| Plasma membrane channels formed by connexins: their regulation and functions JC Sáez, VM Berthoud, MC Branes, AD Martínez, EC Beyer Physiological reviews 83 (4), 1359-1400, 2003 | 1482 | 2003 |
| Gap junctions: new tools, new answers, new questions MVL Bennett, LC Barrio, TA Bargiello, DC Spray, EL Hertzberg, JC Saez Neuron 6 (3), 305-320, 1991 | 1199 | 1991 |
| Hepatocyte gap junctions are permeable to the second messenger, inositol 1, 4, 5-trisphosphate, and to calcium ions. JC Saez, JA Connor, DC Spray, MV Bennett Proceedings of the National Academy of Sciences 86 (8), 2708-2712, 1989 | 719 | 1989 |
| Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture JE Contreras, HA Sánchez, EA Eugenín, D Speidel, M Theis, K Willecke, ... Proceedings of the National Academy of Sciences 99 (1), 495-500, 2002 | 656 | 2002 |
| Cx43 hemichannels and gap junction channels in astrocytes are regulated oppositely by proinflammatory cytokines released from activated microglia MA Retamal, N Froger, N Palacios-Prado, P Ezan, PJ Sáez, JC Sáez, ... Journal of Neuroscience 27 (50), 13781-13792, 2007 | 547 | 2007 |
| Gating and regulation of connexin 43 (Cx43) hemichannels JE Contreras, JC Sáez, FF Bukauskas, MVL Bennett Proceedings of the National Academy of Sciences 100 (20), 11388-11393, 2003 | 522 | 2003 |
| Connexin-based gap junction hemichannels: gating mechanisms JC Sáez, MA Retamal, D Basilio, FF Bukauskas, MVL Bennett Biochimica et Biophysica Acta (BBA)-Biomembranes 1711 (2), 215-224, 2005 | 507 | 2005 |
| New roles for astrocytes: gap junction hemichannels have something to communicate MVL Bennett, JE Contreras, FF Bukauskas, JC Sáez Trends in neurosciences 26 (11), 610-617, 2003 | 491 | 2003 |
| cAMP increases junctional conductance and stimulates phosphorylation of the 27-kDa principal gap junction polypeptide. JC Saez, DC Spray, AC Nairn, E Hertzberg, P Greengard, MV Bennett Proceedings of the National Academy of Sciences 83 (8), 2473-2477, 1986 | 434 | 1986 |
| ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels JA Orellana, N Froger, P Ezan, JX Jiang, MVL Bennett, CC Naus, ... Journal of neurochemistry 118 (5), 826-840, 2011 | 430 | 2011 |
| S-nitrosylation and permeation through connexin 43 hemichannels in astrocytes: induction by oxidant stress and reversal by reducing agents MA Retamal, CJ Cortés, L Reuss, MVL Bennett, JC Sáez Proceedings of the National Academy of Sciences 103 (12), 4475-4480, 2006 | 359 | 2006 |
| Amyloid β-induced death in neurons involves glial and neuronal hemichannels JA Orellana, KF Shoji, V Abudara, P Ezan, E Amigou, PJ Sáez, JX Jiang, ... Journal of Neuroscience 31 (13), 4962-4977, 2011 | 336 | 2011 |
| Role of connexin-based gap junction channels and hemichannels in ischemia-induced cell death in nervous tissue JE Contreras, HA Sánchez, LP Véliz, FF Bukauskas, MVL Bennett, ... Brain Research Reviews 47 (1-3), 290-303, 2004 | 311 | 2004 |
| Human connexin43 gap junction channels. Regulation of unitary conductances by phosphorylation. AP Moreno, JC Sáez, GI Fishman, DC Spray Circulation research 74 (6), 1050-1057, 1994 | 311 | 1994 |
| Modulation of brain hemichannels and gap junction channels by pro-inflammatory agents and their possible role in neurodegeneration JA Orellana, PJ Sáez, KF Shoji, KA Schalper, N Palacios–Prado, ... Antioxidants & redox signaling 11 (2), 369-399, 2009 | 285 | 2009 |
| Release of gliotransmitters through astroglial connexin 43 hemichannels is necessary for fear memory consolidation in the basolateral amygdala J Stehberg, JA Orellana Roca, JC Sáez | 275 | 2012 |
| Proteoglycans and glycosaminoglycans induce gap junction synthesis and function in primary liver cultures. DC Spray, M Fujita, JC Saez, H Choi, T Watanabe, E Hertzberg, ... The Journal of cell biology 105 (1), 541-551, 1987 | 274 | 1987 |
| Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles C Giaume, L Leybaert, C C. Naus, J C. Sáez Frontiers in pharmacology 4, 88, 2013 | 272 | 2013 |
| Microglia at brain stab wounds express connexin 43 and in vitro form functional gap junctions after treatment with interferon-γ and tumor necrosis factor-α EA Eugenín, D Eckardt, M Theis, K Willecke, MVL Bennett, JC Sáez Proceedings of the National Academy of Sciences 98 (7), 4190-4195, 2001 | 265 | 2001 |
| TNF-α plus IFN-γ induce connexin43 expression and formation of gap junctions between human monocytes/macrophages that enhance physiological responses EA Eugenín, MC Brañes, JW Berman, JC Sáez The Journal of Immunology 170 (3), 1320-1328, 2003 | 248 | 2003 |
Juan Andrés OrellanaAssociate Professor. Departamento de Neurología. Pontificia Universidad Católica de ChileVerified email at uc.cl
