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John A. Roque III
John A. Roque III
UNCG, UTA, UNC
Dirección de correo verificada de mazenanimalhealth.com - Página principal
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Transition metal complexes and photodynamic therapy from a tumor-centered approach: challenges, opportunities, and highlights from the development of TLD1433
S Monro, KL Colon, H Yin, J Roque III, P Konda, S Gujar, RP Thummel, ...
Chemical reviews 119 (2), 797-828, 2018
10402018
Near-infrared absorbing Ru (II) complexes act as immunoprotective photodynamic therapy (PDT) agents against aggressive melanoma
LM Lifshits, JA Roque III, P Konda, S Monro, HD Cole, D von Dohlen, ...
Chemical Science 11 (43), 11740-11762, 2020
772020
Breaking the barrier: an osmium photosensitizer with unprecedented hypoxic phototoxicity for real world photodynamic therapy
JA Roque, PC Barrett, HD Cole, LM Lifshits, G Shi, S Monro, ...
Chemical science 11 (36), 9784-9806, 2020
682020
Anticancer agent with inexplicable potency in extreme hypoxia: Characterizing a light-triggered ruthenium ubertoxin
HD Cole, JA Roque III, G Shi, LM Lifshits, E Ramasamy, PC Barrett, ...
Journal of the American Chemical Society 144 (22), 9543-9547, 2021
512021
New class of homoleptic and heteroleptic bis (terpyridine) iridium (III) complexes with strong photodynamic therapy effects
B Liu, S Monro, Z Li, MA Jabed, D Ramirez, CG Cameron, K Colón, ...
ACS applied bio materials 2 (7), 2964-2977, 2019
482019
Strained, photoejecting Ru (II) complexes that are cytotoxic under hypoxic conditions
J Roque III, D Havrylyuk, PC Barrett, T Sainuddin, J McCain, K Colón, ...
Photochemistry and photobiology 96 (2), 327-339, 2020
442020
Photophysical properties and photobiological activities of ruthenium (II) complexes bearing π-expansive cyclometalating ligands with thienyl groups
J McCain, KL Colón, PC Barrett, SMA Monro, T Sainuddin, J Roque III, ...
Inorganic chemistry 58 (16), 10778-10790, 2019
392019
Os (II) oligothienyl complexes as a hypoxia-active photosensitizer class for photodynamic therapy
JA Roque III, PC Barrett, HD Cole, LM Lifshits, E Bradner, G Shi, ...
Inorganic chemistry 59 (22), 16341-16360, 2020
382020
Predictive strength of photophysical measurements for in vitro photobiological activity in a series of Ru (II) polypyridyl complexes derived from π-extended ligands
C Reichardt, S Monro, FH Sobotta, KL Colón, T Sainuddin, M Stephenson, ...
Inorganic chemistry 58 (5), 3156-3166, 2019
372019
Intraligand excited states turn a ruthenium oligothiophene complex into a light-triggered Ubertoxin with anticancer effects in extreme hypoxia
JA Roque III, HD Cole, PC Barrett, LM Lifshits, RO Hodges, S Kim, ...
Journal of the American Chemical Society 144 (18), 8317-8336, 2022
342022
TLD1433-Mediated photodynamic therapy with an optical surface applicator in the treatment of lung cancer cells in vitro
S Chamberlain, HD Cole, J Roque III, D Bellnier, SA McFarland, ...
Pharmaceuticals 13 (7), 137, 2020
282020
Discovery of immunogenic cell death-inducing ruthenium-based photosensitizers for anticancer photodynamic therapy
P Konda, LM Lifshits, JA Roque III, HD Cole, CG Cameron, SA McFarland, ...
Oncoimmunology 10 (1), 1863626, 2021
262021
Bis [pyrrolyl Ru (ii)] triads: a new class of photosensitizers for metal–organic photodynamic therapy
DA Smithen, S Monro, M Pinto, J Roque, RM Diaz-Rodriguez, H Yin, ...
Chemical Science 11 (44), 12047-12069, 2020
252020
Fine‐Feature Modifications to Strained Ruthenium Complexes Radically Alter Their Hypoxic Anticancer Activity
HD Cole, JA Roque III, LM Lifshits, R Hodges, PC Barrett, D Havrylyuk, ...
Photochemistry and photobiology 98 (1), 73-84, 2022
212022
Rapid and efficient pesticide detection via cyclodextrin-promoted energy transfer
N Serio, J Roque, A Badwal, M Levine
Analyst 140 (22), 7503-7507, 2015
202015
Photodynamic therapy of melanoma with new, structurally similar, NIR-absorbing ruthenium (II) complexes promotes tumor growth control via distinct hallmarks of immunogenic cell …
P Konda, JA Roque III, LM Lifshits, A Alcos, E Azzam, G Shi, CG Cameron, ...
American Journal of Cancer Research 12 (1), 210, 2022
192022
Synthesis, Characterization and Photobiological Studies of Ru(II) Dyads Derived from α‐Oligothiophene Derivatives of 1,10‐Phenanthroline
S Monro, CG Cameron, X Zhu, KL Colon, H Yin, T Sainuddin, M Hetu, ...
Photochemistry and photobiology 95 (1), 267-279, 2019
182019
It Takes Three to Tango: The Length of the Oligothiophene Chain Determines the Nature of the Long‐Lived Excited State and the Resulting Photocytotoxicity of a Ruthenium (II …
A Chettri, JA Roque III, KRA Schneider, HD Cole, CG Cameron, ...
ChemPhotoChem 5 (5), 421-425, 2021
162021
Intracellular photophysics of an osmium complex bearing an oligothiophene extended ligand
KRA Schneider, A Chettri, HD Cole, K Reglinski, J Brückmann, ...
Chemistry–A European Journal 26 (65), 14844-14851, 2020
152020
Cyclodextrin-promoted detection of aromatic toxicants and toxicant metabolites in urine
DJ DiScenza, L Gareau, N Serio, J Roque, L Prignano, M Verderame, ...
Analytical Chemistry Letters 6 (4), 345-353, 2016
132016
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