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Dr. Alexander Schulte
Dr. Alexander Schulte
Scientist
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The transmembrane CXC-chemokine ligand 16 is induced by IFN-γ and TNF-α and shed by the activity of the disintegrin-like metalloproteinase ADAM10
S Abel, C Hundhausen, R Mentlein, A Schulte, TA Berkhout, N Broadway, ...
The Journal of Immunology 172 (10), 6362-6372, 2004
5152004
Hematogenous dissemination of glioblastoma multiforme
C Müller, J Holtschmidt, M Auer, E Heitzer, K Lamszus, A Schulte, ...
Science translational medicine 6 (247), 247ra101-247ra101, 2014
3252014
Engineering NK cells modified with an EGFRvIII-specific chimeric antigen receptor to overexpress CXCR4 improves immunotherapy of CXCL12/SDF-1α-secreting glioblastoma
N Müller, S Michen, S Tietze, K Töpfer, A Schulte, K Lamszus, M Schmitz, ...
Journal of Immunotherapy 38 (5), 197-210, 2015
2282015
Regulated shedding of transmembrane chemokines by the disintegrin and metalloproteinase 10 facilitates detachment of adherent leukocytes
C Hundhausen, A Schulte, B Schulz, MG Andrzejewski, N Schwarz, ...
The Journal of Immunology 178 (12), 8064-8072, 2007
2152007
Enhanced expression and shedding of the transmembrane chemokine CXCL16 by reactive astrocytes and glioma cells
A Ludwig, A Schulte, C Schnack, C Hundhausen, K Reiss, N Brodway, ...
Journal of neurochemistry 93 (5), 1293-1303, 2005
1522005
Hypoxia and oxygenation induce a metabolic switch between pentose phosphate pathway and glycolysis in glioma stem-like cells
A Kathagen, A Schulte, G Balcke, HS Phillips, T Martens, J Matschke, ...
Acta neuropathologica 126, 763-780, 2013
1322013
Glycolysis and the pentose phosphate pathway are differentially associated with the dichotomous regulation of glioblastoma cell migration versus proliferation
A Kathagen-Buhmann, A Schulte, J Weller, M Holz, C Herold-Mende, ...
Neuro-oncology 18 (9), 1219-1229, 2016
1282016
A distinct subset of glioma cell lines with stem cell‐like properties reflects the transcriptional phenotype of glioblastomas and overexpresses CXCR4 as therapeutic target
A Schulte, HS Günther, HS Phillips, D Kemming, T Martens, S Kharbanda, ...
Glia 59 (4), 590-602, 2011
1232011
Functional dissection of the epidermal growth factor receptor epitopes targeted by panitumumab and cetuximab
M Voigt, F Braig, M Göthel, A Schulte, K Lamszus, C Bokemeyer, M Binder
Neoplasia 14 (11), 1023-IN3, 2012
1222012
A novel fluorescent pH probe for expression in plants
A Schulte, I Lorenzen, M Böttcher, C Plieth
Plant methods 2, 1-13, 2006
1122006
Sequential processing of the transmembrane chemokines CX3CL1 and CXCL16 by α-and γ-secretases
A Schulte, B Schulz, MG Andrzejewski, C Hundhausen, S Mletzko, ...
Biochemical and biophysical research communications 358 (1), 233-240, 2007
1052007
Constitutive expression and regulated release of the transmembrane chemokine CXCL16 in human and murine skin
F Scholz, A Schulte, F Adamski, C Hundhausen, J Mittag, A Schwarz, ...
Journal of Investigative Dermatology 127 (6), 1444-1455, 2007
962007
Erlotinib resistance in EGFR-amplified glioblastoma cells is associated with upregulation of EGFRvIII and PI3Kp110δ
A Schulte, K Liffers, A Kathagen, S Riethdorf, S Zapf, A Merlo, K Kolbe, ...
Neuro-oncology 15 (10), 1289-1301, 2013
882013
Glioblastoma stem–like cell lines with either maintenance or loss of high-level EGFR amplification, generated via modulation of ligand concentration
A Schulte, HS Günther, T Martens, S Zapf, S Riethdorf, C Wülfing, ...
Clinical Cancer Research 18 (7), 1901-1913, 2012
822012
Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer
BM Braig F, März M, Schieferdecker A, Schulte A, Voigt M, Stein A, Grob T ...
Oncotarget 6 (14), 2015
662015
Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer
F Braig, M März, A Schieferdecker, A Schulte, M Voigt, A Stein, T Grob, ...
Oncotarget, 2015
662015
Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies
M Preukschas, C Hagel, A Schulte, K Weber, K Lamszus, H Sievert, ...
Public Library of Science 7 (8), e43468, 2012
662012
RON receptor tyrosine kinase in human gliomas: expression, function, and identification of a novel soluble splice variant
C Eckerich, A Schulte, T Martens, S Zapf, M Westphal, K Lamszus
Journal of neurochemistry 109 (4), 969-980, 2009
592009
EGFR amplification and glioblastoma stem-like cells
K Liffers, K Lamszus, A Schulte, A Schulte
Stem Cells International, 2015
552015
PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression
I Hohensee, HN Chuang, A Grottke, S Werner, A Schulte, S Horn, ...
Oncotarget 8 (4), 6155, 2017
432017
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Artículos 1–20