Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection W Jiang, MM Lederman, P Hunt, SF Sieg, K Haley, B Rodriguez, ... The Journal of infectious diseases 199 (8), 1177-1185, 2009 | 740 | 2009 |
Human epithelial β-defensins 2 and 3 inhibit HIV-1 replication ME Quiñones-Mateu, MM Lederman, Z Feng, B Chakraborty, J Weber, ... Aids 17 (16), F39-F48, 2003 | 587 | 2003 |
Human β-defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2 N Funderburg, MM Lederman, Z Feng, MG Drage, J Jadlowsky, ... Proceedings of the National Academy of Sciences 104 (47), 18631-18635, 2007 | 445 | 2007 |
Predictive value of plasma HIV RNA level on rate of CD4 T-cell decline in untreated HIV infection B Rodríguez, AK Sethi, VK Cheruvu, W Mackay, RJ Bosch, M Kitahata, ... Jama 296 (12), 1498-1506, 2006 | 432 | 2006 |
Perforin Expression Directly Ex Vivo by HIV-Specific CD8+ T-Cells Is a Correlate of HIV Elite Control AR Hersperger, F Pereyra, M Nason, K Demers, P Sheth, LY Shin, ... PLoS pathogens 6 (5), e1000917, 2010 | 408 | 2010 |
Immunologic failure despite suppressive antiretroviral therapy is related to activation and turnover of memory CD4 cells MM Lederman, L Calabrese, NT Funderburg, B Clagett, K Medvik, ... Journal of Infectious Diseases 204 (8), 1217-1226, 2011 | 351 | 2011 |
Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation NT Funderburg, E Mayne, SF Sieg, R Asaad, W Jiang, M Kalinowska, ... Blood, The Journal of the American Society of Hematology 115 (2), 161-167, 2010 | 337 | 2010 |
Shared monocyte subset phenotypes in HIV-1 infection and in uninfected subjects with acute coronary syndrome NT Funderburg, DA Zidar, C Shive, A Lioi, J Mudd, LW Musselwhite, ... Blood, The Journal of the American Society of Hematology 120 (23), 4599-4608, 2012 | 242 | 2012 |
Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1 A Biancotto, JC Grivel, SJ Iglehart, C Vanpouille, A Lisco, SF Sieg, ... Blood 109 (10), 4272-4279, 2007 | 232 | 2007 |
TLR9 stimulation drives naive B cells to proliferate and to attain enhanced antigen presenting function W Jiang, MM Lederman, CV Harding, B Rodriguez, RJ Mohner, SF Sieg European journal of immunology 37 (8), 2205-2213, 2007 | 201 | 2007 |
Toll-like receptor ligands induce human T cell activation and death, a model for HIV pathogenesis N Funderburg, AA Luciano, W Jiang, B Rodriguez, SF Sieg, ... PloS one 3 (4), e1915, 2008 | 189 | 2008 |
Interferon-α is the primary plasma type-I IFN in HIV-1 infection and correlates with immune activation and disease markers GAD Hardy, S Sieg, B Rodriguez, D Anthony, R Asaad, W Jiang, J Mudd, ... PloS one 8 (2), e56527, 2013 | 186 | 2013 |
Increased platelet and microparticle activation in HIV infection: upregulation of P-selectin and tissue factor expression E Mayne, NT Funderburg, SF Sieg, R Asaad, M Kalinowska, B Rodriguez, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 59 (4), 340-346, 2012 | 166 | 2012 |
CD8 T-cell expansion and inflammation linked to CMV coinfection in ART-treated HIV infection ML Freeman, JC Mudd, CL Shive, SA Younes, S Panigrahi, SF Sieg, ... Clinical Infectious Diseases 62 (3), 392-396, 2016 | 144 | 2016 |
Conversion of β-carotene into astaxanthin: Two separate enzymes or a bifunctional hydroxylase-ketolase protein? JF Martín, E Gudiña, JL Barredo Microbial Cell Factories 7, 1-10, 2008 | 122 | 2008 |
Oxidized LDL levels are increased in HIV infection and may drive monocyte activation DA Zidar, S Juchnowski, B Ferrari, B Clagett, HA Pilch-Cooper, S Rose, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 69 (2), 154-160, 2015 | 117 | 2015 |
Role of the Fas/Fas ligand apoptotic pathway in human immunodeficiency virus type 1 disease D Kaplan, S Sieg Journal of Virology 72 (8), 6279-6282, 1998 | 114 | 1998 |
IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection SA Younes, ML Freeman, JC Mudd, CL Shive, A Reynaldi, S Panigrahi, ... The Journal of clinical investigation 126 (7), 2745-2756, 2016 | 111 | 2016 |
The Toll‐like receptor 1/2 agonists Pam3CSK4 and human β‐defensin‐3 differentially induce interleukin‐10 and nuclear factor‐κB signalling patterns in human … NT Funderburg, JK Jadlowsky, MM Lederman, Z Feng, A Weinberg, ... Immunology 134 (2), 151-160, 2011 | 100 | 2011 |
HIV-1 infection impairs cell cycle progression of CD4+ T cells without affecting early activation responses SF Sieg, CV Harding, MM Lederman The Journal of Clinical Investigation 108 (5), 757-764, 2001 | 97 | 2001 |