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Alejandro Valbuena
Alejandro Valbuena
Centro de Biología Molecular Severo Ochoa (CBMSO, UAM-CSIC)
Dirección de correo verificada de cbm.csic.es
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On the remarkable mechanostability of scaffoldins and the mechanical clamp motif
A Valbuena, J Oroz, R Hervás, AM Vera, D Rodríguez, M Menéndez, ...
Proceedings of the National Academy of Sciences 106 (33), 13791-13796, 2009
1412009
Common features at the start of the neurodegeneration cascade
R Hervas, J Oroz, A Galera-Prat, O Goni, A Valbuena, AM Vera, ...
PLoS biology 10 (5), e1001335, 2012
762012
Nanomechanics of the cadherin ectodomain:“canalization” by Ca2+ binding results in a new mechanical element
J Oroz, A Valbuena, AM Vera, J Mendieta, P Gómez-Puertas, ...
Journal of Biological Chemistry 286 (11), 9405-9418, 2011
542011
Imaging and quantitation of a succession of transient intermediates reveal the reversible self-assembly pathway of a simple icosahedral virus capsid
M Medrano, MÁ Fuertes, A Valbuena, PJP Carrillo, A Rodríguez-Huete, ...
Journal of the American Chemical Society 138 (47), 15385-15396, 2016
442016
Mechanical properties of β-catenin revealed by single-molecule experiments
A Valbuena, AM Vera, J Oroz, M Menéndez, M Carrión-Vázquez
Biophysical journal 103 (8), 1744-1752, 2012
392012
Visualization of single molecules building a viral capsid protein lattice through stochastic pathways
A Valbuena, S Maity, MG Mateu, WH Roos
ACS nano 14 (7), 8724-8734, 2020
362020
Structural analysis of a temperature-induced transition in a viral capsid probed by HDX-MS
M Van de Waterbeemd, A Llauró, J Snijder, A Valbuena, ...
Biophysical Journal 112 (6), 1157-1165, 2017
352017
Conformational rearrangements in the transmembrane domain of CNGA1 channels revealed by single-molecule force spectroscopy
S Maity, M Mazzolini, M Arcangeletti, A Valbuena, P Fabris, M Lazzarino, ...
Nature communications 6 (1), 7093, 2015
302015
Structural basis for biologically relevant mechanical stiffening of a virus capsid by cavity-creating or spacefilling mutations
P Guerra, A Valbuena, J Querol-Audí, C Silva, M Castellanos, ...
Scientific reports 7 (1), 4101, 2017
282017
Amino acid side chains buried along intersubunit interfaces in a viral capsid preserve low mechanical stiffness associated with virus infectivity
PJP Carrillo, M Medrano, A Valbuena, A Rodríguez-Huete, M Castellanos, ...
ACS nano 11 (2), 2194-2208, 2017
262017
Quantification and modification of the equilibrium dynamics and mechanics of a viral capsid lattice self-assembled as a protein nanocoating
A Valbuena, MG Mateu
Nanoscale 7 (36), 14953-14964, 2015
242015
Quasi-simultaneous imaging/pulling analysis of single polyprotein molecules by atomic force microscopy
A Valbuena, J Oroz, AM Vera, A Gimeno, J Gomez-Herrero, ...
Review of Scientific Instruments 78 (11), 2007
232007
Long-range cooperative disassembly and aging during adenovirus uncoating
N Martín-González, P Ibáñez-Freire, Á Ortega-Esteban, M Laguna-Castro, ...
Physical Review X 11 (2), 021025, 2021
192021
Nanomechanics of tip-link cadherins
J Oroz, A Galera-Prat, R Hervás, A Valbuena, D Fernández-Bravo, ...
Scientific Reports 9 (1), 13306, 2019
182019
Mechanical stiffening of human rhinovirus by cavity-filling antiviral drugs
A Valbuena, A Rodríguez-Huete, MG Mateu
Nanoscale 10 (3), 1440-1452, 2018
182018
Kinetics of surface-driven self-assembly and fatigue-induced disassembly of a virus-based nanocoating
A Valbuena, MG Mateu
Biophysical Journal 112 (4), 663-673, 2017
182017
Thermostability of the Foot-and-Mouth Disease Virus Capsid Is Modulated by Lethal and Viability-Restoring Compensatory Amino Acid Substitutions
MGM Silvia López-Argüello, Verónica Rincón, Alicia Rodríguez-Huete ...
Journal of Virology, 2019
112019
Metamorphism in TDP-43 prion-like domain determines chaperone recognition
J Carrasco, R Antón, A Valbuena, D Pantoja-Uceda, M Mukhi, R Hervás, ...
Nature communications 14 (1), 466, 2023
102023
Structural determinants of mechanical resistance against breakage of a virus-based protein nanoparticle at a resolution of single amino acids
M Medrano, A Valbuena, A Rodríguez-Huete, MG Mateu
Nanoscale 11 (19), 9369-9383, 2019
92019
Antiviral compounds modulate elasticity, strength and material fatigue of a virus capsid framework
S Domínguez-Zotes, A Valbuena, MG Mateu
Biophysical Journal 121 (6), 919-931, 2022
72022
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Artículos 1–20