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Simon Koplev
Simon Koplev
PhD candidate at University of Cambridge
Dirección de correo verificada de cruk.cam.ac.uk
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Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
MV Kuleshov, MR Jones, AD Rouillard, NF Fernandez, Q Duan, Z Wang, ...
Nucleic acids research 44 (W1), W90-W97, 2016
56232016
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
R Malik, G Chauhan, M Traylor, M Sargurupremraj, Y Okada, A Mishra, ...
Nature genetics 50 (4), 524-537, 2018
8272018
The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations
AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ...
Cell systems 6 (1), 13-24, 2018
3132018
Macrophage Trafficking, Inflammatory Resolution, and Genomics in Atherosclerosis: JACC Macrophage in CVD Series (Part 2)
KJ Moore, S Koplev, EA Fisher, I Tabas, JLM Björkegren, AC Doran, ...
Journal of the American College of Cardiology 72 (18), 2181-2197, 2018
1172018
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes
N Franceschini, C Giambartolomei, PS De Vries, C Finan, JC Bis, ...
Nature communications 9 (1), 1-14, 2018
1032018
Unraveling tumor–immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy
A Jiménez-Sánchez, P Cybulska, KLV Mager, S Koplev, O Cast, ...
Nature genetics 52 (6), 582-593, 2020
1002020
Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade
Y Wang, V Nanda, D Direnzo, J Ye, S Xiao, Y Kojima, KL Howe, KU Jarr, ...
Proceedings of the National Academy of Sciences 117 (27), 15818-15826, 2020
552020
A strategy for discovery of endocrine interactions with application to whole-body metabolism
MM Seldin, S Koplev, P Rajbhandari, L Vergnes, GM Rosenberg, Y Meng, ...
Cell metabolism 27 (5), 1138-1155. e6, 2018
422018
Contribution of gene regulatory networks to heritability of coronary artery disease
L Zeng, HA Talukdar, S Koplev, C Giannarelli, T Ivert, LM Gan, ...
Journal of the American College of Cardiology 73 (23), 2946-2957, 2019
402019
JCAD, a Gene at the 10p11 Coronary Artery Disease Locus, Regulates Hippo Signaling in Endothelial Cells
PD Jones, MA Kaiser, M Ghaderi Najafabadi, S Koplev, Y Zhao, ...
Arteriosclerosis, thrombosis, and vascular biology 38 (8), 1711-1722, 2018
372018
Sex-stratified gene regulatory networks reveal female key driver genes of atherosclerosis involved in smooth muscle cell phenotype switching
RJG Hartman, K Owsiany, L Ma, S Koplev, K Hao, L Slenders, M Civelek, ...
Circulation 143 (7), 713-726, 2021
342021
Integration of pan-cancer transcriptomics with RPPA proteomics reveals mechanisms of epithelial-mesenchymal transition
S Koplev, K Lin, AB Dohlman, A Ma’ayan
PLoS computational biology 14 (1), e1005911, 2018
322018
Developing a framework for digital objects in the Big Data to Knowledge (BD2K) commons: Report from the Commons Framework Pilots workshop
KM Jagodnik, S Koplev, SL Jenkins, L Ohno-Machado, B Paten, ...
Journal of biomedical informatics 71, 49-57, 2017
282017
CD90 identifies adventitial mesenchymal progenitor cells in adult human medium-and large-sized arteries
KC Michelis, A Nomura-Kitabayashi, L Lecce, O Franzén, S Koplev, Y Xu, ...
Stem Cell Reports 11 (1), 242-257, 2018
252018
MicroRNA-210, MicroRNA-331, and MicroRNA-7 Are Differentially Regulated in Treated HIV-1–Infected Individuals and Are Associated With Markers of Systemic Inflammation
V Ballegaard, U Ralfkiaer, KK Pedersen, M Hove, S Koplev, P Brændstrup, ...
JAIDS Journal of Acquired Immune Deficiency Syndromes 74 (4), e104-e113, 2017
252017
Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus
V Nanda, T Wang, M Pjanic, B Liu, T Nguyen, LP Matic, U Hedin, ...
PLoS genetics 14 (11), e1007755, 2018
242018
An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease
AT Cohain, WT Barrington, DM Jordan, ND Beckmann, CA Argmann, ...
Nature communications 12 (1), 1-13, 2021
232021
Functional and transcriptomic insights into pathogenesis of R9C phospholamban mutation using human induced pluripotent stem cell-derived cardiomyocytes
DK Ceholski, IC Turnbull, CW Kong, S Koplev, J Mayourian, PA Gorski, ...
Journal of molecular and cellular cardiology 119, 147-154, 2018
222018
Dynamic rearrangement of cell states detected by systematic screening of sequential anticancer treatments
S Koplev, J Longden, J Ferkinghoff-Borg, MB Bjerregård, TR Cox, JT Erler, ...
Cell Reports 20 (12), 2784-2791, 2017
202017
A mechanistic framework for cardiometabolic and coronary artery diseases
S Koplev, M Seldin, K Sukhavasi, R Ermel, S Pang, L Zeng, S Bankier, ...
Nature Cardiovascular Research 1 (1), 85-100, 2022
122022
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Artículos 1–20