Elgene Lim
Elgene Lim
UNSW, Garvan Institute, St Vincent's Hospital
Dirección de correo verificada de - Página principal
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Citado por
Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
E Lim, F Vaillant, D Wu, NC Forrest, B Pal, AH Hart, ML Asselin-Labat, ...
Nature medicine 15 (8), 907-913, 2009
XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway
X Chen, D Iliopoulos, Q Zhang, Q Tang, MB Greenblatt, M Hatziapostolou, ...
Nature 508 (7494), 103-107, 2014
EMT, cell plasticity and metastasis
CL Chaffer, BP San Juan, E Lim, RA Weinberg
Cancer and Metastasis Reviews 35, 645-654, 2016
A single-cell and spatially resolved atlas of human breast cancers
SZ Wu, G Al-Eryani, DL Roden, S Junankar, K Harvey, A Andersson, ...
Nature genetics 53 (9), 1334-1347, 2021
ROAST: rotation gene set tests for complex microarray experiments
D Wu, E Lim, F Vaillant, ML Asselin-Labat, JE Visvader, GK Smyth
Bioinformatics 26 (17), 2176-2182, 2010
Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways
E Lim, D Wu, B Pal, T Bouras, ML Asselin-Labat, F Vaillant, H Yagita, ...
Breast Cancer Research 12, 1-14, 2010
Targeting androgen receptor in estrogen receptor-negative breast cancer
M Ni, Y Chen, E Lim, H Wimberly, ST Bailey, Y Imai, DL Rimm, XS Liu, ...
Cancer cell 20 (1), 119-131, 2011
CDK7-dependent transcriptional addiction in triple-negative breast cancer
Y Wang, T Zhang, N Kwiatkowski, BJ Abraham, TI Lee, S Xie, H Yuzugullu, ...
Cell 163 (1), 174-186, 2015
Clinical overview of MDM2/X-targeted therapies
A Burgess, KM Chia, S Haupt, D Thomas, Y Haupt, E Lim
Frontiers in oncology 6, 7, 2016
Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer
AS Cazet, MN Hui, BL Elsworth, SZ Wu, D Roden, CL Chan, JN Skhinas, ...
Nature communications 9 (1), 2897, 2018
Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells
WL Tam, H Lu, J Buikhuisen, BS Soh, E Lim, F Reinhardt, ZJ Wu, JA Krall, ...
Cancer cell 24 (3), 347-364, 2013
Adjuvant abemaciclib combined with endocrine therapy for high-risk early breast cancer: updated efficacy and Ki-67 analysis from the monarchE study
N Harbeck, P Rastogi, M Martin, SM Tolaney, ZM Shao, PA Fasching, ...
Annals of Oncology 32 (12), 1571-1581, 2021
CDK12 inhibition reverses de novo and acquired PARP inhibitor resistance in BRCA wild-type and mutated models of triple-negative breast cancer
SF Johnson, C Cruz, AK Greifenberg, S Dust, DG Stover, D Chi, ...
Cell reports 17 (9), 2367-2381, 2016
Stromal cell diversity associated with immune evasion in human triple‐negative breast cancer
SZ Wu, DL Roden, C Wang, H Holliday, K Harvey, AS Cazet, KJ Murphy, ...
The EMBO journal 39 (19), e104063, 2020
Sensitization of BCL-2–expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737
SR Oakes, F Vaillant, E Lim, L Lee, K Breslin, F Feleppa, S Deb, ...
Proceedings of the National Academy of Sciences 109 (8), 2766-2771, 2012
The natural history of hormone receptor-positive breast cancer
MD Elgene Lim, O Metzger-Filho, EP Winer
Oncology 26 (8), 688, 2012
Targeting CDK2 in cancer: challenges and opportunities for therapy
S Tadesse, AT Anshabo, N Portman, E Lim, W Tilley, CE Caldon, S Wang
Drug discovery today 25 (2), 406-413, 2020
PARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination–mediated DNA repair
Y Hu, SA Petit, SB Ficarro, KJ Toomire, A Xie, E Lim, SA Cao, E Park, ...
Cancer discovery 4 (12), 1430-1447, 2014
IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel
ZN Wee, SMJM Yatim, VK Kohlbauer, M Feng, JY Goh, Y Bao, PL Lee, ...
Nature communications 6 (1), 8746, 2015
Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling
P Roswall, M Bocci, M Bartoschek, H Li, G Kristiansen, S Jansson, S Lehn, ...
Nature medicine 24 (4), 463-473, 2018
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