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Frank Szulzewsky
Frank Szulzewsky
Dirección de correo verificada de fredhutch.org
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Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1
F Szulzewsky, A Pelz, X Feng, M Synowitz, D Markovic, T Langmann, ...
PloS one 10 (2), e0116644, 2015
4012015
Mutant IDH1 regulates the tumor-associated immune system in gliomas
NM Amankulor, Y Kim, S Arora, J Kargl, F Szulzewsky, M Hanke, ...
Genes & Development 31 (8), 774-786, 2017
3452017
Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis
X Feng, F Szulzewsky, A Yerevanian, Z Chen, D Heinzmann, ...
Oncotarget 6 (17), 15077, 2015
1952015
Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion
K Vinnakota, F Hu, MC Ku, PB Georgieva, F Szulzewsky, A Pohlmann, ...
Neuro-oncology 15 (11), 1457-1468, 2013
1412013
Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression
A De Boeck, BY Ahn, C D’Mello, X Lun, SV Menon, MM Alshehri, ...
Nature communications 11 (1), 1-24, 2020
1262020
Human glioblastoma‐associated microglia/monocytes express a distinct RNA profile compared to human control and murine samples
F Szulzewsky, S Arora, L de Witte, T Ulas, D Markovic, JL Schultze, ...
Glia 64 (8), 1416-1436, 2016
1072016
Vascular signal transducer and activator of transcription-3 promotes angiogenesis and neuroplasticity long-term after stroke
CJ Hoffmann, U Harms, A Rex, F Szulzewsky, SA Wolf, U Grittner, ...
Circulation 131 (20), 1772-1782, 2015
972015
Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors
I Kaffes, F Szulzewsky, Z Chen, CJ Herting, B Gabanic, ...
OncoImmunology 8 (11), e1655360, 2019
862019
YAP1 and its fusion proteins in cancer initiation, progression and therapeutic resistance
F Szulzewsky, EC Holland, V Vasioukhin
Developmental Biology, 2021
782021
Altered microglial phagocytosis in GPR34‐deficient mice
J Preissler, A Grosche, V Lede, D Le Duc, K Krügel, V Matyash, ...
Glia 63 (2), 206-215, 2015
772015
The subpopulation of microglia sensitive to neurotransmitters/neurohormones is modulated by stimulation with LPS, interferon‐γ, and IL‐4
M Pannell, F Szulzewsky, V Matyash, SA Wolf, H Kettenmann
Glia 62 (5), 667-679, 2014
712014
Genetic driver mutations define the expression signature and microenvironmental composition of high‐grade gliomas
CJ Herting, Z Chen, KL Pitter, F Szulzewsky, I Kaffes, M Kaluzova, ...
Glia 65 (12), 1914-1926, 2017
622017
The subpopulation of microglia expressing functional muscarinic acetylcholine receptors expands in stroke and Alzheimer’s disease
M Pannell, MA Meier, F Szulzewsky, V Matyash, M Endres, G Kronenberg, ...
Brain Structure and Function 221, 1157-1172, 2016
622016
A De Novo Mouse Model of C11orf95-RELA Fusion-Driven Ependymoma Identifies Driver Functions in Addition to NF-κB
T Ozawa, S Arora, F Szulzewsky, G Juric-Sekhar, Y Miyajima, H Bolouri, ...
Cell Reports 23 (13), 3787-3797, 2018
612018
Tumour-associated macrophage-derived interleukin-1 mediates glioblastoma-associated cerebral oedema
CJ Herting, Z Chen, V Maximov, A Duffy, F Szulzewsky, ...
Brain 142 (12), 3834-3851, 2019
592019
Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis
F Szulzewsky, S Arora, P Hoellerbauer, C King, E Nathan, M Chan, ...
Genes & Development 34 (15-16), 1051-1064, 2020
552020
Platelet-derived growth factor beta is a potent inflammatory driver in paediatric high-grade glioma
JL Ross, Z Chen, CJ Herting, Y Grabovska, F Szulzewsky, M Puigdelloses, ...
Brain 144 (1), 53-69, 2021
482021
Increased HOXA5 expression provides a selective advantage for gain of whole chromosome 7 in IDH wild-type glioblastoma
PJ Cimino, Y Kim, HJ Wu, J Alexander, HG Wirsching, F Szulzewsky, ...
Genes & development 32 (7-8), 512-523, 2018
482018
NTPDase1 activity attenuates microglial phagocytosis
L Bulavina, F Szulzewsky, A Rocha, G Krabbe, SC Robson, V Matyash, ...
Purinergic signalling 9 (2), 199-205, 2013
462013
Anti–PD-L1 antibody direct activation of macrophages contributes to a radiation-induced abscopal response in glioblastoma
CI Ene, SA Kreuser, M Jung, H Zhang, S Arora, K White Moyes, ...
Neuro-oncology 22 (5), 639-651, 2020
432020
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