| Structure of human O-GlcNAc transferase and its complex with a peptide substrate MB Lazarus, Y Nam, J Jiang, P Sliz, S Walker Nature 469 (7331), 564-567, 2011 | 488 | 2011 |
| Imaging peptidoglycan biosynthesis in Bacillus subtilis with fluorescent antibiotics K Tiyanont, T Doan, MB Lazarus, X Fang, DZ Rudner, S Walker Proceedings of the National Academy of Sciences 103 (29), 11033-11038, 2006 | 296 | 2006 |
| A small molecule that inhibits OGT activity in cells RF Ortiz-Meoz, J Jiang, MB Lazarus, M Orman, J Janetzko, C Fan, ... ACS chemical biology 10 (6), 1392-1397, 2015 | 237 | 2015 |
| HCF-1 is cleaved in the active site of O-GlcNAc transferase MB Lazarus, J Jiang, V Kapuria, T Bhuiyan, J Janetzko, WF Zandberg, ... Science 342 (6163), 1235-1239, 2013 | 206 | 2013 |
| Structural snapshots of the reaction coordinate for O-GlcNAc transferase MB Lazarus, J Jiang, TM Gloster, WF Zandberg, GE Whitworth, ... Nature chemical biology 8 (12), 966-968, 2012 | 189 | 2012 |
| Structure of the human autophagy initiating kinase ULK1 in complex with potent inhibitors MB Lazarus, CJ Novotny, KM Shokat ACS chemical biology 10 (1), 257-261, 2015 | 159 | 2015 |
| Paclitaxel induces calcium oscillations via an inositol 1, 4, 5-trisphosphate receptor and neuronal calcium sensor 1-dependent mechanism W Boehmerle, U Splittgerber, MB Lazarus, KM McKenzie, DG Johnston, ... Proceedings of the National Academy of Sciences 103 (48), 18356-18361, 2006 | 157 | 2006 |
| Structure-based evolution of low nanomolar O-GlcNAc transferase inhibitors SES Martin, ZW Tan, HM Itkonen, DY Duveau, JA Paulo, J Janetzko, ... Journal of the American Chemical Society 140 (42), 13542-13545, 2018 | 128 | 2018 |
| A neutral diphosphate mimic crosslinks the active site of human O-GlcNAc transferase J Jiang, MB Lazarus, L Pasquina, P Sliz, S Walker Nature chemical biology 8 (1), 72-77, 2012 | 123 | 2012 |
| Decoupling catalytic activity from biological function of the ATPase that powers lipopolysaccharide transport DJ Sherman, MB Lazarus, L Murphy, C Liu, S Walker, N Ruiz, D Kahne Proceedings of the National Academy of Sciences 111 (13), 4982-4987, 2014 | 112 | 2014 |
| The antibiotic novobiocin binds and activates the ATPase that powers lipopolysaccharide transport JM May, TW Owens, MD Mandler, BW Simpson, MB Lazarus, ... Journal of the American Chemical Society 139 (48), 17221-17224, 2017 | 87 | 2017 |
| Discovery and structure of a new inhibitor scaffold of the autophagy initiating kinase ULK1 MB Lazarus, KM Shokat Bioorganic & medicinal chemistry 23 (17), 5483-5488, 2015 | 66 | 2015 |
| Synthesis and biological validation of a harmine-based, central nervous system (CNS)-avoidant, selective, human β-cell regenerative dual-specificity tyrosine phosphorylation … K Kumar, P Wang, J Wilson, V Zlatanic, C Berrouet, S Khamrui, C Secor, ... Journal of medicinal chemistry 63 (6), 2986-3003, 2020 | 47 | 2020 |
| How the glycosyltransferase OGT catalyzes amide bond cleavage J Janetzko, SA Trauger, MB Lazarus, S Walker Nature chemical biology 12 (11), 899-901, 2016 | 35 | 2016 |
| Discovery of new substrates of the elongation factor-2 kinase suggests a broader role in the cellular nutrient response MB Lazarus, RS Levin, KM Shokat Cellular signalling 29, 78-83, 2017 | 22 | 2017 |
| High-resolution structure and inhibition of the schizophrenia-linked pseudokinase ULK4 S Khamrui, PMU Ung, C Secor, A Schlessinger, MB Lazarus Journal of the American Chemical Society 142 (1), 33-37, 2019 | 21 | 2019 |
| Inhibition and crystal structure of the human DHTKD1-thiamin diphosphate complex J Leandro, S Khamrui, H Wang, C Suebsuwong, NS Nemeria, K Huynh, ... ACS chemical biology 15 (8), 2041-2047, 2020 | 16 | 2020 |
| Simple secondary amines inhibit growth of gram-negative bacteria through highly selective binding to phenylalanyl-tRNA synthetase V Baidin, TW Owens, MB Lazarus, D Kahne Journal of the American Chemical Society 143 (2), 623-627, 2021 | 9 | 2021 |
| Structure–function analyses of the G729R 2-oxoadipate dehydrogenase genetic variant associated with a disorder of l-lysine metabolism X Zhang, NS Nemeria, J Leandro, S Houten, M Lazarus, G Gerfen, ... Journal of Biological Chemistry 295 (23), 8078-8095, 2020 | 9 | 2020 |
| Discovery and initial characterization of YloC, a novel endoribonuclease in Bacillus subtilis S Ingle, S Chhabra, J Chen, MB Lazarus, X Luo, DH Bechhofer RNA 28 (2), 227-238, 2022 | 6 | 2022 |
