The single-cell transcriptional landscape of mammalian organogenesis J Cao, M Spielmann, X Qiu, X Huang, DM Ibrahim, AJ Hill, F Zhang, ... Nature 566 (7745), 496-502, 2019 | 2510 | 2019 |
Comprehensive single-cell transcriptional profiling of a multicellular organism J Cao, JS Packer, V Ramani, DA Cusanovich, C Huynh, R Daza, X Qiu, ... Science 357 (6352), 661-667, 2017 | 1263 | 2017 |
Joint profiling of chromatin accessibility and gene expression in thousands of single cells J Cao, DA Cusanovich, V Ramani, D Aghamirzaie, HA Pliner, AJ Hill, ... Science 361 (6409), 1380-1385, 2018 | 750 | 2018 |
A human cell atlas of fetal gene expression J Cao, DR O’day, HA Pliner, PD Kingsley, M Deng, RM Daza, MA Zager, ... Science 370 (6518), eaba7721, 2020 | 498 | 2020 |
A human cell atlas of fetal chromatin accessibility S Domcke, AJ Hill, RM Daza, J Cao, DR O’Day, HA Pliner, KA Aldinger, ... Science 370 (6518), eaba7612, 2020 | 290 | 2020 |
Massively multiplex chemical transcriptomics at single-cell resolution SR Srivatsan, JL McFaline-Figueroa, V Ramani, L Saunders, J Cao, ... Science 367 (6473), 45-51, 2020 | 243 | 2020 |
Suppression of the HSF 1‐mediated proteotoxic stress response by the metabolic stress sensor AMPK S Dai, Z Tang, J Cao, W Zhou, H Li, S Sampson, C Dai The EMBO journal 34 (3), 275-293, 2015 | 105 | 2015 |
Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle R Mosadeghi, KM Reichermeier, M Winkler, A Schreiber, JM Reitsma, ... Elife 5, e12102, 2016 | 97 | 2016 |
Sci-fate characterizes the dynamics of gene expression in single cells J Cao, W Zhou, F Steemers, C Trapnell, J Shendure Nature biotechnology 38 (8), 980-988, 2020 | 96 | 2020 |
HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth KH Su, J Cao, Z Tang, S Dai, Y He, SB Sampson, IJ Benjamin, C Dai Nature cell biology 18 (5), 527-539, 2016 | 91 | 2016 |
Proteotoxic stress of cancer: implication of the heat‐shock response in oncogenesis C Dai, S Dai, J Cao Journal of cellular physiology 227 (8), 2982-2987, 2012 | 88 | 2012 |
Systematic reconstruction of cellular trajectories across mouse embryogenesis C Qiu, J Cao, BK Martin, T Li, IC Welsh, S Srivatsan, X Huang, D Calderon, ... Nature genetics 54 (3), 328-341, 2022 | 83 | 2022 |
Optimized single-nucleus transcriptional profiling by combinatorial indexing BK Martin, C Qiu, E Nichols, M Phung, R Green-Gladden, S Srivatsan, ... Nature protocols 18 (1), 188-207, 2023 | 36 | 2023 |
A global view of aging and Alzheimer’s pathogenesis-associated cell population dynamics and molecular signatures in human and mouse brains A Sziraki, Z Lu, J Lee, G Banyai, S Anderson, A Abdulraouf, E Metzner, ... Nature Genetics 55 (12), 2104-2116, 2023 | 14 | 2023 |
Single-cell transcriptomics suggest distinct upstream drivers of IL-17A/F in hidradenitis versus psoriasis J Kim, J Lee, X Li, HS Lee, K Kim, V Chaparala, W Murphy, W Zhou, J Cao, ... Journal of Allergy and Clinical Immunology 152 (3), 656-666, 2023 | 13 | 2023 |
Expanding the binding specificity for RNA recognition by a PUF domain W Zhou, D Melamed, G Banyai, C Meyer, T Tuschl, M Wickens, J Cao, ... Nature Communications 12 (1), 5107, 2021 | 11 | 2021 |
A single-cell transcriptional timelapse of mouse embryonic development, from gastrula to pup C Qiu, BK Martin, IC Welsh, RM Daza, TM Le, X Huang, EK Nichols, ... bioRxiv, 2023 | 9 | 2023 |
De novo design of helical peptides to inhibit tumor necrosis factor-α by disrupting its trimer formation Q Shen, C Zhang, H Liu, Y Liu, J Cao, X Zhang, Y Liang, M Zhao, L Lai MedChemComm 7 (4), 725-729, 2016 | 9 | 2016 |
An optimized protocol for single cell transcriptional profiling by combinatorial indexing BK Martin, C Qiu, E Nichols, M Phung, R Green-Gladden, S Srivatsan, ... arXiv preprint arXiv:2110.15400, 2021 | 8 | 2021 |
Characterizing the temporal dynamics of gene expression in single cells with sci-fate J Cao, W Zhou, F Steemers, C Trapnell, J Shendure bioRxiv, 666081, 2019 | 8 | 2019 |