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Quadram Institute Bioscience
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SignaLink 2–a signaling pathway resource with multi-layered regulatory networks
D Fazekas, M Koltai, D Türei, D Módos, M Pálfy, Z Dúl, L Zsákai, ...
BMC systems biology 7 (1), 1-15, 2013
1902013
The NRF2-related interactome and regulome contain multifunctional proteins and fine-tuned autoregulatory loops
D Papp, K Lenti, D Módos, D Fazekas, Z Dúl, D Türei, L Földvári-Nagy, ...
FEBS letters 586 (13), 1795-1802, 2012
1192012
Developments in toxicogenomics: understanding and predicting compound-induced toxicity from gene expression data
B Alexander-Dann, LL Pruteanu, E Oerton, N Sharma, I Berindan-Neagoe, ...
Molecular omics 14 (4), 218-236, 2018
782018
Autophagy Regulatory Network—A systems-level bioinformatics resource for studying the mechanism and regulation of autophagy
D Türei, L Földvári-Nagy, D Fazekas, D Módos, J Kubisch, T Kadlecsik, ...
Autophagy 11 (1), 155-165, 2015
772015
SARS-CoV-2 causes a different cytokine response compared to other cytokine storm-causing respiratory viruses in severely ill patients
M Olbei, I Hautefort, D Modos, A Treveil, M Poletti, L Gul, ...
Frontiers in immunology 12, 629193, 2021
762021
Cancer stem cells display extremely large evolvability: alternating plastic and rigid networks as a potential mechanism: network models, novel therapeutic target strategies …
P Csermely, J Hódsági, T Korcsmáros, D Módos, ÁR Perez-Lopez, ...
Seminars in cancer biology 30, 42-51, 2015
742015
Integrated intra‐and intercellular signaling knowledge for multicellular omics analysis
D Türei, A Valdeolivas, L Gul, N Palacio‐Escat, M Klein, O Ivanova, ...
Molecular systems biology 17 (3), e9923, 2021
722021
NRF2-ome: an integrated web resource to discover protein interaction and regulatory networks of NRF2
D Türei, D Papp, D Fazekas, L Földvári-Nagy, D Módos, K Lenti, ...
Oxidative medicine and cellular longevity 2013, 2013
442013
COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms
M Ostaszewski, A Niarakis, A Mazein, I Kuperstein, R Phair, ...
Molecular systems biology 17 (10), e10387, 2021
312021
Adaptation and learning of molecular networks as a description of cancer development at the systems-level: Potential use in anti-cancer therapies
DM Gyurkó, DV Veres, D Módos, K Lenti, T Korcsmáros, P Csermely
Seminars in Cancer Biology 23 (4), 262-269, 2013
302013
Neighbours of cancer-related proteins have key influence on pathogenesis and could increase the drug target space for anticancer therapies
D Módos, KC Bulusu, D Fazekas, J Kubisch, J Brooks, I Marczell, ...
NPJ systems biology and applications 3 (1), 1-13, 2017
262017
Targets of drugs are generally and targets of drugs having side effects are specifically good spreaders of human interactome perturbations
ÁR Perez-Lopez, KZ Szalay, D Türei, D Módos, K Lenti, T Korcsmáros, ...
Scientific reports 5 (1), 1-9, 2015
252015
Extracellular vesicles produced by the human commensal gut bacterium Bacteroides thetaiotaomicron affect host immune pathways in a cell‐type specific manner …
L Gul, D Modos, S Fonseca, M Madgwick, JP Thomas, P Sudhakar, ...
Journal of Extracellular Vesicles 11 (1), e12189, 2022
122022
ViralLink: An integrated workflow to investigate the effect of SARS-CoV-2 on intracellular signalling and regulatory pathways
A Treveil, B Bohar, P Sudhakar, L Gul, L Csabai, M Olbei, M Poletti, ...
PLoS computational biology 17 (2), e1008685, 2021
92021
Transcriptomics predicts compound synergy in drug and natural product treated glioblastoma cells
LL Pruteanu, L Kopanitsa, D Módos, E Kletnieks, E Samarova, A Bender, ...
Plos one 15 (9), e0239551, 2020
92020
The emerging role of bile acids in the pathogenesis of inflammatory bowel disease
JP Thomas, D Modos, SM Rushbrook, N Powell, T Korcsmaros
Frontiers in Immunology, 246, 2022
82022
Identification of critical paralog groups with indispensable roles in the regulation of signaling flow
KL Dezso Modos, Johanne Brooks, David Fazekas, Eszter Ari, Tibor Vellai ...
Scientific Reports 6, 2016
82016
ADDI: Recommending alternatives for drug–drug interactions with negative health effects
M Allahgholi, H Rahmani, D Javdani, G Weiss, D Módos
Computers in Biology and Medicine 125, 103969, 2020
62020
SignaLink3: a multi-layered resource to uncover tissue-specific signaling networks
L Csabai, D Fazekas, T Kadlecsik, M Szalay-Bekő, B Bohár, M Madgwick, ...
Nucleic acids research 50 (D1), D701-D709, 2022
52022
Understanding Conditional Associations between ToxCast in Vitro Readouts and the Hepatotoxicity of Compounds Using Rule-Based Methods
SY Mahmoud, F Svensson, A Zoufir, D Módos, AM Afzal, A Bender
Chemical Research in Toxicology 33 (1), 137-153, 2019
42019
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Artículos 1–20