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Christopher Lengner
Christopher Lengner
Verified email at vet.upenn.edu
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Year
Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression
T Gaur, CJ Lengner, H Hovhannisyan, RA Bhat, PVN Bodine, BS Komm, ...
Journal of Biological Chemistry 280 (39), 33132-33140, 2005
13952005
Direct cell reprogramming is a stochastic process amenable to acceleration
J Hanna, K Saha, B Pando, J Van Zon, CJ Lengner, MP Creyghton, ...
Nature 462 (7273), 595-601, 2009
12212009
Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency
J Hanna, S Markoulaki, P Schorderet, BW Carey, C Beard, M Wernig, ...
cell 133 (2), 250-264, 2008
11262008
Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells
T Brambrink, R Foreman, GG Welstead, CJ Lengner, M Wernig, H Suh, ...
Cell stem cell 2 (2), 151-159, 2008
10752008
Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs
J Hanna, AW Cheng, K Saha, J Kim, CJ Lengner, F Soldner, JP Cassady, ...
Proceedings of the National Academy of Sciences 107 (20), 9222-9227, 2010
10112010
A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types
M Wernig, CJ Lengner, J Hanna, MA Lodato, E Steine, R Foreman, ...
Nature biotechnology 26 (8), 916-924, 2008
5742008
Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors
JB Lian, A Javed, SK Zaidi, C Lengner, M Montecino, AJ Van Wijnen, ...
Critical Reviews™ in Eukaryotic Gene Expression 14 (1&2), 2004
5542004
Networks and hubs for the transcriptional control of osteoblastogenesis
JB Lian, GS Stein, A Javed, AJ Van Wijnen, JL Stein, M Montecino, ...
Reviews in Endocrine and Metabolic Disorders 7, 1-16, 2006
5232006
Oct4 expression is not required for mouse somatic stem cell self-renewal
CJ Lengner, FD Camargo, K Hochedlinger, GG Welstead, S Zaidi, ...
Cell stem cell 1 (4), 403-415, 2007
5042007
Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations
CJ Lengner, AA Gimelbrant, JA Erwin, AW Cheng, MG Guenther, ...
Cell 141 (5), 872-883, 2010
4562010
Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia
MG Kharas, CJ Lengner, F Al-Shahrour, L Bullinger, B Ball, S Zaidi, ...
Nature medicine 16 (8), 903-908, 2010
4092010
Metastable pluripotent states in NOD-mouse-derived ESCs
J Hanna, S Markoulaki, M Mitalipova, AW Cheng, JP Cassady, J Staerk, ...
Cell stem cell 4 (6), 513-524, 2009
4072009
Functional integration of dopaminergic neurons directly converted from mouse fibroblasts
J Kim, SC Su, H Wang, AW Cheng, JP Cassady, MA Lodato, CJ Lengner, ...
Cell stem cell 9 (5), 413-419, 2011
3122011
Osteoblast differentiation and skeletal development are regulated by Mdm2–p53 signaling
CJ Lengner, HA Steinman, J Gagnon, TW Smith, JE Henderson, ...
The Journal of cell biology 172 (6), 909-921, 2006
3022006
Modeling G2019S-LRRK2 sporadic Parkinson's disease in 3D midbrain organoids
H Kim, HJ Park, H Choi, Y Chang, H Park, J Shin, J Kim, CJ Lengner, ...
Stem Cell Reports 12 (3), 518-531, 2019
2602019
DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function
Q Yu, YV Katlinskaya, CJ Carbone, B Zhao, KV Katlinski, H Zheng, ...
Cell reports 11 (5), 785-797, 2015
2412015
In vivo neuronal gene editing via CRISPR–Cas9 amphiphilic nanocomplexes alleviates deficits in mouse models of Alzheimer’s disease
H Park, J Oh, G Shim, B Cho, Y Chang, S Kim, S Baek, H Kim, J Shin, ...
Nature neuroscience 22 (4), 524-528, 2019
2112019
Single-cell lineage tracing of metastatic cancer reveals selection of hybrid EMT states
KP Simeonov, CN Byrns, ML Clark, RJ Norgard, B Martin, BZ Stanger, ...
Cancer cell 39 (8), 1150-1162. e9, 2021
1882021
MiR-31 promotes mammary stem cell expansion and breast tumorigenesis by suppressing Wnt signaling antagonists
C Lv, F Li, X Li, Y Tian, Y Zhang, X Sheng, Y Song, Q Meng, S Yuan, ...
Nature communications 8 (1), 1036, 2017
1652017
Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs
SM Park, RP Deering, Y Lu, P Tivnan, S Lianoglou, F Al-Shahrour, ...
Journal of Experimental Medicine 211 (1), 71-87, 2014
1612014
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