| A SARS-CoV-2 protein interaction map reveals targets for drug repurposing DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ... Nature 583 (7816), 459-468, 2020 | 3686 | 2020 |
| VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche RN Kaplan, RD Riba, S Zacharoulis, AH Bramley, L Vincent, C Costa, ... Nature 438 (7069), 820-827, 2005 | 3542 | 2005 |
| The translational landscape of mTOR signalling steers cancer initiation and metastasis AC Hsieh, Y Liu, MP Edlind, NT Ingolia, MR Janes, A Sher, EY Shi, ... Nature 485 (7396), 55-61, 2012 | 1310 | 2012 |
| Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2 ME Feldman, B Apsel, A Uotila, R Loewith, ZA Knight, D Ruggero, ... PLoS biology 7 (2), e1000038, 2009 | 1292 | 2009 |
| Does the ribosome translate cancer? D Ruggero, PP Pandolfi Nature Reviews Cancer 3 (3), 179-192, 2003 | 1118 | 2003 |
| PML is essential for multiple apoptotic pathways ZG Wang, D Ruggero, S Ronchetti, S Zhong, M Gaboli, R Rivi, ... Nature genetics 20 (3), 266-272, 1998 | 737 | 1998 |
| The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis D Ruggero, L Montanaro, L Ma, W Xu, P Londei, C Cordon-Cardo, ... Nature medicine 10 (5), 484-486, 2004 | 687 | 2004 |
| IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2 JP Upton, L Wang, D Han, ES Wang, NE Huskey, L Lim, M Truitt, ... Science 338 (6108), 818-822, 2012 | 636 | 2012 |
| Autism-related deficits via dysregulated eIF4E-dependent translational control CG Gkogkas, A Khoutorsky, I Ran, E Rampakakis, T Nevarko, ... Nature 493 (7432), 371-377, 2013 | 519 | 2013 |
| Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E AC Hsieh, M Costa, O Zollo, C Davis, ME Feldman, JR Testa, O Meyuhas, ... Cancer cell 17 (3), 249-261, 2010 | 499 | 2010 |
| Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification D Ruggero, S Grisendi, F Piazza, E Rego, F Mari, PH Rao, ... Science 299 (5604), 259-262, 2003 | 480 | 2003 |
| Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency M Barna, A Pusic, O Zollo, M Costa, N Kondrashov, E Rego, PH Rao, ... Nature 456 (7224), 971-975, 2008 | 437 | 2008 |
| Impaired control of IRES-mediated translation in X-linked dyskeratosis congenita A Yoon, G Peng, Y Brandenburg, O Zollo, W Xu, E Rego, D Ruggero Science 312 (5775), 902-906, 2006 | 421 | 2006 |
| ER stress–mediated autophagy promotes Myc-dependent transformation and tumor growth LS Hart, JT Cunningham, T Datta, S Dey, F Tameire, SL Lehman, BO Qiu, ... The Journal of clinical investigation 122 (12), 4621-4634, 2012 | 383 | 2012 |
| Exaggerated translation causes synaptic and behavioural aberrations associated with autism E Santini, TN Huynh, AF MacAskill, AG Carter, P Pierre, D Ruggero, ... Nature 493 (7432), 411-415, 2013 | 350 | 2013 |
| Targeting the eIF4F translation initiation complex: a critical nexus for cancer development J Pelletier, J Graff, D Ruggero, N Sonenberg Cancer research 75 (2), 250-263, 2015 | 325 | 2015 |
| New frontiers in translational control of the cancer genome ML Truitt, D Ruggero Nature Reviews Cancer 16 (5), 288-304, 2016 | 323 | 2016 |
| Translational control in cancer etiology D Ruggero Cold Spring Harbor perspectives in biology 5 (2), a012336, 2013 | 316 | 2013 |
| Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis S Zhong, P Salomoni, S Ronchetti, A Guo, D Ruggero, PP Pandolfi The Journal of experimental medicine 191 (4), 631-640, 2000 | 311 | 2000 |
| Differential requirements for eIF4E dose in normal development and cancer ML Truitt, CS Conn, Z Shi, X Pang, T Tokuyasu, AM Coady, Y Seo, ... Cell 162 (1), 59-71, 2015 | 308 | 2015 |
