S Melnyk, ...
Human molecular genetics 10 (5), 433-444, 2001
7712001
Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome
SJ James, M Pogribna, IP Pogribny, S Melnyk, RJ Hine, JB Gibson, P Yi, ...
The American journal of clinical nutrition 70 (4), 495-501, 1999
6921999
Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women
RA Jacob, DM Gretz, PC Taylor, SJ James, IP Pogribny, BJ Miller, ...
The Journal of nutrition 128 (7), 1204-1212, 1998
6301998
Elevation in S-adenosylhomocysteine and DNA hypomethylation: potential epigenetic mechanism for homocysteine-related pathology
SJ James, S Melnyk, M Pogribna, IP Pogribny, MA Caudill
The Journal of nutrition 132 (8), 2361S-2366S, 2002
4392002
Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene
YI Kim, IP Pogribny, AG Basnakian, JW Miller, J Selhub, SJ James, ...
The American journal of clinical nutrition 65 (1), 46-52, 1997
4201997
Alterations of microRNAs and their targets are associated with acquired resistance of MCF‐7 breast cancer cells to cisplatin
IP Pogribny, JN Filkowski, VP Tryndyak, A Golubov, SI Shpyleva, ...
International journal of cancer 127 (8), 1785-1794, 2010
4142010
Breaks in Genomic DNA and within the p53 Gene Are Associated with Hypomethylation in Livers of Folate/methyl-deficient Rats
IP Pogribny, AG Basnakian, BJ Miller, NG Lopatina, LA Poirier, SJ James
Cancer research 55 (9), 1894-1901, 1995
3721995
Transgenerational changes in the genome stability and methylation in pathogen-infected plants: (Virus-induced plant genome instability)
A Boyko, P Kathiria, FJ Zemp, Y Yao, I Pogribny, I Kovalchuk
Nucleic acids research 35 (5), 1714-1725, 2007
3682007
Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location
C Yauk, A Polyzos, A Rowan-Carroll, CM Somers, RW Godschalk, ...
Proceedings of the National Academy of Sciences 105 (2), 605-610, 2008
3552008
Intracellular S-adenosylhomocysteine concentrations predict global DNA hypomethylation in tissues of methyl-deficient cystathionine β-synthase heterozygous mice
MA Caudill, JC Wang, S Melnyk, IP Pogribny, MD Collins, ...
The Journal of nutrition 131 (11), 2811-2818, 2001
3462001
Homocysteine metabolism in children with Down syndrome: in vitro modulation
M Pogribna, S Melnyk, I Pogribny, A Chango, P Yi, SJ James
The American Journal of Human Genetics 69 (1), 88-95, 2001
3292001
E‐cadherin transcriptional down‐regulation by epigenetic and microRNA‐200 family alterations is related to mesenchymal and drug‐resistant phenotypes in human breast cancer cells
VP Tryndyak, FA Beland, IP Pogribny
International journal of cancer 126 (11), 2575-2583, 2010
2752010
Measurement of Plasma and Intracellular S-Adenosylmethionine and S-Adenosylhomocysteine Utilizing Coulometric Electrochemical Detection: Alterations with …
S Melnyk, M Pogribna, IP Pogribny, P Yi, SJ James
Clinical chemistry 46 (2), 265-272, 2000
2752000
Irradiation induces DNA damage and modulates epigenetic effectors in distant bystander tissue in vivo
I Koturbash, RE Rugo, CA Hendricks, J Loree, B Thibault, K Kutanzi, ...
Oncogene 25 (31), 4267-4275, 2006
2662006
Genome hypermethylation in Pinus silvestris of Chernobyl—a mechanism for radiation adaptation?
O Kovalchuk, P Burke, A Arkhipov, N Kuchma, SJ James, I Kovalchuk, ...
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 529 (1 …, 2003
2612003
A new HPLC method for the simultaneous determination of oxidized and reduced plasma aminothiols using coulometric electrochemical detection
S Melnyk, M Pogribna, I Pogribny, RJ Hine, SJ James
The Journal of nutritional biochemistry 10 (8), 490-497, 1999
2601999
DNA hypomethylation in the origin and pathogenesis of human diseases
IP Pogribny, FA Beland
Cellular and Molecular Life Sciences 66, 2249-2261, 2009
2552009
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Artículos 1–20