| Identification of myelodysplastic syndrome–specific genes by DNA microarray analysis with purified hematopoietic stem cell fraction A Miyazato, S Ueno, K Ohmine, M Ueda, K Yoshida, Y Yamashita, ... Blood, The Journal of the American Society of Hematology 98 (2), 422-427, 2001 | 216 | 2001 |
| A member of Forkhead family transcription factor, FKHRL1, is one of the downstream molecules of phosphatidylinositol 3-kinase-Akt activation pathway in erythropoietin signal … Y Kashii, M Uchida, K Kirito, M Tanaka, K Nishijima, M Toshima, T Ando, ... Blood, The Journal of the American Society of Hematology 96 (3), 941-949, 2000 | 197 | 2000 |
| Ruxolitinib versus best available therapy in patients with polycythemia vera: 80-week follow-up from the RESPONSE trial S Verstovsek, AM Vannucchi, M Griesshammer, T Masszi, S Durrant, ... Haematologica 101 (7), 821, 2016 | 184 | 2016 |
| Thrombopoietin stimulates Hoxb4 expression: an explanation for the favorable effects of TPO on hematopoietic stem cells K Kirito, N Fox, K Kaushansky Blood 102 (9), 3172-3178, 2003 | 166 | 2003 |
| Neolacto-series gangliosides induce granulocytic differentiation of human promyelocytic leukemia cell line HL-60. H Nojiri, S Kitagawa, M Nakamura, K Kirito, Y Enomoto, M Saito Journal of Biological Chemistry 263 (16), 7443-7446, 1988 | 156 | 1988 |
| A member of Forkhead transcription factor FKHRL1 is a downstream effector of STI571-induced cell cycle arrest in BCR-ABL-expressing cells N Komatsu, T Watanabe, M Uchida, M Mori, K Kirito, S Kikuchi, Q Liu, ... Journal of Biological Chemistry 278 (8), 6411-6419, 2003 | 138 | 2003 |
| Thrombopoietin regulates Bcl-xL gene expression through Stat5 and phosphatidylinositol 3-kinase activation pathways K Kirito, T Watanabe, K Sawada, H Endo, K Ozawa, N Komatsu Journal of Biological Chemistry 277 (10), 8329-8337, 2002 | 133 | 2002 |
| Long-term efficacy and safety of ruxolitinib versus best available therapy in polycythaemia vera (RESPONSE): 5-year follow up of a phase 3 study JJ Kiladjian, P Zachee, M Hino, F Pane, T Masszi, CN Harrison, R Mesa, ... The Lancet Haematology 7 (3), e226-e237, 2020 | 126 | 2020 |
| Thrombopoietin enhances expression of vascular endothelial growth factor (VEGF) in primitive hematopoietic cells through induction of HIF-1α K Kirito, N Fox, N Komatsu, K Kaushansky Blood 105 (11), 4258-4263, 2005 | 118 | 2005 |
| Characterization of stage progression in chronic myeloid leukemia by DNA microarray with purified hematopoietic stem cells K Ohmine, J Ota, M Ueda, S Ueno, K Yoshida, Y Yamashita, K Kirito, ... Oncogene 20 (57), 8249-8257, 2001 | 108 | 2001 |
| Romiplostim for the treatment of chronic immune thrombocytopenia in adult Japanese patients: a double-blind, randomized Phase III clinical trial Y Shirasugi, K Ando, K Miyazaki, Y Tomiyama, S Okamoto, M Kurokawa, ... International journal of hematology 94, 71-80, 2011 | 106 | 2011 |
| Identification of the human erythropoietin receptor region required for Stat1 and Stat3 activation K Kirito, K Nakajima, T Watanabe, M Uchida, M Tanaka, K Ozawa, ... Blood, The Journal of the American Society of Hematology 99 (1), 102-110, 2002 | 105 | 2002 |
| Recurrent CDC25C mutations drive malignant transformation in FPD/AML A Yoshimi, T Toya, M Kawazu, T Ueno, A Tsukamoto, H Iizuka, ... Nature communications 5 (1), 4770, 2014 | 98 | 2014 |
| Activation of extracellular signal‐regulated kinases ERK1 and ERK2 induces Bcl‐xL up‐regulation via inhibition of caspase activities in erythropoietin signaling M Mori, M Uchida, T Watanabe, K Kirito, K Hatake, K Ozawa, N Komatsu Journal of cellular physiology 195 (2), 290-297, 2003 | 98 | 2003 |
| Thrombopoietin induces HOXA9 nuclear transport in immature hematopoietic cells: potential mechanism by which the hormone favorably affects hematopoietic stem cells K Kirito, N Fox, K Kaushansky Molecular and cellular biology 24 (15), 6751-6762, 2004 | 84 | 2004 |
| FOXO3A as a key molecule for all-trans retinoic acid–induced granulocytic differentiation and apoptosis in acute promyelocytic leukemia Y Sakoe, K Sakoe, K Kirito, K Ozawa, N Komatsu Blood, The Journal of the American Society of Hematology 115 (18), 3787-3795, 2010 | 81 | 2010 |
| A distinct function of STAT proteins in erythropoietin signal transduction K Kirito, M Uchida, M Yamada, Y Miura, N Komatsu Journal of Biological Chemistry 272 (26), 16507-16513, 1997 | 79 | 1997 |
| Inhibition of hypoxia-inducible factor-1 function enhances the sensitivity of multiple myeloma cells to melphalan Y Hu, K Kirito, K Yoshida, T Mitsumori, K Nakajima, Y Nozaki, ... Molecular cancer therapeutics 8 (8), 2329-2338, 2009 | 74 | 2009 |
| A functional role of Stat3 in in vivo megakaryopoiesis K Kirito, M Osawa, H Morita, R Shimizu, M Yamamoto, A Oda, H Fujita, ... Blood, The Journal of the American Society of Hematology 99 (9), 3220-3227, 2002 | 71 | 2002 |
| Ganglioside GM3 Can Induce Megakaryocytoid Differentiation of Human Leukemia Cell Line K562 Cells M Nakamura, K Kirito, J Yamanoi, T Wainai, H Nojiri, M Saito Cancer research 51 (7), 1940-1945, 1991 | 71 | 1991 |
