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Pawel Paszek
Pawel Paszek
Institute of Fundamental Technological Research PAN
Dirección de correo verificada de ippt.pan.pl
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Pulsatile stimulation determines timing and specificity of NF-κB-dependent transcription
L Ashall, CA Horton, DE Nelson, P Paszek, CV Harper, K Sillitoe, S Ryan, ...
Science 324 (5924), 242-246, 2009
6582009
Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer’s disease in rodent models
MJD Daniels, J Rivers-Auty, T Schilling, NG Spencer, W Watremez, ...
Nature communications 7 (1), 12504, 2016
3982016
Mathematical model of NF-κB regulatory module
T Lipniacki, P Paszek, AR Brasier, B Luxon, M Kimmel
Journal of theoretical biology 228 (2), 195-215, 2004
3912004
Inflammasome-dependent IL-1β release depends upon membrane permeabilisation
F Martín-Sánchez, C Diamond, M Zeitler, AI Gomez, A Baroja-Mazo, ...
Cell Death & Differentiation 23 (7), 1219-1231, 2016
2662016
Population robustness arising from cellular heterogeneity
P Paszek, S Ryan, L Ashall, K Sillitoe, CV Harper, DG Spiller, DA Rand, ...
Proceedings of the National Academy of Sciences 107 (25), 11644-11649, 2010
2222010
Physiological levels of TNFα stimulation induce stochastic dynamics of NF-κB responses in single living cells
DA Turner, P Paszek, DJ Woodcock, DE Nelson, CA Horton, Y Wang, ...
Journal of cell science 123 (16), 2834-2843, 2010
1612010
Transcriptional stochasticity in gene expression
T Lipniacki, P Paszek, A Marciniak-Czochra, AR Brasier, M Kimmel
Journal of theoretical biology 238 (2), 348-367, 2006
1572006
Stochastic regulation in early immune response
T Lipniacki, P Paszek, AR Brasier, BA Luxon, M Kimmel
Biophysical journal 90 (3), 725-742, 2006
1312006
Single TNFα trimers mediating NF-κ B activation: stochastic robustness of NF-κ B signaling
T Lipniacki, K Puszynski, P Paszek, AR Brasier, M Kimmel
BMC bioinformatics 8, 1-20, 2007
972007
Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states
A Adamson, C Boddington, P Downton, W Rowe, J Bagnall, C Lam, ...
Nature communications 7 (1), 12057, 2016
812016
Integration of kinase and calcium signaling at the level of chromatin underlies inducible gene activation in T cells
R Brignall, P Cauchy, SL Bevington, B Gorman, AO Pisco, J Bagnall, ...
The Journal of Immunology 199 (8), 2652-2667, 2017
632017
Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation
JM Ankers, R Awais, NA Jones, J Boyd, S Ryan, AD Adamson, CV Harper, ...
Elife 5, e10473, 2016
572016
Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation
J Bagnall, C Boddington, H England, R Brignall, P Downton, Z Alsoufi, ...
Science signaling 11 (540), eaaf3998, 2018
562018
Dynamic organisation of prolactin gene expression in living pituitary tissue
CV Harper, K Featherstone, S Semprini, S Friedrichsen, J McNeilly, ...
Journal of Cell Science 123 (3), 424-430, 2010
552010
Oscillatory control of signalling molecules
P Paszek, DA Jackson, MRH White
Current opinion in genetics & development 20 (6), 670-676, 2010
522010
Interactions among oscillatory pathways in NF-kappa B signaling
Y Wang, P Paszek, CA Horton, DB Kell, MRH White, DS Broomhead, ...
BMC systems biology 5, 1-11, 2011
472011
Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation
NE Phillips, CS Manning, T Pettini, V Biga, E Marinopoulou, P Stanley, ...
Elife 5, e16118, 2016
462016
Modeling stochasticity in gene regulation: characterization in the terms of the underlying distribution function
P Paszek
Bulletin of Mathematical Biology 69, 1567-1601, 2007
452007
Quantitative dynamic imaging of immune cell signalling using lentiviral gene transfer
J Bagnall, C Boddington, J Boyd, R Brignall, W Rowe, NA Jones, ...
Integrative Biology 7 (6), 713-725, 2015
432015
Anti-inflammatory effects of infliximab in mice are independent of tumour necrosis factor α neutralization
BM Assas, SE Levison, M Little, H England, L Battrick, J Bagnall, ...
Clinical & Experimental Immunology 187 (2), 225-233, 2017
382017
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Artículos 1–20