Exposure to titanium dioxide and other metallic oxide nanoparticles induces cytotoxicity on human neural cells and fibroblasts JCK Lai, MB Lai, S Jandhyam, VV Dukhande, A Bhushan, CK Daniels, ... International journal of nanomedicine 3 (4), 533-545, 2008 | 312 | 2008 |
Nuclear glycogenolysis modulates histone acetylation in human non-small cell lung cancers RC Sun, VV Dukhande, Z Zhou, LEA Young, S Emanuelle, CF Brainson, ... Cell metabolism 30 (5), 903-916. e7, 2019 | 100 | 2019 |
Manganese-induced neurotoxicity is differentially enhanced by glutathione depletion in astrocytoma and neuroblastoma cells VV Dukhande, GH Malthankar-Phatak, JJ Hugus, CK Daniels, JCK Lai Neurochemical Research 31, 1349-1357, 2006 | 95 | 2006 |
Structural mechanism of laforin function in glycogen dephosphorylation and lafora disease M Raththagala, MK Brewer, MW Parker, AR Sherwood, BK Wong, S Hsu, ... Molecular cell 57 (2), 261-272, 2015 | 66 | 2015 |
Treatment of human astrocytoma U87 cells with silicon dioxide nanoparticles lowers their survival and alters their expression of mitochondrial and cell signaling proteins JCK Lai, G Ananthakrishnan, S Jandhyam, VV Dukhande, A Bhushan, ... International Journal of Nanomedicine, 715-723, 2010 | 59 | 2010 |
Nanoformulation of PROteolysis TArgeting Chimera targeting ‘undruggable’ c-Myc for the treatment of pancreatic cancer A Saraswat, M Patki, Y Fu, S Barot, VV Dukhande, K Patel Nanomedicine 15 (18), 1761-1777, 2020 | 57 | 2020 |
HUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold ER Jang, P Shi, J Bryant, J Chen, V Dukhande, MS Gentry, HI Jang, ... Molecular and cellular biology 34 (19), 3579-3593, 2014 | 48 | 2014 |
Laforin, a dual-specificity phosphatase involved in Lafora disease, is phosphorylated at Ser25 by AMP-activated protein kinase C Romá-Mateo, MC Solaz-Fuster, JV Gimeno-Alcañiz, VV Dukhande, ... Biochemical Journal 439 (2), 265-275, 2011 | 35 | 2011 |
Laforin, a dual specificity phosphatase involved in Lafora disease, is present mainly as monomeric form with full phosphatase activity VV Dukhande, DM Rogers, C Romá-Mateo, J Donderis, A Marina, ... PloS one 6 (8), e24040, 2011 | 32 | 2011 |
Reduced glutathione regenerating enzymes undergo developmental decline and sexual dimorphism in the rat cerebral cortex VV Dukhande, AO Isaac, T Chatterji, JCK Lai Brain research 1286, 19-24, 2009 | 32 | 2009 |
Inhibition of glycogen catabolism induces intrinsic apoptosis and augments multikinase inhibitors in hepatocellular carcinoma cells S Barot, EM Abo-Ali, DL Zhou, C Palaguachi, VV Dukhande Experimental cell research 381 (2), 288-300, 2019 | 30 | 2019 |
Development of dual ARV-825 and nintedanib-loaded PEGylated nano-liposomes for synergistic efficacy in vemurafnib-resistant melanoma Y Fu, A Saraswat, Z Wei, MY Agrawal, VV Dukhande, SE Reznik, K Patel Pharmaceutics 13 (7), 1005, 2021 | 28 | 2021 |
Galactose-decorated liver tumor-specific nanoliposomes incorporating selective BRD4-targeted PROTAC for hepatocellular carcinoma therapy A Saraswat, HP Vemana, VV Dukhande, K Patel Heliyon 8 (1), 2022 | 24 | 2022 |
EphA2-Receptor Targeted PEGylated Nanoliposomes for the Treatment of BRAFV600E Mutated Parent- and Vemurafenib-Resistant Melanoma Y Fu, D Rathod, EM Abo-Ali, VV Dukhande, K Patel Pharmaceutics 11 (10), 504, 2019 | 23 | 2019 |
Structural modification of the aryl sulfonate ester of cjoc42 for enhanced gankyrin binding and anti-cancer activity D Kanabar, P Farrales, M Gnanamony, J Almasri, EM Abo-Ali, Y Otmankel, ... Bioorganic & Medicinal Chemistry Letters 30 (4), 126889, 2020 | 22 | 2020 |
Neuroprotection against neuroblastoma cell death induced by depletion of mitochondrial glutathione VV Dukhande, I Kawikova, ALM Bothwell, JCK Lai Apoptosis 18, 702-712, 2013 | 18 | 2013 |
A novel gene therapy for neurodegenerative Lafora disease via EPM2A-loaded DLinDMA lipoplexes HP Vemana, A Saraswat, S Bhutkar, K Patel, VV Dukhande Nanomedicine 16 (13), 1081-1095, 2021 | 16 | 2021 |
Metabolic and antioxidant system alterations in an astrocytoma cell line challenged with mitochondrial DNA deletion AO Isaac, VV Dukhande, JCK Lai Neurochemical Research 32, 1906-1918, 2007 | 16 | 2007 |
In vitro assessment of a synergistic combination of gemcitabine and zebularine in pancreatic cancer cells M Patki, A Saraswat, S Bhutkar, V Dukhande, K Patel Experimental cell research 405 (2), 112660, 2021 | 14 | 2021 |
Chronic hypoxia-induced alterations of key enzymes of glucose oxidative metabolism in developing mouse liver are mTOR dependent VV Dukhande, GC Sharma, JCK Lai, R Farahani Molecular and cellular biochemistry 357, 189-197, 2011 | 14 | 2011 |