Francesco Iorio

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Mathew GarnettWellcome Sanger InstituteDirección de correo verificada de sanger.ac.uk
Julio Saez RodriguezHeidelberg UniversityDirección de correo verificada de uni-heidelberg.de
Diego di BernardoDept. Chemical, Materials and Industrial Production Engineering, Univ. Federico II of Naples & TIGEMDirección de correo verificada de tigem.it
Ultan McDermottFaculty, Wellcome Trust Sanger InstituteDirección de correo verificada de sanger.ac.uk
Fiona M BehanDirector, GSKDirección de correo verificada de gsk.com
Roberto TAGLIAFERRINeurone Lab - Disa Mis - University of SalernoDirección de correo verificada de unisa.it
Kosuke YusaProfessor, Kyoto UniversityDirección de correo verificada de infront.kyoto-u.ac.jp
Emanuel GonçalvesINESC-ID & IST - Universidade de LisboaDirección de correo verificada de tecnico.ulisboa.pt
Euan StronachGSKDirección de correo verificada de gsk.com
Michael P. MendenAssociate Professor, University of Melbourne, Department of Biochemistry and PharmacologyDirección de correo verificada de helmholtz-muenchen.de
Graham Robert BignellSenior Staff Scientist, Wellcome Trust Sanger InstituteDirección de correo verificada de sanger.ac.uk
Rita SantosComputational Biology, GSKDirección de correo verificada de ebi.ac.uk
Livio TrusolinoProfessor, University of Torino School of Medicine, ItalyDirección de correo verificada de ircc.it
Andrea BertottiUniversity of Torino - School of MedicineDirección de correo verificada de ircc.it
Luz Garcia-AlonsoPrincipal Bioinformatician at Wellcome Sanger InstituteDirección de correo verificada de sanger.ac.uk
Nicola Brunetti-PierriFederico II UniversityDirección de correo verificada de unina.it
Philippe SanseauGSKDirección de correo verificada de gsk.com
Munir PirmohamedUniversity of LiverpoolDirección de correo verificada de liv.ac.uk
Leopold PartsFaculty at Wellcome Sanger Institute; Senior Researcher (part-time) at University of TartuDirección de correo verificada de sanger.ac.uk
Felicity AllenWellcome Sanger InstituteDirección de correo verificada de sanger.ac.uk

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Francesco Iorio

Human Technopole

Dirección de correo verificada de fht.org - Página principal

computational functional genomics of cancer


Título Ordenar por citas Ordenar por año Ordenar por título	Citado por Citado por	Año
Drug repurposing: progress, challenges and recommendations S Pushpakom, F Iorio, PA Eyers, KJ Escott, S Hopper, A Wells, A Doig, ... Nature reviews Drug discovery 18 (1), 41-58, 2019	3101	2019
Systematic identification of genomic markers of drug sensitivity in cancer cells MJ Garnett, EJ Edelman, SJ Heidorn, CD Greenman, A Dastur, KW Lau, ... Nature 483 (7391), 570-575, 2012	2475	2012
Prospective derivation of a living organoid biobank of colorectal cancer patients M Van de Wetering, HE Francies, JM Francis, G Bounova, F Iorio, A Pronk, ... Cell 161 (4), 933-945, 2015	1959	2015
A landscape of pharmacogenomic interactions in cancer F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ... Cell 166 (3), 740-754, 2016	1588	2016
Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens FM Behan, F Iorio, G Picco, E Gonçalves, CM Beaver, G Migliardi, ... Nature 568 (7753), 511-516, 2019	930	2019
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma N Bolli, H Avet-Loiseau, DC Wedge, P Van Loo, LB Alexandrov, ... Nature communications 5 (1), 2997, 2014	928	2014
Discovery of drug mode of action and drug repositioning from transcriptional responses F Iorio, R Bosotti, E Scacheri, V Belcastro, P Mithbaokar, R Ferriero, ... Proceedings of the National Academy of Sciences 107 (33), 14621-14626, 2010	847	2010
A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia K Tzelepis, H Koike-Yusa, E De Braekeleer, Y Li, E Metzakopian, ... Cell reports 17 (4), 1193-1205, 2016	586	2016
Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties MP Menden, F Iorio, M Garnett, U McDermott, CH Benes, PJ Ballester, ... PLoS one 8 (4), e61318, 2013	509	2013
A yeast synthetic network for in vivo assessment of reverse-engineering and modeling approaches I Cantone, L Marucci, F Iorio, MA Ricci, V Belcastro, M Bansal, S Santini, ... Cell 137 (1), 172-181, 2009	422	2009
Characterizing mutational signatures in human cancer cell lines reveals episodic APOBEC mutagenesis M Petljak, LB Alexandrov, JS Brammeld, S Price, DC Wedge, ... Cell 176 (6), 1282-1294. e20, 2019	323	2019
Pharmacogenomic agreement between two cancer cell line data sets Cancer Cell Line Encyclopedia Consortium, ... Nature 528 (7580), 84-87, 2015	275	2015
Transcriptional data: a new gateway to drug repositioning? F Iorio, T Rittman, H Ge, M Menden, J Saez-Rodriguez Drug discovery today 18 (7-8), 350-357, 2013	254	2013
Transcription factor activities enhance markers of drug sensitivity in cancer L Garcia-Alonso, F Iorio, A Matchan, N Fonseca, P Jaaks, G Peat, ... Cancer research 78 (3), 769-780, 2018	166	2018
Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets JM Dempster, C Pacini, S Pantel, FM Behan, T Green, J Krill-Burger, ... Nature communications 10 (1), 5817, 2019	152	2019
BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model D Perna, FA Karreth, AG Rust, PA Perez-Mancera, M Rashid, F Iorio, ... Proceedings of the National Academy of Sciences 112 (6), E536-E545, 2015	149	2015
Integrated cross-study datasets of genetic dependencies in cancer C Pacini, JM Dempster, I Boyle, E Gonçalves, H Najgebauer, E Karakoc, ... Nature communications 12 (1), 1661, 2021	143	2021
Hemopoietic-specific Sf3b1-K700E knock-in mice display the splicing defect seen in human MDS but develop anemia without ring sideroblasts A Mupo, M Seiler, V Sathiaseelan, A Pance, Y Yang, AA Agrawal, F Iorio, ... Leukemia 31 (3), 720-727, 2017	133	2017
Transcriptional gene network inference from a massive dataset elucidates transcriptome organization and gene function V Belcastro, V Siciliano, F Gregoretti, P Mithbaokar, G Dharmalingam, ... Nucleic acids research 39 (20), 8677-8688, 2011	120	2011
Identifying network of drug mode of action by gene expression profiling F Iorio, R Tagliaferri, D Bernardo Journal of Computational Biology 16 (2), 241-251, 2009	117	2009

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