Membrane transporters in drug development Nature reviews Drug discovery 9 (3), 215-236, 2010 | 3483 | 2010 |
Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1 A Siddiqui, R Kerb, ME Weale, U Brinkmann, A Smith, DB Goldstein, ... New England Journal of Medicine 348 (15), 1442-1448, 2003 | 854 | 2003 |
High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1) M Niemi, E Schaeffeler, T Lang, MF Fromm, M Neuvonen, C Kyrklund, ... Pharmacogenetics and Genomics 14 (7), 429-440, 2004 | 510 | 2004 |
Combined Analysis of Inherited Polymorphisms in Arylamine N-Acetyltransferase 2, Glutathione S-Transferases M1 and T1, Microsomal Epoxide Hydrolase, and … J Brockmöller, I Cascorbi, R Kerb, I Roots Cancer Research 56 (17), 3915-3925, 1996 | 474 | 1996 |
Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group M Schwab, UM Zanger, C Marx, E Schaeffeler, K Klein, J Dippon, R Kerb, ... Journal of clinical oncology 26 (13), 2131-2138, 2008 | 467 | 2008 |
Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver AT Nies, H Koepsell, S Winter, O Burk, K Klein, R Kerb, UM Zanger, ... Hepatology 50 (4), 1227-1240, 2009 | 439 | 2009 |
Modulation of steady‐state kinetics of digoxin by haplotypes of the P‐glycoprotein MDR1 gene A Johne, K Köpke, T Gerloff, I Mai, S Rietbrock, C Meisel, S Hoffmeyer, ... Clinical Pharmacology & Therapeutics 72 (5), 584-594, 2002 | 417 | 2002 |
Intraperitoneal chemotherapy of peritoneal carcinomatosis using pressurized aerosol as an alternative to liquid solution: first evidence for efficacy W Solass, R Kerb, T Mürdter, U Giger-Pabst, D Strumberg, C Tempfer, ... Annals of surgical oncology 21, 553-559, 2014 | 396 | 2014 |
Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury C Lang, Y Meier, B Stieger, U Beuers, T Lang, R Kerb, GA Kullak-Ublick, ... Pharmacogenetics and genomics 17 (1), 47-60, 2007 | 371 | 2007 |
Association of the P-glycoprotein transporter MDR1C3435T polymorphism with the susceptibility to renal epithelial tumors M Siegsmund, U Brinkmann, E Scha, G Weirich, M Schwab, ... Journal of the American Society of Nephrology 13 (7), 1847-1854, 2002 | 346 | 2002 |
Sequence analysis of bile salt export pump (ABCB11) and multidrug resistance p-glycoprotein 3 (ABCB4, MDR3) in patients with intrahepatic cholestasis of pregnancy C Pauli-Magnus, T Lang, Y Meier, T Zodan-Marin, D Jung, C Breymann, ... Pharmacogenetics and Genomics 14 (2), 91-102, 2004 | 328 | 2004 |
Implications of genetic polymorphisms in drug transporters for pharmacotherapy R Kerb Cancer letters 234 (1), 4-33, 2006 | 302 | 2006 |
Hypericin and pseudohypericin: pharmacokinetics and effects on photosensitivity in humans J Brockmöller, T Reum, S Bauer, R Kerb, WD Hübner, I Roots Pharmacopsychiatry 30 (S 2), 94-101, 1997 | 289 | 1997 |
ABC drug transporters: hereditary polymorphisms and pharmacological impact in MDR1, MRP1 and MRP2 R Kerb, S Hoffmeyer, U Brinkmann Pharmacogenomics 2 (1), 51-64, 2001 | 275 | 2001 |
Genotype and Phenotype of Glutathione S-Transferase Class µ Isoenzymes µ and ψ in Lung Cancer Patients and Controls J Brockmöller, R Kerb, N Drakoulis, M Nitz, I Roots Cancer research 53 (5), 1004-1011, 1993 | 262 | 1993 |
Identification of genetic variations of the human organic cation transporter hOCT1 and their functional consequences R Kerb, U Brinkmann, N Chatskaia, D Gorbunov, V Gorboulev, ... Pharmacogenetics and genomics 12 (8), 591-595, 2002 | 261 | 2002 |
Digoxin pharmacokinetics and MDR1 genetic polymorphisms C Verstuyft, M Schwab, E Schaeffeler, R Kerb, U Brinkmann, P Jaillon, ... European journal of clinical pharmacology 58, 809-812, 2003 | 241 | 2003 |
Characterization of the glutathione S-transferase GSTT1 deletion: discrimination of all genotypes by polymerase chain reaction indicates a trimodular genotype–phenotype correlation R Sprenger, R Schlagenhaufer, R Kerb, C Bruhn, J Brockmöller, I Roots, ... Pharmacogenetics and Genomics 10 (6), 557-565, 2000 | 226 | 2000 |
Glutathione S-Transferase M1 and Its Variants A and B as Host Factors of Bladder Cancer Susceptibility: A Case-Control Study J Brockmöller, R Kerb, N Drakoulis, B Staffeldt, I Roots Cancer Research 54 (15), 4103-4111, 1994 | 215 | 1994 |
Effect of grapefruit juice on digoxin pharmacokinetics in humans L Becquemont, C Verstuyft, R Kerb, U Brinkmann, M Lebot, P Jaillon, ... Clinical Pharmacology & Therapeutics 70 (4), 311-316, 2001 | 213 | 2001 |