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Shilpa S Dhar, Ph.D.
Shilpa S Dhar, Ph.D.
Dirección de correo verificada de mdanderson.org
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UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells
JH Kim, A Sharma, SS Dhar, SH Lee, B Gu, CH Chan, HK Lin, MG Lee
Cancer research 74 (6), 1705-1717, 2014
2432014
Trans-tail regulation of MLL4-catalyzed H3K4 methylation by H4R3 symmetric dimethylation is mediated by a tandem PHD of MLL4
SS Dhar, SH Lee, PY Kan, P Voigt, L Ma, X Shi, D Reinberg, MG Lee
Genes & development 26 (24), 2749-2762, 2012
1992012
KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling
KW Wagner, H Alam, SS Dhar, U Giri, N Li, Y Wei, D Giri, T Cascone, ...
The Journal of clinical investigation 123 (12), 5231-5246, 2013
1872013
Nuclear respiratory factor 1 regulates all ten nuclear-encoded subunits of cytochrome c oxidase in neurons
SS Dhar, S Ongwijitwat, MTT Wong-Riley
Journal of Biological Chemistry 283 (6), 3120-3129, 2008
1842008
KMT2D deficiency impairs super-enhancers to confer a glycolytic vulnerability in lung cancer
H Alam, M Tang, M Maitituoheti, SS Dhar, M Kumar, CY Han, CR Ambati, ...
Cancer cell 37 (4), 599-617. e7, 2020
1522020
MLL4 is required to maintain broad H3K4me3 peaks and super-enhancers at tumor suppressor genes
SS Dhar, D Zhao, T Lin, B Gu, K Pal, SJ Wu, H Alam, J Lv, K Yun, ...
Molecular cell 70 (5), 825-841. e6, 2018
1272018
ZMYND8 reads the dual histone mark H3K4me1-H3K14ac to antagonize the expression of metastasis-linked genes
NA Li, Y Li, J Lv, X Zheng, H Wen, H Shen, G Zhu, TY Chen, SS Dhar, ...
Molecular cell 63 (3), 470-484, 2016
1242016
JARID1D is a suppressor and prognostic marker of prostate cancer invasion and metastasis
N Li, SS Dhar, TY Chen, PY Kan, Y Wei, JH Kim, CH Chan, HK Lin, ...
Cancer research 76 (4), 831-843, 2016
1102016
Coupling of energy metabolism and synaptic transmission at the transcriptional level: role of nuclear respiratory factor 1 in regulating both cytochrome c oxidase and NMDA …
SS Dhar, MTT Wong-Riley
Journal of Neuroscience 29 (2), 483-492, 2009
1012009
An essential role for UTX in resolution and activation of bivalent promoters
SS Dhar, SH Lee, K Chen, G Zhu, WK Oh, K Allton, O Gafni, YZ Kim, ...
Nucleic acids research 44 (8), 3659-3674, 2016
752016
A feedback loop comprising PRMT7 and miR-24-2 interplays with Oct4, Nanog, Klf4 and c-Myc to regulate stemness
SH Lee, TY Chen, SS Dhar, B Gu, K Chen, YZ Kim, W Li, MG Lee
Nucleic acids research 44 (22), 10603-10618, 2016
742016
HP1γ promotes lung adenocarcinoma by downregulating the transcription-repressive regulators NCOR2 and ZBTB7A
H Alam, N Li, SS Dhar, SJ Wu, J Lv, K Chen, ER Flores, L Baseler, ...
Cancer research 78 (14), 3834-3848, 2018
722018
Transcriptional repression of histone deacetylase 3 by the histone demethylase KDM2A is coupled to tumorigenicity of lung cancer cells
SS Dhar, H Alam, N Li, KW Wagner, J Chung, YW Ahn, MG Lee
Journal of Biological Chemistry 289 (11), 7483-7496, 2014
722014
Chemotherapy-induced late transgenerational effects in mice
LL Kujjo, EA Chang, RJG Pereira, S Dhar, B Marrero-Rosado, ...
PloS one 6 (3), e17877, 2011
572011
Nuclear respiratory factor 1 co‐regulates AMPA glutamate receptor subunit 2 and cytochrome c oxidase: tight coupling of glutamatergic transmission and energy …
SS Dhar, HL Liang, MTT Wong‐Riley
Journal of neurochemistry 108 (6), 1595-1606, 2009
532009
Chromosome conformation capture of all 13 genomic Loci in the transcriptional regulation of the multisubunit bigenomic cytochrome C oxidase in neurons
SS Dhar, S Ongwijitwat, MTT Wong-Riley
Journal of biological chemistry 284 (28), 18644-18650, 2009
512009
Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4
Y Liu, S Qin, TY Chen, M Lei, SS Dhar, JC Ho, A Dong, P Loppnau, Y Li, ...
Nature communications 10 (1), 36, 2019
362019
Transcriptional coupling of synaptic transmission and energy metabolism: role of nuclear respiratory factor 1 in co-regulating neuronal nitric oxide synthase and cytochrome c …
SS Dhar, HL Liang, MTT Wong-Riley
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1793 (10), 1604-1613, 2009
352009
p38 mitogen‐activated protein kinase and calcium channels mediate signaling in depolarization‐induced activation of peroxisome proliferator‐activated receptor gamma coactivator …
HL Liang, SS Dhar, MTT Wong‐Riley
Journal of neuroscience research 88 (3), 640-649, 2010
322010
Neuron‐specific specificity protein 4 bigenomically regulates the transcription of all mitochondria‐ and nucleus‐encoded cytochrome c oxidase subunit genes in …
K Johar, A Priya, S Dhar, Q Liu, MTT Wong‐Riley
Journal of neurochemistry 127 (4), 496-508, 2013
312013
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Artículos 1–20