| Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease A George, S Pushkaran, DG Konstantinidis, S Koochaki, P Malik, ... Blood, The Journal of the American Society of Hematology 121 (11), 2099-2107, 2013 | 204 | 2013 |
| Signaling and cytoskeletal requirements in erythroblast enucleation DG Konstantinidis, S Pushkaran, JF Johnson, JA Cancelas, S Manganaris, ... Blood, The Journal of the American Society of Hematology 119 (25), 6118-6127, 2012 | 145 | 2012 |
| The ambiguous role of the Na+–H+ exchanger isoform 1 (NHE1) in leptin-induced oxidative stress in human monocytes D Konstantinidis, K Paletas, G Koliakos, M Kaloyianni Cell Stress and Chaperones 14 (6), 591-601, 2009 | 40 | 2009 |
| Gene targeting RhoA reveals its essential role in coordinating mitochondrial function and thymocyte development S Zhang, DG Konstantinidis, JQ Yang, B Mizukawa, K Kalim, RA Lang, ... The Journal of Immunology 193 (12), 5973-5982, 2014 | 38 | 2014 |
| Cytokinesis failure in RhoA-deficient mouse erythroblasts involves actomyosin and midbody dysregulation and triggers p53 activation DG Konstantinidis, KM Giger, M Risinger, S Pushkaran, P Zhou, ... Blood, The Journal of the American Society of Hematology 126 (12), 1473-1482, 2015 | 37 | 2015 |
| Signaling components involved in leptin-induced amplification of the atherosclerosis-related properties of human monocytes D Konstantinidis, K Paletas, G Koliakos, M Kaloyianni Journal of vascular research 46 (3), 199-208, 2009 | 32 | 2009 |
| Inhibition of the Na+-H+ Exchanger Isoform-1 and the Extracellular Signal-Regulated Kinase Induces Apoptosis: a Time Course of Events D Konstantinidis, G Koliakos, K Vafia, P Liakos, C Bantekas, V Trachana, ... Cellular physiology and biochemistry 18 (4-5), 211-222, 2006 | 25 | 2006 |
| Etavopivat, a pyruvate kinase activator in red blood cells, for the treatment of sickle cell disease P Schroeder, K Fulzele, S Forsyth, MD Ribadeneira, S Guichard, E Wilker, ... Journal of Pharmacology and Experimental Therapeutics 380 (3), 210-219, 2022 | 22 | 2022 |
| Erythroblastic islands foster granulopoiesis in parallel to terminal erythropoiesis L Romano, KG Seu, J Papoin, DE Muench, D Konstantinidis, A Olsson, ... Blood, The Journal of the American Society of Hematology 140 (14), 1621-1634, 2022 | 16 | 2022 |
| Safety, Pharmacokinetics, and Pharmacodynamics of Etavopivat (FT‐4202), an Allosteric Activator of Pyruvate Kinase‐R, in Healthy Adults: A Randomized, Placebo‐Controlled … S Forsyth, P Schroeder, J Geib, L Vrishabhendra, DG Konstantinidis, ... Clinical Pharmacology in Drug Development 11 (5), 654-665, 2022 | 16 | 2022 |
| Increased oxidative stress in sickle cell disease activates the renin-angiotensin-TGF-β pathway to mediate sickle nephropathy S Roy, DG Konstantinidis, T Rizvi, KH Chang, N Sundaram, M Wourms, ... Blood 122 (21), 2211, 2013 | 15 | 2013 |
| Rac GTPases in erythroid biology DG Konstantinidis, A George, TA Kalfa Transfusion clinique et biologique 17 (3), 126-130, 2010 | 14 | 2010 |
| Automated oxygen gradient ektacytometry: a novel biomarker in sickle cell anemia A Sadaf, KG Seu, E Thaman, R Fessler, DG Konstantinidis, HA Bonar, ... Frontiers in Physiology 12, 636609, 2021 | 13 | 2021 |
| Phase 1 single (SAD) and multiple ascending dose (MAD) studies of the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of FT-4202, an allosteric activator … TA Kalfa, FA Kuypers, MJ Telen, P Malik, DG Konstantinidis, JH Estepp, ... Blood 134, 616, 2019 | 11 | 2019 |
| Identification of a murine erythroblast subpopulation enriched in enucleating events by multi-spectral imaging flow cytometry DG Konstantinidis, S Pushkaran, K Giger, S Manganaris, Y Zheng, ... JoVE (Journal of Visualized Experiments), e50990, 2014 | 8 | 2014 |
| Ex-vivo FT-4202 treatment improves hemoglobin oxygen affinity and membrane health in red blood cells of patients with hemoglobin SS and hemoglobin SC disease irrespective of … DG Konstantinidis, R Fessler, KG Seu, B Patel, JB Korpik, K Fulzele, ... Blood 136, 23-24, 2020 | 7 | 2020 |
| Effect of epinephrine and insulin resistance on human monocytes obtained from lean and obese healthy participants: a pilot study M Sarigianni, E Bekiari, A Tsapas, D Konstantinidis, M Kaloyianni, ... Angiology 62 (1), 38-45, 2011 | 7 | 2011 |
| Angiotensin Signaling Is Essential for Stress Erythropoiesis but Results in Retention of Dysfunctional Mitochondria in Erythrocytes That Generate Excessive Reactive Oxygen Species P Rai, S Roy, DG Konstantinidis, SR Ponny, MEM Mpollo, A Shrestha, ... Blood 136, 31-32, 2020 | 1 | 2020 |
| The Erythro-Myeloblastic Island (EMBI): A Hematopoietic Niche Balancing Erythropoiesis and Myelopoiesis K Giger Seu, L Romano, J Papoin, ED Muench, D Konstantinidis, ... Blood, The Journal of the American Society of Hematology 132 (Supplement 1 …, 2018 | 1 | 2018 |
| Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease (vol 121, pg 2099, 2013) A George, S Pushkaran, DG Konstantinidis Blood 123 (12), 1972-1972, 2014 | 1 | 2014 |
