| Autoantibodies against type I IFNs in patients with life-threatening COVID-19 P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, ... Science 370 (6515), 2020 | 2210 | 2020 |
| Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez, J Chen, M Ogishi, ... Science 370 (6515), 2020 | 1911 | 2020 |
| Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery F Zhu, Z Shi, C Qin, L Tao, X Liu, F Xu, L Zhang, Y Song, X Liu, J Zhang, ... Nucleic acids research 40 (D1), D1128-D1136, 2012 | 527 | 2012 |
| Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics YH Li, CY Yu, XX Li, P Zhang, J Tang, Q Yang, T Fu, X Zhang, X Cui, G Tu, ... Nucleic acids research 46 (D1), D1121-D1127, 2018 | 472 | 2018 |
| X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19 T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ... Science Immunology 6 (62), 2021 | 276 | 2021 |
| NPASS: natural product activity and species source database for natural product research, discovery and tool development X Zeng, P Zhang, W He, C Qin, S Chen, L Tao, Y Wang, Y Tan, D Gao, ... Nucleic acids research 46 (D1), D1217-D1222, 2018 | 184 | 2018 |
| Human genetic and immunological determinants of critical COVID-19 pneumonia Q Zhang, P Bastard, A Cobat, JL Casanova Nature, 1-15, 2022 | 169 | 2022 |
| Therapeutic target database update 2014: a resource for targeted therapeutics C Qin, C Zhang, F Zhu, F Xu, SY Chen, P Zhang, YH Li, SY Yang, YQ Wei, ... Nucleic acids research 42 (D1), D1118-D1123, 2014 | 143 | 2014 |
| Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19 MGP van der Wijst, SE Vazquez, GC Hartoularos, P Bastard, T Grant, ... Science translational medicine, 2021 | 137 | 2021 |
| Life-Threatening COVID-19: Defective Interferons Unleash Excessive Inflammation Q Zhang, P Bastard, A Bolze, E Jouanguy, SY Zhang, CHG Effort, A Cobat, ... Med 1 (1), 14-20, 2020 | 128 | 2020 |
| SARS-CoV-2–related MIS-C: A key to the viral and genetic causes of Kawasaki disease? V Sancho-Shimizu, P Brodin, A Cobat, CM Biggs, J Toubiana, CL Lucas, ... Journal of Experimental Medicine 218 (6), e20210446, 2021 | 120 | 2021 |
| SVM-Prot 2016: a web-server for machine learning prediction of protein functional families from sequence irrespective of similarity YH Li, JY Xu, L Tao, XF Li, S Li, X Zeng, SY Chen, P Zhang, C Qin, ... PloS one 11 (8), 2016 | 117 | 2016 |
| Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis FG Lafaille, O Harschnitz, YS Lee, P Zhang, ML Hasek, G Kerner, Y Itan, ... Nature Medicine 25 (12), 1873-1884, 2019 | 87 | 2019 |
| Human T-bet governs innate and innate-like adaptive IFN-γ immunity against mycobacteria R Yang, F Mele, L Worley, D Langlais, J Rosain, I Benhsaien, H Elarabi, ... Cell, 2020 | 81 | 2020 |
| Recent progresses in the exploration of machine learning methods as in-silico ADME prediction tools L Tao, P Zhang, C Qin, SY Chen, C Zhang, Z Chen, F Zhu, SY Yang, ... Advanced Drug Delivery Reviews 86, 83-100, 2015 | 75 | 2015 |
| Herpes simplex encephalitis in a patient with a distinctive form of inherited IFNAR1 deficiency P Bastard, J Manry, J Chen, J Rosain, Y Seeleuthner, O AbuZaitun, ... The Journal of Clinical Investigation, 2020 | 69 | 2020 |
| CMAUP: a database of collective molecular activities of useful plants X Zeng, P Zhang, Y Wang, C Qin, S Chen, W He, L Tao, Y Tan, D Gao, ... Nucleic acids research 47 (D1), D1118-D1127, 2019 | 67 | 2019 |
| TLR3 controls constitutive IFN-b antiviral immunity in human fibroblasts and cortical neurons D Gao, MJ Ciancanelli, P Zhang, O Harschnitz, V Bondet, M Hasek, ... The Journal of Clinical Investigation, 2020 | 59 | 2020 |
| Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child M Ogishi, R Yang, C Aytekin, D Langlais, M Bourgey, T Khan, F Al Ali, ... Nature Medicine, 1-9, 2021 | 58 | 2021 |
| A protein network descriptor server and its use in studying protein, disease, metabolic and drug targeted networks P Zhang, L Tao, X Zeng, C Qin, S Chen, F Zhu, Z Li, Y Jiang, W Chen, ... Briefings in bioinformatics 18 (6), 1057-1070, 2017 | 49 | 2017 |
Yu Zong ChenProfessor Department of Pharmacy National University of SingaporeDirección de correo verificada de nus.edu.sg
