Juan C Saez
Juan C Saez
Instituto de Neurociencias, Universidad de Valparaíso, Valparaíso, Chile (juancarlos.saez@uv.cl)
Verified email at uv.cl - Homepage
Cited by
Cited by
Plasma membrane channels formed by connexins: their regulation and functions
JC Sáez, VM Berthoud, MC Branes, AD Martinez, EC Beyer
Physiological reviews 83 (4), 1359-1400, 2003
Gap junctions: new tools, new answers, new questions
MVL Bennett, LC Barrio, TA Bargiello, DC Spray, EL Hertzberg, JC Saez
Neuron 6 (3), 305-320, 1991
Hepatocyte gap junctions are permeable to the second messenger, inositol 1, 4, 5-trisphosphate, and to calcium ions
JC Saez, JA Connor, DC Spray, MV Bennett
Proceedings of the National Academy of Sciences 86 (8), 2708-2712, 1989
Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture
JE Contreras, HA Sánchez, EA Eugenín, D Speidel, M Theis, K Willecke, ...
Proceedings of the National Academy of Sciences 99 (1), 495-500, 2002
Cx43 hemichannels and gap junction channels in astrocytes are regulated oppositely by proinflammatory cytokines released from activated microglia
MA Retamal, N Froger, N Palacios-Prado, P Ezan, PJ Sáez, JC Sáez, ...
Journal of Neuroscience 27 (50), 13781-13792, 2007
Connexin-based gap junction hemichannels: gating mechanisms
JC Sáez, MA Retamal, D Basilio, FF Bukauskas, MVL Bennett
Biochimica et Biophysica Acta (BBA)-Biomembranes 1711 (2), 215-224, 2005
Gating and regulation of connexin 43 (Cx43) hemichannels
JE Contreras, JC Sáez, FF Bukauskas, MVL Bennett
Proceedings of the National Academy of Sciences 100 (20), 11388-11393, 2003
New roles for astrocytes: gap junction hemichannels have something to communicate
MVL Bennett, JE Contreras, FF Bukauskas, JC Sáez
Trends in neurosciences 26 (11), 610-617, 2003
cAMP increases junctional conductance and stimulates phosphorylation of the 27-kDa principal gap junction polypeptide
JC Saez, DC Spray, AC Nairn, E Hertzberg, P Greengard, MV Bennett
Proceedings of the National Academy of Sciences 83 (8), 2473-2477, 1986
ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels
JA Orellana, N Froger, P Ezan, JX Jiang, MVL Bennett, CC Naus, ...
Journal of neurochemistry 118 (5), 826-840, 2011
S-nitrosylation and permeation through connexin 43 hemichannels in astrocytes: induction by oxidant stress and reversal by reducing agents
MA Retamal, CJ Cortés, L Reuss, MVL Bennett, JC Sáez
Proceedings of the National Academy of Sciences 103 (12), 4475-4480, 2006
Human connexin43 gap junction channels. Regulation of unitary conductances by phosphorylation.
AP Moreno, JC Sáez, GI Fishman, DC Spray
Circulation Research 74 (6), 1050-1057, 1994
Role of connexin-based gap junction channels and hemichannels in ischemia-induced cell death in nervous tissue
JE Contreras, HA Sánchez, LP Véliz, FF Bukauskas, MVL Bennett, ...
Brain Research Reviews 47 (1-3), 290-303, 2004
Amyloid β-induced death in neurons involves glial and neuronal hemichannels
JA Orellana, KF Shoji, V Abudara, P Ezan, E Amigou, PJ Sáez, JX Jiang, ...
Journal of Neuroscience 31 (13), 4962-4977, 2011
Proteoglycans and glycosaminoglycans induce gap junction synthesis and function in primary liver cultures.
DC Spray, M Fujita, JC Saez, H Choi, T Watanabe, E Hertzberg, ...
The Journal of cell biology 105 (1), 541-551, 1987
Modulation of brain hemichannels and gap junction channels by pro-inflammatory agents and their possible role in neurodegeneration
JA Orellana, PJ Sáez, KF Shoji, KA Schalper, N Palacios–Prado, ...
Antioxidants & redox signaling 11 (2), 369-399, 2009
Microglia at brain stab wounds express connexin 43 and in vitro form functional gap junctions after treatment with interferon-γ and tumor necrosis factor-α
EA Eugenín, D Eckardt, M Theis, K Willecke, MVL Bennett, JC Sáez
Proceedings of the National Academy of Sciences 98 (7), 4190-4195, 2001
TNF-α plus IFN-γ induce connexin43 expression and formation of gap junctions between human monocytes/macrophages that enhance physiological responses
EA Eugenín, MC Brañes, JW Berman, JC Sáez
The Journal of Immunology 170 (3), 1320-1328, 2003
Gap junctions. Multiplicity of controls in differentiated and undifferentiated cells and possible functional implications.
JC Saez, VM Berthoud, AP Moreno, DC Spray
Advances in second messenger and phosphoprotein research 27, 163-198, 1993
Release of gliotransmitters through astroglial connexin 43 hemichannels is necessary for fear memory consolidation in the basolateral amygdala
J Stehberg, R Moraga‐Amaro, C Salazar, A Becerra, C Echeverría, ...
The FASEB Journal 26 (9), 3649-3657, 2012
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