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Carlos A. H. Fernandes
Carlos A. H. Fernandes
Secretariat of Education of the State of São Paulo
Dirección de correo verificada de unesp.br - Página principal
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A structure-based proposal for a comprehensive myotoxic mechanism of phospholipase A2-like proteins from viperid snake venoms
CAH Fernandes, RJ Borges, B Lomonte, MRM Fontes
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1844 (12), 2265-2276, 2014
842014
Secreted Phospholipases A2 from Animal Venoms in Pain and Analgesia
VO Zambelli, G Picolo, CAH Fernandes, MRM Fontes, Y Cury
Toxins 9 (12), 406, 2017
532017
Structural, functional, and bioinformatics studies reveal a new snake venom homologue phospholipase A2 class
JI dos Santos, M Cintra‐Francischinelli, RJ Borges, CAH Fernandes, ...
Proteins: Structure, Function, and Bioinformatics 79 (1), 61-78, 2011
512011
Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca2+-binding loop region for the catalytically inactive Lys49-PLA2s
CAH Fernandes, DP Marchi-Salvador, GM Salvador, MCO Silva, ...
Journal of Structural Biology 171 (1), 31-43, 2010
502010
Structural Basis for the Inhibition of a Phospholipase A2-Like Toxin by Caffeic and Aristolochic Acids
CAH Fernandes, FF Cardoso, WGL Cavalcante, AM Soares, M Dal-Pai, ...
PLoS One 10 (7), e0133370, 2015
392015
Structural bases for a complete myotoxic mechanism: crystal structures of two non-catalytic phospholipases A2-like from Bothrops brazili venom
CAH Fernandes, EJ Comparetti, RJ Borges, S Huancahuire-Vega, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (12), 2772-2781, 2013
382013
Crystal structure of a phospholipase A2 homolog complexed with p-bromophenacyl bromide reveals important structural changes associated with the inhibition of myotoxic activity
DP Marchi-Salvador, CAH Fernandes, LB Silveira, AM Soares, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1794 (11), 1583-1590, 2009
382009
The intriguing phospholipases A2 homologues: relevant structural features on myotoxicity and catalytic inactivity
JI dos Santos, CAH Fernandes, AJ Magro, MRM Fontes
Protein and Peptide Letters 16 (8), 887-893, 2009
342009
Replication Protein A Presents Canonical Functions and Is Also Involved in the Differentiation Capacity of Trypanosoma cruzi
RS Pavani, MS da Silva, CAH Fernandes, FS Morini, CB Araujo, ...
PLoS Neglected Tropical Diseases 10 (12), e0005181, 2016
272016
Functional and structural studies of a Phospholipase A2-like protein complexed to zinc ions: Insights on its myotoxicity and inhibition mechanism
RJ Borges, FF Cardoso, CAH Fernandes, TR Dreyer, DS de Moraes, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (1), 3199-3209, 2017
262017
Molecular cloning and biochemical characterization of a myotoxin inhibitor from Bothrops alternatus snake plasma
NA Santos-Filho, CAH Fernandes, DL Menaldo, AJ Magro, ...
Biochimie 93 (3), 583-592, 2011
232011
Biophysical studies suggest a new structural arrangement of crotoxin and provide insights into its toxic mechanism
CAH Fernandes, WM Pazin, TR Dreyer, RN Bicev, WLG Cavalcante, ...
Scientific reports 7 (1), 1-15, 2017
222017
Structural and Phylogenetic Studies with MjTX-I Reveal a Multi-Oligomeric Toxin – a Novel Feature in Lys49-PLA2s Protein Class
GHM Salvador, CAH Fernandes, AJ Magro, DP Marchi-Salvador, ...
PLoS One 8 (4), e60610, 2013
212013
In vivo uptake of a haem analogue Zn protoporphyrin IX by the human malaria parasite P. falciparum‐infected red blood cells
R Sartorello, A Budu, P Bagnaresi, CAH Fernandes, PM Sato, VB Bueno, ...
Cell biology international 34 (8), 859-865, 2010
192010
Influence of quaternary conformation on the biological activities of the Asp49-phospholipases A2s from snake venoms
AJ Magro, CAH Fernandes, JI dos Santos, MRM Fontes
Protein and Peptide Letters 16 (8), 852-859, 2009
192009
RPA-1 from Leishmania amazonensis (LaRPA-1) structurally differs from other eukaryote RPA-1 and interacts with telomeric DNA via its N-terminal OB-fold domain
RS Pavani, C Fernandes, AM Perez, EJR Vasconcelos, JL Siqueira-Neto, ...
FEBS letters 588 (24), 4740-4748, 2014
172014
Biochemical, functional, structural and phylogenetic studies on Intercro, a new isoform phospholipase A2 from Crotalus durissus terrificus snake venom
LF Vieira, AJ Magro, CAH Fernandes, BM de Souza, WLG Cavalcante, ...
Biochimie 95 (12), 2365-2375, 2013
172013
Insights on the structure of native CNF, an endogenous phospholipase A2 inhibitor from Crotalus durissus terrificus, the South American rattlesnake
CL Fortes-Dias, PL Ortolani, CAH Fernandes, KR Lobo, LA de Melo, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1844 (9), 1569-1579, 2014
162014
Structural and evolutionary insights into endogenous alpha-phospholipase A2 inhibitors of Latin American pit vipers
MI Estevão-Costa, CAH Fernandes, M de Alvarenga Mudadu, GR Franco, ...
Toxicon 112, 35-44, 2016
132016
Biophysical characterization of the recombinant importin-α from Neurospora crassa
A AS Takeda, F Z Freitas, A J Magro, N E Bernardes, C AH Fernandes, ...
Protein and peptide letters 20 (1), 8-16, 2013
122013
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Artículos 1–20