| NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells: implication of NBS1 in alternative lengthening of … G Wu, WH Lee, PL Chen Journal of Biological Chemistry 275 (39), 30618-30622, 2000 | 299 | 2000 |
| Assembly of functional ALT-associated promyelocytic leukemia bodies requires Nijmegen breakage syndrome G Wu, X Jiang, WH Lee, PL Chen Cancer research 63 (10), 2589-2595, 2003 | 182 | 2003 |
| 14-3-3 adaptor proteins recruit AID to 5′-AGCT-3′–rich switch regions for class switch recombination Z Xu, Z Fulop, G Wu, EJ Pone, J Zhang, T Mai, LM Thomas, A Al-Qahtani, ... Nature structural & molecular biology 17 (9), 1124-1135, 2010 | 167 | 2010 |
| Functional TCR T cell screening using single-cell droplet microfluidics AI Segaliny, G Li, L Kong, C Ren, X Chen, JK Wang, D Baltimore, G Wu, ... Lab on a Chip 18 (24), 3733-3749, 2018 | 157 | 2018 |
| Small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal G Wu, XL Qiu, L Zhou, J Zhu, R Chamberlin, J Lau, PL Chen, WH Lee Cancer research 68 (20), 8393-8399, 2008 | 128 | 2008 |
| A novel role of the chromokinesin Kif4A in DNA damage response G Wu, L Zhou, L Khidr, XE Guo, W Kim, YM Lee, T Krasieva, PL Chen Cell Cycle 7 (13), 2013-2020, 2008 | 100 | 2008 |
| A novel small molecule RAD51 inactivator overcomes imatinib‐resistance in chronic myeloid leukaemia J Zhu, L Zhou, G Wu, H Konig, X Lin, G Li, XL Qiu, CF Chen, CM Hu, ... EMBO molecular medicine 5 (3), 353-365, 2013 | 94 | 2013 |
| Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control LWH Lin YT, Chen Y, Wu G Oncogene 25 (52), 6901-6914, 2006 | 83 | 2006 |
| Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint R Wei, B Ngo, G Wu, WH Lee Molecular biology of the cell 22 (19), 3584-3594, 2011 | 82 | 2011 |
| Synthesis and biological evaluation of a series of novel inhibitor of Nek2/Hec1 analogues XL Qiu, G Li, G Wu, J Zhu, L Zhou, PL Chen, AR Chamberlin, WH Lee Journal of medicinal chemistry 52 (6), 1757-1767, 2009 | 80 | 2009 |
| Hice1, a novel microtubule-associated protein required for maintenance of spindle integrity and chromosomal stability in human cells G Wu, YT Lin, R Wei, Y Chen, Z Shan, WH Lee Molecular and cellular biology 28 (11), 3652-3662, 2008 | 72 | 2008 |
| Role of SUV3 helicase in maintaining mitochondrial homeostasis in human cells L Khidr, G Wu, A Davila, V Procaccio, D Wallace, WH Lee Journal of Biological Chemistry 283 (40), 27064-27073, 2008 | 63 | 2008 |
| Novel small molecules disrupting Hec1/Nek2 interaction ablate tumor progression by triggering Nek2 degradation through a death-trap mechanism CM Hu, J Zhu, XE Guo, W Chen, XL Qiu, B Ngo, R Chien, YV Wang, ... Oncogene 34 (10), 1220-1230, 2015 | 53 | 2015 |
| Aurora-A phosphorylates Augmin complex component Hice1 protein at an N-terminal serine/threonine cluster to modulate its microtubule binding activity during spindle assembly CY Tsai, B Ngo, A Tapadia, PH Hsu, G Wu, WH Lee Journal of Biological Chemistry 286 (34), 30097-30106, 2011 | 44 | 2011 |
| RINT-1 serves as a tumor suppressor and maintains Golgi dynamics and centrosome integrity for cell survival X Lin, CC Liu, Q Gao, X Zhang, GK Wu, WH Lee Molecular and cellular biology 27 (13), 4905-4916, 2007 | 44 | 2007 |
| Structural requirements of chromokinesin Kif4A for its proper function in mitosis G Wu, PL Chen Biochemical and biophysical research communications 372 (3), 454-458, 2008 | 38 | 2008 |
| Detection of prawn white spot baculovirus by polymerase chain reaction W WANG, J HE, F YANG, G Wu, X Xu Acta oceanologica sinica 18 (4), 591-598, 1999 | 38 | 1999 |
| Nanoimaging of focal adhesion dynamics in 3D CL Chiu, JS Aguilar, CY Tsai, GK Wu, E Gratton, MA Digman PLoS One 9 (6), e99896, 2014 | 37 | 2014 |
| CtIP, a multivalent adaptor connecting transcriptional regulation, checkpoint control and tumor suppression G Wu, WH Lee Cell Cycle 5 (15), 1592-1596, 2006 | 34 | 2006 |
| Stereoselective synthesis of chiral IBR2 analogues XL Qiu, J Zhu, G Wu, WH Lee, AR Chamberlin The Journal of Organic Chemistry 74 (5), 2018-2027, 2009 | 31 | 2009 |
