Transition metal complexes and photodynamic therapy from a tumor-centered approach: challenges, opportunities, and highlights from the development of TLD1433 S Monro, KL Colon, H Yin, J Roque III, P Konda, S Gujar, RP Thummel, ... Chemical reviews 119 (2), 797-828, 2018 | 1040 | 2018 |
Near-infrared absorbing Ru (II) complexes act as immunoprotective photodynamic therapy (PDT) agents against aggressive melanoma LM Lifshits, JA Roque III, P Konda, S Monro, HD Cole, D von Dohlen, ... Chemical Science 11 (43), 11740-11762, 2020 | 77 | 2020 |
Breaking the barrier: an osmium photosensitizer with unprecedented hypoxic phototoxicity for real world photodynamic therapy JA Roque, PC Barrett, HD Cole, LM Lifshits, G Shi, S Monro, ... Chemical science 11 (36), 9784-9806, 2020 | 68 | 2020 |
Anticancer agent with inexplicable potency in extreme hypoxia: Characterizing a light-triggered ruthenium ubertoxin HD Cole, JA Roque III, G Shi, LM Lifshits, E Ramasamy, PC Barrett, ... Journal of the American Chemical Society 144 (22), 9543-9547, 2021 | 51 | 2021 |
New class of homoleptic and heteroleptic bis (terpyridine) iridium (III) complexes with strong photodynamic therapy effects B Liu, S Monro, Z Li, MA Jabed, D Ramirez, CG Cameron, K Colón, ... ACS applied bio materials 2 (7), 2964-2977, 2019 | 48 | 2019 |
Strained, photoejecting Ru (II) complexes that are cytotoxic under hypoxic conditions J Roque III, D Havrylyuk, PC Barrett, T Sainuddin, J McCain, K Colón, ... Photochemistry and photobiology 96 (2), 327-339, 2020 | 44 | 2020 |
Photophysical properties and photobiological activities of ruthenium (II) complexes bearing π-expansive cyclometalating ligands with thienyl groups J McCain, KL Colón, PC Barrett, SMA Monro, T Sainuddin, J Roque III, ... Inorganic chemistry 58 (16), 10778-10790, 2019 | 39 | 2019 |
Os (II) oligothienyl complexes as a hypoxia-active photosensitizer class for photodynamic therapy JA Roque III, PC Barrett, HD Cole, LM Lifshits, E Bradner, G Shi, ... Inorganic chemistry 59 (22), 16341-16360, 2020 | 38 | 2020 |
Predictive strength of photophysical measurements for in vitro photobiological activity in a series of Ru (II) polypyridyl complexes derived from π-extended ligands C Reichardt, S Monro, FH Sobotta, KL Colón, T Sainuddin, M Stephenson, ... Inorganic chemistry 58 (5), 3156-3166, 2019 | 37 | 2019 |
Intraligand excited states turn a ruthenium oligothiophene complex into a light-triggered Ubertoxin with anticancer effects in extreme hypoxia JA Roque III, HD Cole, PC Barrett, LM Lifshits, RO Hodges, S Kim, ... Journal of the American Chemical Society 144 (18), 8317-8336, 2022 | 34 | 2022 |
TLD1433-Mediated photodynamic therapy with an optical surface applicator in the treatment of lung cancer cells in vitro S Chamberlain, HD Cole, J Roque III, D Bellnier, SA McFarland, ... Pharmaceuticals 13 (7), 137, 2020 | 28 | 2020 |
Discovery of immunogenic cell death-inducing ruthenium-based photosensitizers for anticancer photodynamic therapy P Konda, LM Lifshits, JA Roque III, HD Cole, CG Cameron, SA McFarland, ... Oncoimmunology 10 (1), 1863626, 2021 | 26 | 2021 |
Bis [pyrrolyl Ru (ii)] triads: a new class of photosensitizers for metal–organic photodynamic therapy DA Smithen, S Monro, M Pinto, J Roque, RM Diaz-Rodriguez, H Yin, ... Chemical Science 11 (44), 12047-12069, 2020 | 25 | 2020 |
Fine‐Feature Modifications to Strained Ruthenium Complexes Radically Alter Their Hypoxic Anticancer Activity† HD Cole, JA Roque III, LM Lifshits, R Hodges, PC Barrett, D Havrylyuk, ... Photochemistry and photobiology 98 (1), 73-84, 2022 | 21 | 2022 |
Rapid and efficient pesticide detection via cyclodextrin-promoted energy transfer N Serio, J Roque, A Badwal, M Levine Analyst 140 (22), 7503-7507, 2015 | 20 | 2015 |
Photodynamic therapy of melanoma with new, structurally similar, NIR-absorbing ruthenium (II) complexes promotes tumor growth control via distinct hallmarks of immunogenic cell … P Konda, JA Roque III, LM Lifshits, A Alcos, E Azzam, G Shi, CG Cameron, ... American Journal of Cancer Research 12 (1), 210, 2022 | 19 | 2022 |
Synthesis, Characterization and Photobiological Studies of Ru(II) Dyads Derived from α‐Oligothiophene Derivatives of 1,10‐Phenanthroline S Monro, CG Cameron, X Zhu, KL Colon, H Yin, T Sainuddin, M Hetu, ... Photochemistry and photobiology 95 (1), 267-279, 2019 | 18 | 2019 |
It Takes Three to Tango: The Length of the Oligothiophene Chain Determines the Nature of the Long‐Lived Excited State and the Resulting Photocytotoxicity of a Ruthenium (II … A Chettri, JA Roque III, KRA Schneider, HD Cole, CG Cameron, ... ChemPhotoChem 5 (5), 421-425, 2021 | 16 | 2021 |
Intracellular photophysics of an osmium complex bearing an oligothiophene extended ligand KRA Schneider, A Chettri, HD Cole, K Reglinski, J Brückmann, ... Chemistry–A European Journal 26 (65), 14844-14851, 2020 | 15 | 2020 |
Cyclodextrin-promoted detection of aromatic toxicants and toxicant metabolites in urine DJ DiScenza, L Gareau, N Serio, J Roque, L Prignano, M Verderame, ... Analytical Chemistry Letters 6 (4), 345-353, 2016 | 13 | 2016 |