Computing complex metabolic intervention strategies using constrained minimal cut sets O Hädicke, S Klamt Metabolic engineering 13 (2), 204-213, 2011 | 142 | 2011 |
CASOP: a computational approach for strain optimization aiming at high productivity O Hädicke, S Klamt Journal of biotechnology 147 (2), 88-101, 2010 | 104 | 2010 |
Use of CellNetAnalyzer in biotechnology and metabolic engineering A von Kamp, S Thiele, O Hädicke, S Klamt Journal of biotechnology 261, 221-228, 2017 | 98 | 2017 |
In silico profiling of Escherichia coli and Saccharomyces cerevisiae as terpenoid factories E Gruchattka, O Hädicke, S Klamt, V Schütz, O Kayser Microbial cell factories 12, 1-18, 2013 | 97 | 2013 |
Metabolic network modeling of redox balancing and biohydrogen production in purple nonsulfur bacteria O Hädicke, H Grammel, S Klamt BMC systems biology 5, 1-18, 2011 | 97 | 2011 |
When do two‐stage processes outperform one‐stage processes? S Klamt, R Mahadevan, O Hädicke Biotechnology journal 13 (2), 1700539, 2018 | 65 | 2018 |
EColiCore2: a reference network model of the central metabolism of Escherichia coli and relationships to its genome-scale parent model O Hädicke, S Klamt Scientific Reports 7 (1), 39647, 2017 | 64 | 2017 |
OptMDFpathway: Identification of metabolic pathways with maximal thermodynamic driving force and its application for analyzing the endogenous CO2 fixation potential of … O Hädicke, A von Kamp, T Aydogan, S Klamt PLoS computational biology 14 (9), e1006492, 2018 | 57 | 2018 |
Enforced ATP futile cycling increases specific productivity and yield of anaerobic lactate production in Escherichia coli O Hädicke, K Bettenbrock, S Klamt Biotechnology and bioengineering 112 (10), 2195-2199, 2015 | 57 | 2015 |
Stoichiometric and constraint-based analysis of biochemical reaction networks S Klamt, O Hädicke, A von Kamp Large-scale networks in engineering and life sciences, 263-316, 2014 | 35 | 2014 |
The avian cell line AGE1. CR. pIX characterized by metabolic flux analysis V Lohr, O Hädicke, Y Genzel, I Jordan, H Büntemeyer, S Klamt, U Reichl BMC biotechnology 14, 1-14, 2014 | 28 | 2014 |
Manipulation of the ATP pool as a tool for metabolic engineering O Hädicke, S Klamt Biochemical Society Transactions 43 (6), 1140-1145, 2015 | 25 | 2015 |
CASOP GS: Computing intervention strategies targeted at production improvement in genome-scale metabolic networks K Bohl, LF Figueiredo, O Hädicke, S Klamt, C Kost, S Schuster, C Kaleta Gesellschaft für Informatik eV, 2010 | 24 | 2010 |
Stepwise reduction of the culture redox potential allows the analysis of microaerobic metabolism and photosynthetic membrane synthesis in Rhodospirillum rubrum L Carius, O Hädicke, H Grammel Biotechnology and bioengineering 110 (2), 573-585, 2013 | 19 | 2013 |
New light on ancient enzymes – in vitro CO2 Fixation by Pyruvate Synthase of Desulfovibrio africanus and Sulfolobus acidocaldarius A Witt, R Pozzi, S Diesch, O Hädicke, H Grammel The FEBS Journal 286 (22), 4494-4508, 2019 | 12 | 2019 |
Evaluating differences of metabolic performances: Statistical methods and their application to animal cell cultivations O Hädicke, V Lohr, Y Genzel, U Reichl, S Klamt Biotechnology and bioengineering 110 (10), 2633-2642, 2013 | 11 | 2013 |
Large-scale networks in engineering and life sciences S Klamt, O Hädicke, A Von Kamp, P Benner, R Findeisen, D Flockerzi, ... Benner, P., Findeisen, R., Flockerzi, D., Reichl, U., Sundmacher, K., Eds …, 2014 | 7 | 2014 |
Modellbasierte Identifizierung von Interventionsstrategien für Stoffwechselnetzwerke O Hädicke Shaker Verlag Aachen, 2014 | 2 | 2014 |
Corrigendum: EColiCore2: a reference network model of the central metabolism of Escherichia coliand relationships to its genome-scale parent model O Hädicke, S Klamt | | 2017 |
Corrigendum: EColiCore2: a reference network model of the central metabolism of Escherichia coli and relationships to its genome-scale parent model O Hädicke, S Klamt Scientific Reports 7, 2017 | | 2017 |