Seung P Kwak
Seung P Kwak
CHDI Foundation Inc.
Dirección de correo verificada de
Citado por
Citado por
Identification of genetic factors that modify clinical onset of Huntington’s disease
JM Lee, VC Wheeler, MJ Chao, JPG Vonsattel, RM Pinto, D Lucente, ...
Cell 162 (3), 516-526, 2015
Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology
Y Kim, JY Sung, I Ceglia, KW Lee, JH Ahn, JM Halford, AM Kim, SP Kwak, ...
Nature 442 (7104), 814-817, 2006
Integrated genomics and proteomics define huntingtin CAG length–dependent networks in mice
P Langfelder, JP Cantle, D Chatzopoulou, N Wang, F Gao, I Al-Ramahi, ...
Nature neuroscience 19 (4), 623-633, 2016
Corticosteroids regulate brain hippocampal 5-HT1A receptor mRNA expression
DT Chalmers, SP Kwak, A Mansour, H Akil, SJ Watson
Journal of Neuroscience 13 (3), 914-923, 1993
CAG repeat not polyglutamine length determines timing of Huntington’s disease onset
JM Lee, K Correia, J Loupe, KH Kim, D Barker, EP Hong, MJ Chao, ...
Cell 178 (4), 887-900. e14, 2019
Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels
S Horvath, P Langfelder, S Kwak, J Aaronson, J Rosinski, TF Vogt, ...
Aging (Albany NY) 8 (7), 1485, 2016
Matrix metalloproteinases are modifiers of huntingtin proteolysis and toxicity in Huntington's disease
JP Miller, J Holcomb, I Al-Ramahi, M De Haro, J Gafni, N Zhang, E Kim, ...
Neuron 67 (2), 199-212, 2010
Isolation and characterization of a human dual specificity protein-tyrosine phosphatase gene.
SP Kwak, DJ Hakes, KJ Martell, JE Dixon
Journal of Biological Chemistry 269 (5), 3596-3604, 1994
Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington’s disease
B Zeitler, S Froelich, K Marlen, DA Shivak, Q Yu, D Li, JR Pearl, JC Miller, ...
Nature medicine 25 (7), 1131-1142, 2019
Multiple Dual Specificity Protein Tyrosine Phosphatases Are Expressed and Regulated Differentially in Liver Cell Lines (∗)
SP Kwak, JE Dixon
Journal of Biological Chemistry 270 (3), 1156-1160, 1995
The HTT CAG-expansion mutation determines age at death but not disease duration in Huntington disease
JW Keum, A Shin, T Gillis, JS Mysore, KA Elneel, D Lucente, T Hadzi, ...
The American Journal of Human Genetics 98 (2), 287-298, 2016
hVH‐5: A protein tyrosine phosphatase abundant in brain that inactivates mitogen‐activated protein kinase
KJ Martell, AF Seasholtz, SP Kwak, KK Clemens, JE Dixon
Journal of neurochemistry 65 (4), 1823-1833, 1995
A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and DNA repair gene variants, with Huntington disease clinical outcomes
M Ciosi, A Maxwell, SA Cumming, DJH Moss, AM Alshammari, MD Flower, ...
EBioMedicine 48, 568-580, 2019
Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington’s disease
XH Lu, VB Mattis, N Wang, I Al-Ramahi, N van den Berg, SA Fratantoni, ...
Science translational medicine 6 (268), 268ra178-268ra178, 2014
Characterization of the WAVE1 knock-out mouse: implications for CNS development
JP Dahl, J Wang-Dunlop, C Gonzales, MEP Goad, RJ Mark, SP Kwak
Journal of Neuroscience 23 (8), 3343-3352, 2003
Myostatin inhibition slows muscle atrophy in rodent models of amyotrophic lateral sclerosis
ELF Holzbaur, DS Howland, N Weber, K Wallace, Y She, S Kwak, ...
Neurobiology of disease 23 (3), 697-707, 2006
5'-Heterogeneity of the mineralocorticoid receptor messenger ribonucleic acid: differential expression and regulation of splice variants within the rat hippocampus
SP Kwak, PD Patel, RC Thompson, H Akil, SJ Watson
Endocrinology 133 (5), 2344-2350, 1993
WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelination
HJ Kim, AB DiBernardo, JA Sloane, MN Rasband, D Solomon, B Kosaras, ...
Journal of Neuroscience 26 (21), 5849-5859, 2006
A novel receptor-type protein tyrosine phosphatase is expressed during neurogenesis in the olfactory neuroepithelium
KM Walton, KJ Martell, SP Kwak, JE Dixon, BL Largent
Neuron 11 (2), 387-400, 1993
A modifier of Huntington's disease onset at the MLH1 locus
JM Lee, MJ Chao, D Harold, K Abu Elneel, T Gillis, P Holmans, L Jones, ...
Human molecular genetics 26 (19), 3859-3867, 2017
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20