Deniz Dalkara
Deniz Dalkara
1 INSERM, U968, Paris, F-75012, France; 2 Sorbonne Universités, UPMC Univ Paris 06, UMR_S 968
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In vivo–directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous
D Dalkara, LC Byrne, RR Klimczak, M Visel, L Yin, WH Merigan, ...
Science translational medicine 5 (189), 189ra76-189ra76, 2013
Partial recovery of visual function in a blind patient after optogenetic therapy
JA Sahel, E Boulanger-Scemama, C Pagot, A Arleo, F Galluppi, JN Martel, ...
Nature medicine 27 (7), 1223-1229, 2021
Rod-derived cone viability factor promotes cone survival by stimulating aerobic glycolysis
N Aït-Ali, R Fridlich, G Millet-Puel, E Clérin, F Delalande, C Jaillard, ...
Cell 161 (4), 817-832, 2015
Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous
D Dalkara, KD Kolstad, N Caporale, M Visel, RR Klimczak, DV Schaffer, ...
Molecular Therapy 17 (12), 2096-2102, 2009
A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells
RR Klimczak, JT Koerber, D Dalkara, JG Flannery, DV Schaffer
PloS one 4 (10), e7467, 2009
Emerging therapies for inherited retinal degeneration
HPN Scholl, RW Strauss, MS Singh, D Dalkara, B Roska, S Picaud, ...
Science translational medicine 8 (368), 368rv6-368rv6, 2016
Molecular evolution of adeno-associated virus for enhanced glial gene delivery
JT Koerber, R Klimczak, JH Jang, D Dalkara, JG Flannery, DV Schaffer
Molecular Therapy 17 (12), 2088-2095, 2009
Intravitreal injection of AAV2 transduces macaque inner retina
L Yin, K Greenberg, JJ Hunter, D Dalkara, KD Kolstad, BD Masella, ...
Investigative ophthalmology & visual science 52 (5), 2775-2783, 2011
Targeting channelrhodopsin-2 to ON-bipolar cells with vitreally administered AAV restores ON and OFF visual responses in blind mice
E Macé, R Caplette, O Marre, A Sengupta, A Chaffiol, P Barbe, ...
Molecular Therapy 23 (1), 7-16, 2015
LiGluR restores visual responses in rodent models of inherited blindness
N Caporale, KD Kolstad, T Lee, I Tochitsky, D Dalkara, D Trauner, ...
Molecular therapy 19 (7), 1212-1219, 2011
Rapid optical control of nociception with an ion-channel photoswitch
A Mourot, T Fehrentz, Y Le Feuvre, CM Smith, C Herold, D Dalkara, ...
Nature methods 9 (4), 396-402, 2012
Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration
LC Byrne, D Dalkara, G Luna, SK Fisher, E Clérin, JA Sahel, T Léveillard, ...
The Journal of clinical investigation 125 (1), 105-116, 2015
Red‐shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina
A Sengupta, A Chaffiol, E Macé, R Caplette, M Desrosiers, M Lampič, ...
EMBO molecular medicine 8 (11), 1248-1264, 2016
Let there be light: gene and cell therapy for blindness
D Dalkara, O Goureau, K Marazova, JA Sahel
Human gene therapy 27 (2), 134-147, 2016
A new promoter allows optogenetic vision restoration with enhanced sensitivity in macaque retina
A Chaffiol, R Caplette, C Jaillard, E Brazhnikova, M Desrosiers, E Dubus, ...
Molecular Therapy 25 (11), 2546-2560, 2017
Long-distance axonal regeneration induced by CNTF gene transfer is impaired by axonal misguidance in the injured adult optic nerve
V Pernet, S Joly, D Dalkara, N Jordi, O Schwarz, F Christ, DV Schaffer, ...
Neurobiology of disease 51, 202-213, 2013
Misguidance and modulation of axonal regeneration by Stat3 and Rho/ROCK signaling in the transparent optic nerve
V Pernet, S Joly, N Jordi, D Dalkara, A Guzik-Kornacka, JG Flannery, ...
Cell death & disease 4 (7), e734-e734, 2013
AAV mediated GDNF secretion from retinal glia slows down retinal degeneration in a rat model of retinitis pigmentosa
D Dalkara, KD Kolstad, KI Guerin, NV Hoffmann, M Visel, RR Klimczak, ...
Molecular Therapy 19 (9), 1602-1608, 2011
Noninvasive gene delivery to foveal cones for vision restoration
H Khabou, M Garita-Hernandez, A Chaffiol, S Reichman, C Jaillard, ...
JCI insight 3 (2), 2018
Vertebrate cone opsins enable sustained and highly sensitive rapid control of Gi/o signaling in anxiety circuitry
OA Masseck, K Spoida, D Dalkara, T Maejima, JM Rubelowski, ...
Neuron 81 (6), 1263-1273, 2014
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20