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Lydia Teboul
Lydia Teboul
Mary Lyon Centre - MRC Harwell
Dirección de correo verificada de har.mrc.ac.uk
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Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR
M Haeussler, K Schönig, H Eckert, A Eschstruth, J Mianné, JB Renaud, ...
Genome biology 17, 1-12, 2016
16292016
High-throughput discovery of novel developmental phenotypes
ME Dickinson, AM Flenniken, X Ji, L Teboul, MD Wong, JK White, ...
Nature 537 (7621), 508-514, 2016
10802016
NAADP mobilizes calcium from acidic organelles through two-pore channels
PJ Calcraft, M Ruas, Z Pan, X Cheng, A Arredouani, X Hao, J Tang, ...
Nature 459 (7246), 596-600, 2009
8782009
Overexpression of Fto leads to increased food intake and results in obesity
C Church, L Moir, F McMurray, C Girard, GT Banks, L Teboul, S Wells, ...
Nature genetics 42 (12), 1086-1092, 2010
8502010
p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex
L Nguyen, A Besson, JIT Heng, C Schuurmans, L Teboul, C Parras, ...
Genes & development 20 (11), 1511-1524, 2006
4072006
The mammalian gene function resource: the International Knockout Mouse Consortium
A Bradley, K Anastassiadis, A Ayadi, JF Battey, C Bell, MC Birling, ...
Mammalian genome 23, 580-586, 2012
3242012
Thiazolidinediones and fatty acids convert myogenic cells into adipose-like cells
L Teboul, D Gaillard, L Staccini, H Inadera, EZ Amri, PA Grimaldi
Journal of Biological Chemistry 270 (47), 28183-28187, 1995
2811995
Prevalence of sexual dimorphism in mammalian phenotypic traits
NA Karp, J Mason, AL Beaudet, Y Benjamini, L Bower, RE Braun, ...
Nature communications 8 (1), 15475, 2017
2412017
Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.
Meehan
2312017
Evidence for a common mechanism of action for fatty acids and thiazolidinedione antidiabetic agents on gene expression in preadipose cells.
A Ibrahimi, L Teboul, D Gaillard, EZ Amri, G Ailhaud, P Young, ...
Molecular pharmacology 46 (6), 1070-1076, 1994
1851994
Adult Onset Global Loss of the Fto Gene Alters Body Composition and Metabolism in the Mouse
F McMurray, CD Church, R Larder, G Nicholson, S Wells, L Teboul, ...
PLoS genetics 9 (1), e1003166, 2013
1712013
Mice with endogenous TDP‐43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis
P Fratta, P Sivakumar, J Humphrey, K Lo, T Ricketts, H Oliveira, ...
The EMBO journal 37 (11), e98684, 2018
1592018
Mouse large-scale phenotyping initiatives: Overview of the European mouse disease clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project
A Ayadi, MC Birling, J Bottomley, J Bussell, H Fuchs, M Fray, ...
Mammalian Genome 23, 600-610, 2012
1542012
Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics
M Hrabě de Angelis, G Nicholson, M Selloum, JK White, H Morgan, ...
Nature genetics 47 (9), 969-978, 2015
1472015
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction
MR Bowl, MM Simon, NJ Ingham, S Greenaway, L Santos, H Cater, ...
Nature communications 8 (1), 886, 2017
1372017
Correction of the auditory phenotype in C57BL/6N mice via CRISPR/Cas9-mediated homology directed repair
J Mianné, L Chessum, S Kumar, C Aguilar, G Codner, M Hutchison, ...
Genome medicine 8, 1-12, 2016
1282016
Microhomologies are prevalent at Cas9-induced larger deletions
DDG Owens, A Caulder, V Frontera, JR Harman, AJ Allan, A Bucakci, ...
Nucleic acids research 47 (14), 7402-7417, 2019
1202019
Uncoupling Antisense-Mediated Silencing and DNA Methylation in the Imprinted Gnas Cluster
CM Williamson, ST Ball, C Dawson, S Mehta, CV Beechey, M Fray, ...
PLoS genetics 7 (3), e1001347, 2011
1142011
TPC1 has two variant isoforms, and their removal has different effects on endo-lysosomal functions compared to loss of TPC2
M Ruas, KT Chuang, LC Davis, A Al-Douri, PW Tynan, R Tunn, L Teboul, ...
Molecular and cellular biology 34 (21), 3981-3992, 2014
1052014
Fatty acids regulate the expression of lipoprotein lipase gene and activity in preadipose and adipose cells
EZ AMRI, L TEBOUL, C VANNIER, PA GRIMALDI, G AILHAUD
Biochemical Journal 314 (2), 541-546, 1996
1001996
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Artículos 1–20