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Felipe Paredes
Felipe Paredes
Division of Cardiology, School of Medicine, Emory University
Dirección de correo verificada de ciq.uchile.cl
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Endoplasmic reticulum and the unfolded protein response: dynamics and metabolic integration
R Bravo, V Parra, D Gatica, AE Rodriguez, N Torrealba, F Paredes, ...
International review of cell and molecular biology 301, 215-290, 2013
6612013
Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics
R Bravo, T Gutierrez, F Paredes, D Gatica, AE Rodriguez, Z Pedrozo, ...
The international journal of biochemistry & cell biology 44 (1), 16-20, 2012
2042012
Metabolic adaptation in hypoxia and cancer
F Paredes, HC Williams, A San Martin
Cancer letters 502, 133-142, 2021
1122021
Dexamethasone-induced autophagy mediates muscle atrophy through mitochondrial clearance
R Troncoso, F Paredes, V Parra, D Gatica, C Vásquez-Trincado, ...
Cell Cycle 13 (14), 2281-2295, 2014
1092014
Organelle communication: signaling crossroads between homeostasis and disease
R Bravo-Sagua, N Torrealba, F Paredes, PE Morales, C Pennanen, ...
The international journal of biochemistry & cell biology 50, 55-59, 2014
602014
Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer
F Paredes, K Sheldon, B Lassègue, HC Williams, EA Faidley, ...
Proceedings of the National Academy of Sciences 115 (8), 1789-1794, 2018
592018
GLP-1 promotes mitochondrial metabolism in vascular smooth muscle cells by enhancing endoplasmic reticulum–mitochondria coupling
PE Morales, G Torres, C Sotomayor-Flores, D Peña-Oyarzún, ...
Biochemical and Biophysical Research Communications 446 (1), 410-416, 2014
482014
HERPUD1 protects against oxidative stress-induced apoptosis through downregulation of the inositol 1, 4, 5-trisphosphate receptor
F Paredes, V Parra, N Torrealba, M Navarro-Marquez, D Gatica, ...
Free Radical Biology and Medicine 90, 206-218, 2016
432016
Herp depletion protects from protein aggregation by up-regulating autophagy
C Quiroga, D Gatica, F Paredes, R Bravo, R Troncoso, Z Pedrozo, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (12), 3295-3305, 2013
342013
Mitochondrial protein Poldip2 (polymerase delta interacting protein 2) controls vascular smooth muscle differentiated phenotype by O-linked GlcNAc (N-acetylglucosamine …
F Paredes, HC Williams, RA Quintana, A San Martin
Circulation research 126 (1), 41-56, 2020
262020
Poldip2 takes a central role in metabolic reprograming
F Paredes, I Suster, A San Martin
Oncoscience 5 (5-6), 130, 2018
52018
Poldip2 is an oxygen-sensitive mitochondrial protein that controls oxidative/glycolytic metabolism balance and proteasome activity
F Paredes, H Williams, A San Martin
Free Radical Biology and Medicine 112, 173-174, 2017
42017
HERPUD1 governs tumor cell mitochondrial function via inositol 1, 4, 5-trisphosphate receptor-mediated calcium signaling
F Paredes, M Navarro-Marquez, C Quiroga, D Jiménez-Gallegos, ...
Free Radical Biology and Medicine 211, 24-34, 2024
12024
Mitochondrial protein Poldip2 controls VSMC differentiated phenotype by O-linked GlcNAc transferase-dependent inhibition of a ubiquitin proteasome system
F Paredes, HC Williams, RA Quintana, A San Martin
Circulation research 126 (1), 41, 2020
12020
The Mitochondrial Protease is a Druggable Target That ClpXP Controls the VSMC Phenotype to Inhibit Aortic Aneurysms
F Paredes, HC Williams, X Liu, C Holden, BJ Bogan, Y Wang, KM Crotty, ...
CIRCULATION RESEARCH 133 (12), E58-E58, 2023
2023
The Role Of Peroxisomes And Bile Acid-initiated Signaling In Vascular Smooth Muscle Cell Phenotype
CM Holden, B Bogan, F Paredes, A San Martin
Arteriosclerosis, Thrombosis, and Vascular Biology 43 (Suppl_1), A407-A407, 2023
2023
Metabolic regulation of the proteasome under hypoxia by Poldip2 controls fibrotic signaling in vascular smooth muscle cells
F Paredes, HC Williams, I Suster, M Tejos, R Fuentealba, B Bogan, ...
Free Radical Biology and Medicine 195, 283-297, 2023
2023
The Role of Bile Acid Signaling in Differentiation of Vascular Smooth Muscle Cells
C Holden, B Bogan, A San Martin, F Paredes
Free Radical Biology and Medicine 192, 62-63, 2022
2022
PGC-1alpha deficiency attenuates vascular smooth muscle atherogenic phenotypic plasticity
C Holden, F Paredes, HC Williams, R Taylor, A San Martin
Free Radical Biology and Medicine 180, 46-47, 2022
2022
The mitochondrial protease ClpXP regulates the phenotype of VSMC by a SIRT1-dependent mechanism
F Paredes, A San Martin, HC Williams
Free Radical Biology and Medicine 180, 97-97, 2022
2022
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