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Jorke Willemse
Jorke Willemse
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Decellularization of whole human liver grafts using controlled perfusion for transplantable organ bioscaffolds
MMA Verstegen, J Willemse, S Van Den Hoek, GJ Kremers, TM Luider, ...
Stem cells and development 26 (18), 1304-1315, 2017
922017
Fast, robust and effective decellularization of whole human livers using mild detergents and pressure controlled perfusion
J Willemse, MMA Verstegen, A Vermeulen, IJ Schurink, HP Roest, ...
Materials Science and Engineering: C 108, 110200, 2020
762020
From organoids to organs: Bioengineering liver grafts from hepatic stem cells and matrix
J Willemse, R Lieshout, LJW van der Laan, MMA Verstegen
Best practice & research Clinical gastroenterology 31 (2), 151-159, 2017
472017
Hydrogels derived from decellularized liver tissue support the growth and differentiation of cholangiocyte organoids
J Willemse, G van Tienderen, E van Hengel, I Schurink, D van der Ven, ...
Biomaterials 284, 121473, 2022
382022
Scaffolds obtained from decellularized human extrahepatic bile ducts support organoids to establish functional biliary tissue in a dish
J Willemse, FJM Roos, IJ Voogt, IJ Schurink, M Bijvelds, HR de Jonge, ...
Biotechnology and Bioengineering 118 (2), 836-851, 2021
302021
Human branching cholangiocyte organoids recapitulate functional bile duct formation
FJM Roos, GS van Tienderen, H Wu, I Bordeu, D Vinke, LM Albarinos, ...
Cell Stem Cell 29 (5), 776-794. e13, 2022
202022
Extracellular matrix drives tumor organoids toward desmoplastic matrix deposition and mesenchymal transition
GS van Tienderen, O Rosmark, R Lieshout, J Willemse, F de Weijer, ...
Acta biomaterialia 158, 115-131, 2023
192023
Design by nature: emerging applications of native liver extracellular matrix for cholangiocyte organoid-based regenerative medicine
J Willemse, LJW van der Laan, J de Jonge, MMA Verstegen
Bioengineering 9 (3), 110, 2022
182022
Cholangiocyte organoids from human bile retain a local phenotype and can repopulate bile ducts in vitro
FJM Roos, H Wu, J Willemse, R Lieshout, LAM Albarinos, YY Kan, ...
Clinical and translational medicine 11 (12), e566, 2021
152021
A proof of concept study on real-time LiMAx CYP1A2 liver function assessment of donor grafts during normothermic machine perfusion
IJ Schurink, JE de Haan, J Willemse, M Mueller, M Doukas, H Roest, ...
Scientific Reports 11 (1), 23444, 2021
122021
Tumor decellularization reveals proteomic and mechanical characteristics of the extracellular matrix of primary liver cancer
GS van Tienderen, J Conboy, I Muntz, J Willemse, J Tieleman, K Monfils, ...
Biomaterials Advances 146, 213289, 2023
102023
Long‐Term Perfusion of the Liver Outside the Body: Warming Up for Ex Vivo Therapies?
IJ Schurink, J Willemse, MMA Verstegen, LJW van Der Laan, J de Jonge
Hepatology (Baltimore, Md.) 72 (4), 1485, 2020
52020
Scalable production of size-controlled cholangiocyte and cholangiocarcinoma organoids within liver extracellular matrix-containing microcapsules
GS van Tienderen, J Willemse, B van Loo, EVA van Hengel, J de Jonge, ...
Cells 11 (22), 3657, 2022
32022
Towards engineering human extrahepatic bile ducts from ductal extracellular matrix and biliary organoids
J Willemse, MMA Verstegen, I Voogt, FJM Roos, LJW van der Laan, ...
Transplantation 103 (8), 272-272, 2019
12019
Design by nature: creating a clinical grade hydrogel from liver extracellular matrix to improve culture expansion and differentiation of human liver organoids
J Willemse, D Van der Ven, J de Jonge, LJW Van der Laan, ...
Transplantation 103 (8), 16-16, 2019
12019
Towards graft engineering using decellularized porcine liver scaffolds and recellularization with human liver organoids
J Willemse, MMA Verstegen, LJW van der Laan, J de Jonge
Transplantation 102, 6-6, 2018
12018
Endothelial Cell Replacement of Human Veins, Modeling Vascular Repair and Endothelial Cell Chimerism
H Tejeda-Mora, Y den Hartog, IJ Schurink, MMA Verstegen, J de Jonge, ...
Stem Cells and Development 33 (1-2), 27-42, 2024
2024
Decellularized Tissue-Derived Materials for Organoid Culture
J Willemse, MMA Verstegen
Handbook of the Extracellular Matrix: Biologically-Derived Materials, 1-13, 2023
2023
315.17: Functional Recellularized Patient Derived Endothelium; A Human Vascular Graft Approach
HT Mora, J Willemse, Y den Hartog, I Schurink, MMA Verstegen, ...
Transplantation 106 (9S), S242, 2022
2022
Cross-talk between cholangiocarcinoma cells and extracellular microenvironment drives desmoplastic matrix deposition
G van Tienderen, O Rosmark, R Lieshout, J Willemse, F de Weijer, ...
Journal of Hepatology 77, S644, 2022
2022
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