| FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase J Guan, G Umapathy, Y Yamazaki, G Wolfstetter, P Mendoza, K Pfeifer, ... elife 4, e09811, 2015 | 155 | 2015 |
| Gene expression profiles in different stages of mouse spermatogenic cells during spermatogenesis Z Yu, R Guo, Y Ge, J Ma, J Guan, S Li, X Sun, S Xue, D Han Biology of Reproduction 69 (1), 37-47, 2003 | 136 | 2003 |
| The ALK inhibitor PF-06463922 is effective as a single agent in neuroblastoma driven by expression of ALK and MYCN J Guan, ER Tucker, H Wan, D Chand, LS Danielson, K Ruuth, A El Wakil, ... Disease models & mechanisms 9 (9), 941-952, 2016 | 98 | 2016 |
| ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells A Fadeev, P Mendoza-Garcia, U Irion, J Guan, K Pfeifer, S Wiessner, ... Proceedings of the National Academy of Sciences 115 (4), E630-E638, 2018 | 85 | 2018 |
| Stage‐specific and tissue‐specific expression characteristics of differentially expressed genes during mouse spermatogenesis R Guo, Z Yu, J Guan, Y Ge, J Ma, S Li, S Wang, S Xue, D Han Molecular Reproduction and Development: Incorporating Gamete Research 67 (3 …, 2004 | 74 | 2004 |
| Brigatinib, an anaplastic lymphoma kinase inhibitor, abrogates activity and growth in ALK-positive neuroblastoma cells, Drosophila and mice JT Siaw, H Wan, K Pfeifer, VM Rivera, J Guan, RH Palmer, B Hallberg Oncotarget 7 (20), 29011, 2016 | 61 | 2016 |
| Clinical response of the novel activating ALK-I1171T mutation in neuroblastoma to the ALK inhibitor ceritinib J Guan, S Fransson, JT Siaw, D Treis, J Van den Eynden, D Chand, ... Molecular Case Studies 4 (4), a002550, 2018 | 56 | 2018 |
| MEK inhibitor trametinib does not prevent the growth of anaplastic lymphoma kinase (ALK)–addicted neuroblastomas G Umapathy, J Guan, DE Gustafsson, N Javanmardi, D Cervantes-Madrid, ... Science signaling 10 (507), eaam7550, 2017 | 54 | 2017 |
| Cohesin protein SMC1 is a centrosomal protein J Guan, E Ekwurtzel, U Kvist, L Yuan Biochemical and biophysical research communications 372 (4), 761-764, 2008 | 51 | 2008 |
| Spatiotemporal association of DNAJB13 with the annulus during mouse sperm flagellum development J Guan, M Kinoshita, L Yuan BMC developmental biology 9, 1-9, 2009 | 50 | 2009 |
| ALK ligand ALKAL2 potentiates MYCN‐driven neuroblastoma in the absence of ALK mutation M Borenäs, G Umapathy, WY Lai, DE Lind, B Witek, J Guan, ... The EMBO journal 40 (3), e105784, 2021 | 43 | 2021 |
| Phosphoproteome and gene expression profiling of ALK inhibition in neuroblastoma cell lines reveals conserved oncogenic pathways J Van den Eynden, G Umapathy, A Ashouri, D Cervantes-Madrid, ... Science signaling 11 (557), eaar5680, 2018 | 40 | 2018 |
| A heat‐shock protein 40, DNAJB13, is an axoneme‐associated component in mouse spermatozoa J Guan, L Yuan Molecular reproduction and development 75 (9), 1379-1386, 2008 | 37 | 2008 |
| DNAJB13 is a radial spoke protein of mouse ‘9+ 2’axoneme J Guan, E Ekwurtzel, U Kvist, K Hultenby, L Yuan Reproduction in domestic animals 45 (6), 992-996, 2010 | 23 | 2010 |
| Anaplastic lymphoma kinase L1198F and G1201E mutations identified in anaplastic thyroid cancer patients are not ligand-independent J Guan, G Wolfstetter, J Siaw, D Chand, F Hugosson, RH Palmer, ... Oncotarget 8 (7), 11566, 2017 | 21 | 2017 |
| Chromosome Imbalances in Neuroblastoma—Recent Molecular Insight into Chromosome 1p-deletion, 2p-gain, and 11q-deletion Identifies New Friends and Foes for the Future J Guan, B Hallberg, RH Palmer Cancers 13 (23), 5897, 2021 | 18 | 2021 |
| Novel mechanisms of ALK activation revealed by analysis of the Y1278S neuroblastoma mutation J Guan, Y Yamazaki, D Chand, JR Van Dijk, K Ruuth, RH Palmer, ... Cancers 9 (11), 149, 2017 | 18 | 2017 |
| BioID-screening identifies PEAK1 and SHP2 as components of the ALK proximitome in neuroblastoma cells E Uckun, JT Siaw, J Guan, V Anthonydhason, J Fuchs, G Wolfstetter, ... Journal of Molecular Biology 433 (19), 167158, 2021 | 14 | 2021 |
| Sustained response to entrectinib in an infant with a germline ALKAL2 variant and refractory metastatic neuroblastoma with chromosomal 2p gain and anaplastic lymphoma kinase … D Treis, G Umapathy, S Fransson, J Guan, P Mendoza-García, JT Siaw, ... JCO precision oncology 6, e2100271, 2022 | 12 | 2022 |
| Loss of ret promotes mesenchymal identity in neuroblastoma cells JT Siaw, JL Gabre, E Uçkun, M Vigny, W Zhang, J Van den Eynden, ... Cancers 13 (8), 1909, 2021 | 12 | 2021 |
