Ville Härmä
Ville Härmä
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A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses
V Härmä, J Virtanen, R Mäkelä, A Happonen, JP Mpindi, M Knuuttila, ...
PloS one 5 (5), e10431, 2010
Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion
M Björkman, P Östling, V Härmä, J Virtanen, JP Mpindi, J Rantala, T Mirtti, ...
Oncogene 31 (29), 3444-3456, 2012
Quantification of dynamic morphological drug responses in 3D organotypic cell cultures by automated image analysis
V Härmä, HP Schukov, A Happonen, I Ahonen, J Virtanen, H Siitari, ...
PloS one 9 (5), e96426, 2014
Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models
V Härmä, M Knuuttila, J Virtanen, T Mirtti, P Kohonen, P Kovanen, ...
Oncogene 31 (16), 2075-2089, 2012
Direct transfection of clonal organoids in Matrigel microbeads: a promising approach toward organoid-based genetic screens
B Laperrousaz, S Porte, S Gerbaud, V Härmä, F Kermarrec, V Hourtane, ...
Nucleic acids research 46 (12), e70-e70, 2018
Automated tracking of tumor-stroma morphology in microtissues identifies functional targets within the tumor microenvironment for therapeutic intervention
M Åkerfelt, N Bayramoglu, S Robinson, M Toriseva, HP Schukov, ...
Oncotarget 6 (30), 30035, 2015
Optimization of invasion-specific effects of betulin derivatives on prostate cancer cells through lead development
V Härmä, R Haavikko, J Virtanen, I Ahonen, HP Schukov, S Alakurtti, ...
PLoS One 10 (5), e0126111, 2015
Image-based ex vivo drug screen to assess targeted therapies in recurrent thymoma
A Arjonen, R Mäkelä, V Härmä, N Rintanen, T Kuopio, J Kononen, ...
Lung Cancer 145, 27-32, 2020
Ex vivo modelling of drug efficacy in a rare metastatic urachal carcinoma
R Mäkelä, A Arjonen, V Härmä, N Rintanen, L Paasonen, T Paprotka, ...
BMC cancer 20, 1-10, 2020
Ex vivo assessment of targeted therapies in a rare metastatic epithelial–myoepithelial carcinoma
R Mäkelä, A Arjonen, AS Rahmanto, V Härmä, J Lehtiö, T Kuopio, ...
Neoplasia 22 (9), 390-398, 2020
Morphological clustering of cell cultures based on size, shape, and texture features
I Ahonen, V Härmä, HP Schukov, M Nees, J Nevalainen
Statistics in Biopharmaceutical Research 8 (2), 217-228, 2016
Defined extracellular matrix compositions support stiffness-insensitive cell spreading and adhesion signaling
JRW Conway, A Isomursu, G Follain, V Härmä, E Jou-Ollé, N Pasquier, ...
Proceedings of the National Academy of Sciences 120 (43), e2304288120, 2023
Ex vivo analysis of DNA repair targeting in extreme rare cutaneous apocrine sweat gland carcinoma
R Mäkelä, V Härmä, NB Fajardo, G Wells, Z Lygerou, O Sangfelt, ...
Oncotarget 12 (11), 1100, 2021
Ex Vivo Drug Screening Informed Targeted Therapy for Metastatic Parotid Squamous Cell Carcinoma
N Nykänen, R Mäkelä, A Arjonen, V Härmä, L Lewandowski, E Snowden, ...
Frontiers in Oncology 11, 735820, 2021
VTT-006, an anti-mitotic compound, binds to the Ndc80 complex and suppresses cancer cell growth in vitro
LJ Laine, JHE Mäki-Jouppila, E Kutvonen, P Tiikkainen, TKM Nyholm, ...
Oncoscience 8, 134, 2021
A Farewell to Flat Biology
V Härmä
Turku: Turun Yliopisto, 2012
Advanced Models for Target Validation & Drug Discovery in Prostate Cancer
M Åkerfelt, V Härmä, M Nees
Prostate Cancer-From Bench to Bedside, 2011
Intranasal neomycin evokes broad-spectrum antiviral immunity in the upper respiratory tract
T Mao, J Kim, MA Peña-Hernández, G Valle, M Moriyama, S Luyten, ...
Proceedings of the National Academy of Sciences 121 (18), e2319566121, 2024
Suggested searches
P Sacchi, SE Wright, P Neoptolemou, GI Lampronti, AK Rajagopalan, ...
Perspective, 2024
Science Repository
A Arjonen, R Mäkelä, R Virtakoivu, V Härmä, T Kuopio, H Hakkarainen, ...
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Artículos 1–20