A genome‐scale metabolic reconstruction for Escherichia coli K‐12 MG1655 that accounts for 1260 ORFs and thermodynamic information AM Feist, CS Henry, JL Reed, M Krummenacker, AR Joyce, PD Karp, ... Molecular systems biology 3 (1), 121, 2007 | 1759 | 2007 |
Thermodynamics-based metabolic flux analysis CS Henry, LJ Broadbelt, V Hatzimanikatis Biophysical journal 92 (5), 1792-1805, 2007 | 765 | 2007 |
Group contribution method for thermodynamic analysis of complex metabolic networks MD Jankowski, CS Henry, LJ Broadbelt, V Hatzimanikatis Biophysical journal 95 (3), 1487-1499, 2008 | 500 | 2008 |
Exploring the diversity of complex metabolic networks V Hatzimanikatis, C Li, JA Ionita, CS Henry, MD Jankowski, LJ Broadbelt Bioinformatics 21 (8), 1603-1609, 2005 | 439 | 2005 |
MEMOTE for standardized genome-scale metabolic model testing C Lieven, ME Beber, BG Olivier, FT Bergmann, M Ataman, P Babaei, ... Nature biotechnology 38 (3), 272-276, 2020 | 403 | 2020 |
Kinetic models in industrial biotechnology–improving cell factory performance J Almquist, M Cvijovic, V Hatzimanikatis, J Nielsen, M Jirstrand Metabolic engineering 24, 38-60, 2014 | 345 | 2014 |
Metabolic flux analysis of hybridoma cells in different culture media using mass balances HPJ Bonarius, V Hatzimanikatis, KPH Meesters, CD De Gooijer, ... Biotechnology and Bioengineering 50 (3), 299-318, 1996 | 334 | 1996 |
Metabolic fluxes in riboflavin-producing Bacillus subtilis U Sauer, V Hatzimanikatis, JE Bailey, M Hochuli, T Szyperski, K Wüthrich Nature biotechnology 15 (5), 448-452, 1997 | 328 | 1997 |
Genome-scale thermodynamic analysis of Escherichia coli metabolism CS Henry, MD Jankowski, LJ Broadbelt, V Hatzimanikatis Biophysical journal 90 (4), 1453-1461, 2006 | 286 | 2006 |
Inverse metabolic engineering: a strategy for directed genetic engineering of useful phenotypes JE Bailey, A Sburlati, V Hatzimanikatis, K Lee, WA Renner, PS Tsai Biotechnology and Bioengineering 52 (1), 109-121, 1996 | 261 | 1996 |
Physiology and metabolic fluxes of wild-type and riboflavin-producing Bacillus subtilis U Sauer, V Hatzimanikatis, HP Hohmann, M Manneberg, AP Van Loon, ... Applied and environmental microbiology 62 (10), 3687-3696, 1996 | 237 | 1996 |
Production of lactate using crabtree negative organisms in varying culture conditions V Rajgarhia, V Hatzimanikatis, S Olson, T Carlson, JN Starr, JJ Kolstad, ... US Patent 6,485,947, 2002 | 208 | 2002 |
Discovery and analysis of novel metabolic pathways for the biosynthesis of industrial chemicals: 3‐hydroxypropanoate CS Henry, LJ Broadbelt, V Hatzimanikatis Biotechnology and bioengineering 106 (3), 462-473, 2010 | 197 | 2010 |
Metabolic control analysis under uncertainty: framework development and case studies L Wang, I Birol, V Hatzimanikatis Biophysical journal 87 (6), 3750-3763, 2004 | 184 | 2004 |
Analysis and design of metabolic reaction networks via mixed‐integer linear optimization V Hatzimanikatis, CA Floudas, JE Bailey AIChE Journal 42 (5), 1277-1292, 1996 | 178 | 1996 |
Towards kinetic modeling of genome‐scale metabolic networks without sacrificing stoichiometric, thermodynamic and physiological constraints A Chakrabarti, L Miskovic, KC Soh, V Hatzimanikatis Biotechnology journal 8 (9), 1043-1057, 2013 | 177 | 2013 |
ATLAS of biochemistry: a repository of all possible biochemical reactions for synthetic biology and metabolic engineering studies N Hadadi, J Hafner, A Shajkofci, A Zisaki, V Hatzimanikatis ACS synthetic biology 5 (10), 1155-1166, 2016 | 175 | 2016 |
Dynamical analysis of gene networks requires both mRNA and protein expression information V Hatzimanikatis, KH Lee Metabolic engineering 1 (4), 275-281, 1999 | 158 | 1999 |
Antihypertensive drugs metabolism: an update to pharmacokinetic profiles and computational approaches A Zisaki, L Miskovic, V Hatzimanikatis Current pharmaceutical design 21 (6), 806-822, 2015 | 152 | 2015 |
Insights into the relation between mRNA and protein expression patterns: I. Theoretical considerations A Mehra, KH Lee, V Hatzimanikatis Biotechnology and bioengineering 84 (7), 822-833, 2003 | 149 | 2003 |