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Elgene Lim
Elgene Lim
UNSW, Garvan Institute, St Vincent's Hospital
Dirección de correo verificada de garvan.org.au - Página principal
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Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
E Lim, F Vaillant, D Wu, NC Forrest, B Pal, AH Hart, ML Asselin-Labat, ...
Nature medicine 15 (8), 907-913, 2009
16222009
XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway
X Chen, D Iliopoulos, Q Zhang, Q Tang, MB Greenblatt, M Hatziapostolou, ...
Nature 508 (7494), 103-107, 2014
8302014
EMT, cell plasticity and metastasis
CL Chaffer, BP San Juan, E Lim, RA Weinberg
Cancer and Metastasis Reviews 35, 645-654, 2016
8282016
A single-cell and spatially resolved atlas of human breast cancers
SZ Wu, G Al-Eryani, DL Roden, S Junankar, K Harvey, A Andersson, ...
Nature genetics 53 (9), 1334-1347, 2021
6072021
ROAST: rotation gene set tests for complex microarray experiments
D Wu, E Lim, F Vaillant, ML Asselin-Labat, JE Visvader, GK Smyth
Bioinformatics 26 (17), 2176-2182, 2010
5702010
Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways
E Lim, D Wu, B Pal, T Bouras, ML Asselin-Labat, F Vaillant, H Yagita, ...
Breast Cancer Research 12, 1-14, 2010
4722010
Targeting androgen receptor in estrogen receptor-negative breast cancer
M Ni, Y Chen, E Lim, H Wimberly, ST Bailey, Y Imai, DL Rimm, XS Liu, ...
Cancer cell 20 (1), 119-131, 2011
4342011
CDK7-dependent transcriptional addiction in triple-negative breast cancer
Y Wang, T Zhang, N Kwiatkowski, BJ Abraham, TI Lee, S Xie, H Yuzugullu, ...
Cell 163 (1), 174-186, 2015
4192015
Clinical overview of MDM2/X-targeted therapies
A Burgess, KM Chia, S Haupt, D Thomas, Y Haupt, E Lim
Frontiers in oncology 6, 7, 2016
3772016
Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer
AS Cazet, MN Hui, BL Elsworth, SZ Wu, D Roden, CL Chan, JN Skhinas, ...
Nature communications 9 (1), 2897, 2018
3582018
Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells
WL Tam, H Lu, J Buikhuisen, BS Soh, E Lim, F Reinhardt, ZJ Wu, JA Krall, ...
Cancer cell 24 (3), 347-364, 2013
3512013
Adjuvant abemaciclib combined with endocrine therapy for high-risk early breast cancer: updated efficacy and Ki-67 analysis from the monarchE study
N Harbeck, P Rastogi, M Martin, SM Tolaney, ZM Shao, PA Fasching, ...
Annals of Oncology 32 (12), 1571-1581, 2021
2962021
CDK12 inhibition reverses de novo and acquired PARP inhibitor resistance in BRCA wild-type and mutated models of triple-negative breast cancer
SF Johnson, C Cruz, AK Greifenberg, S Dust, DG Stover, D Chi, ...
Cell reports 17 (9), 2367-2381, 2016
2622016
Stromal cell diversity associated with immune evasion in human triple‐negative breast cancer
SZ Wu, DL Roden, C Wang, H Holliday, K Harvey, AS Cazet, KJ Murphy, ...
The EMBO journal 39 (19), e104063, 2020
2562020
Sensitization of BCL-2–expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737
SR Oakes, F Vaillant, E Lim, L Lee, K Breslin, F Feleppa, S Deb, ...
Proceedings of the National Academy of Sciences 109 (8), 2766-2771, 2012
2212012
The natural history of hormone receptor-positive breast cancer
MD Elgene Lim, O Metzger-Filho, EP Winer
Oncology 26 (8), 688, 2012
1892012
Targeting CDK2 in cancer: challenges and opportunities for therapy
S Tadesse, AT Anshabo, N Portman, E Lim, W Tilley, CE Caldon, S Wang
Drug discovery today 25 (2), 406-413, 2020
1752020
PARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination–mediated DNA repair
Y Hu, SA Petit, SB Ficarro, KJ Toomire, A Xie, E Lim, SA Cao, E Park, ...
Cancer discovery 4 (12), 1430-1447, 2014
1652014
IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel
ZN Wee, SMJM Yatim, VK Kohlbauer, M Feng, JY Goh, Y Bao, PL Lee, ...
Nature communications 6 (1), 8746, 2015
1612015
Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling
P Roswall, M Bocci, M Bartoschek, H Li, G Kristiansen, S Jansson, S Lehn, ...
Nature medicine 24 (4), 463-473, 2018
1572018
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