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Kathryn J Moore
Kathryn J Moore
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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
P Duewell, H Kono, KJ Rayner, CM Sirois, G Vladimer, FG Bauernfeind, ...
Nature 464 (7293), 1357-1361, 2010
39582010
Macrophages in the pathogenesis of atherosclerosis
KJ Moore, I Tabas
Cell 145 (3), 341-355, 2011
29032011
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
A Halle, V Hornung, GC Petzold, CR Stewart, BG Monks, T Reinheckel, ...
Nature immunology 9 (8), 857-865, 2008
26812008
PPARγ is required for the differentiation of adipose tissue in vivo and in vitro
ED Rosen, P Sarraf, AE Troy, G Bradwin, K Moore, DS Milstone, ...
Molecular cell 4 (4), 611-617, 1999
26021999
Macrophages in atherosclerosis: a dynamic balance
KJ Moore, FJ Sheedy, EA Fisher
Nature Reviews Immunology 13 (10), 709-721, 2013
25582013
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
CR Stewart, LM Stuart, K Wilkinson, JM Van Gils, J Deng, A Halle, ...
Nature immunology 11 (2), 155-161, 2010
16872010
MiR-33 contributes to the regulation of cholesterol homeostasis
KJ Rayner, Y Suárez, A Dávalos, S Parathath, ML Fitzgerald, N Tamehiro, ...
science 328 (5985), 1570-1573, 2010
14422010
Scavenger receptors class AI/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages
VV Kunjathoor, M Febbraio, EA Podrez, KJ Moore, L Andersson, S Koehn, ...
Journal of Biological Chemistry 277 (51), 49982-49988, 2002
12372002
CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation
FJ Sheedy, A Grebe, KJ Rayner, P Kalantari, B Ramkhelawon, ...
Nature immunology 14 (8), 812-820, 2013
9232013
Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides
KJ Rayner, CC Esau, FN Hussain, AL McDaniel, SM Marshall, ...
Nature 478 (7369), 404-407, 2011
8242011
Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways
H Björkbacka, VV Kunjathoor, KJ Moore, S Koehn, CM Ordija, MA Lee, ...
Nature medicine 10 (4), 416-421, 2004
8162004
Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis
KJ Rayner, FJ Sheedy, CC Esau, FN Hussain, RE Temel, S Parathath, ...
The Journal of clinical investigation 121 (7), 2921-2931, 2011
8062011
Scavenger receptors in atherosclerosis: beyond lipid uptake
KJ Moore, MW Freeman
Arteriosclerosis, thrombosis, and vascular biology 26 (8), 1702-1711, 2006
7372006
miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling
A Dávalos, L Goedeke, P Smibert, CM Ramírez, NP Warrier, U Andreo, ...
Proceedings of the National Academy of Sciences 108 (22), 9232-9237, 2011
7342011
The role of PPAR-γ in macrophage differentiation and cholesterol uptake
KJ Moore, ED Rosen, ML Fitzgerald, F Randow, LP Andersson, ...
Nature medicine 7 (1), 41-47, 2001
6622001
MicroRNA regulation of atherosclerosis
MW Feinberg, KJ Moore
Circulation research 118 (4), 703-720, 2016
6262016
CD36 mediates the innate host response to β-amyloid
JB El Khoury, KJ Moore, TK Means, J Leung, K Terada, M Toft, ...
The Journal of experimental medicine 197 (12), 1657-1666, 2003
5792003
Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress
TA Seimon, MJ Nadolski, X Liao, J Magallon, M Nguyen, NT Feric, ...
Cell metabolism 12 (5), 467-482, 2010
5412010
Response to Staphylococcus aureus requires CD36-mediated phagocytosis triggered by the COOH-terminal cytoplasmic domain
LM Stuart, J Deng, JM Silver, K Takahashi, AA Tseng, EJ Hennessy, ...
The Journal of cell biology 170 (3), 477-485, 2005
5082005
Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice
KJ Moore, VV Kunjathoor, SL Koehn, JJ Manning, AA Tseng, JM Silver, ...
The Journal of clinical investigation 115 (8), 2192-2201, 2005
4702005
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