Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance H Huang, R Chopra, GL Verdine, SC Harrison Science 282 (5394), 1669-1675, 1998 | 1851 | 1998 |
Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix LD Walensky, AL Kung, I Escher, TJ Malia, S Barbuto, RD Wright, ... science 305 (5689), 1466-1470, 2004 | 1705 | 2004 |
An all-hydrocarbon cross-linking system for enhancing the helicity and metabolic stability of peptides CE Schafmeister, J Po, GL Verdine Journal of the American Chemical Society 122 (24), 5891-5892, 2000 | 1268 | 2000 |
Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA SD Bruner, DPG Norman, GL Verdine nature 403 (6772), 859-866, 2000 | 1187 | 2000 |
The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun J Jain, PG McCafffrey, Z Miner, TK Kerppola, JN Lambert, GL Verdine, ... Nature 365 (6444), 352-355, 1993 | 969 | 1993 |
Direct inhibition of the NOTCH transcription factor complex RE Moellering, M Cornejo, TN Davis, CD Bianco, JC Aster, SC Blacklow, ... Nature 462 (7270), 182-188, 2009 | 938 | 2009 |
Regulation of MLL1 H3K4 methyltransferase activity by its core components Y Dou, TA Milne, AJ Ruthenburg, S Lee, JW Lee, GL Verdine, CD Allis, ... Nature structural & molecular biology 13 (8), 713-719, 2006 | 894 | 2006 |
Structure of the NF-κB p50 homodimer bound to DNA CW Müller, FA Rey, M Sodeoka, GL Verdine, SC Harrison Nature 373 (6512), 311-317, 1995 | 779 | 1995 |
Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide F Bernal, AF Tyler, SJ Korsmeyer, LD Walensky, GL Verdine Journal of the American Chemical Society 129 (9), 2456-2457, 2007 | 694 | 2007 |
Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA M Tomasz, R Lipman, D Chowdary, J Pawlak, GL Verdine, K Nakanishi Science 235 (4793), 1204-1208, 1987 | 679 | 1987 |
A base-excision DNA-repair protein finds intrahelical lesion bases by fast sliding in contact with DNA PC Blainey, AM van Oijen, A Banerjee, GL Verdine, XS Xie Proceedings of the National Academy of Sciences 103 (15), 5752-5757, 2006 | 590 | 2006 |
Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily HM Nash, SD Bruner, OD Schärer, T Kawate, TA Addona, E Spooner, ... Current Biology 6 (8), 968-980, 1996 | 588 | 1996 |
Stapled peptides for intracellular drug targets GL Verdine, GJ Hilinski Methods in enzymology 503, 3-33, 2012 | 538 | 2012 |
DNA (cytosine-5)-methyltransferases in mouse cells and tissues. Studies with a mechanism-based probe JA Yoder, NS Soman, GL Verdine, TH Bestor Journal of molecular biology 270 (3), 385-395, 1997 | 516 | 1997 |
A stapled BID BH3 helix directly binds and activates BAX LD Walensky, K Pitter, J Morash, KJ Oh, S Barbuto, J Fisher, E Smith, ... Molecular cell 24 (2), 199-210, 2006 | 505 | 2006 |
Isolation of the cyclosporin-sensitive T cell transcription factor NFATp PG McCaffrey, C Luo, TK Kerppola, J Jain, TM Badalian, AM Ho, ... Science 262 (5134), 750-754, 1993 | 501 | 1993 |
The crystal structure of Haelll methyltransferase covalently complexed to DNA: An extrahelical cytosine and rearranged base pairing KM Reinisch, L Chen, GL Verdine, WN Lipscomb Cell 82 (1), 143-153, 1995 | 495 | 1995 |
The challenge of drugging undruggable targets in cancer: lessons learned from targeting BCL-2 family members GL Verdine, LD Walensky Clinical cancer research 13 (24), 7264-7270, 2007 | 485 | 2007 |
Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis YW Kim, TN Grossmann, GL Verdine Nature protocols 6 (6), 761-771, 2011 | 451 | 2011 |
Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA A Banerjee, W Yang, M Karplus, GL Verdine nature 434 (7033), 612-618, 2005 | 424 | 2005 |