| Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis RL Levine, M Wadleigh, J Cools, BL Ebert, G Wernig, BJP Huntly, ... Cancer cell 7 (4), 387-397, 2005 | 3830 | 2005 |
| Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2 J Nangalia, CE Massie, EJ Baxter, FL Nice, G Gundem, DC Wedge, ... New England Journal of Medicine 369 (25), 2391-2405, 2013 | 2127 | 2013 |
| Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl E Weisberg, PW Manley, W Breitenstein, J Brüggen, SW Cowan-Jacob, ... Cancer cell 7 (2), 129-141, 2005 | 1929 | 2005 |
| FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress Z Tothova, R Kollipara, BJ Huntly, BH Lee, DH Castrillon, DE Cullen, ... Cell 128 (2), 325-339, 2007 | 1782 | 2007 |
| Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia MA Dawson, RK Prinjha, A Dittmann, G Giotopoulos, M Bantscheff, ... Nature 478 (7370), 529-533, 2011 | 1698 | 2011 |
| Leukaemia stem cells and the evolution of cancer-stem-cell research BJP Huntly, DG Gilliland Nature Reviews Cancer 5 (4), 311-321, 2005 | 870 | 2005 |
| MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors BJP Huntly, H Shigematsu, K Deguchi, BH Lee, S Mizuno, N Duclos, ... Cancer cell 6 (6), 587-596, 2004 | 854 | 2004 |
| Cancer stem cell definitions and terminology: the devil is in the details P Valent, D Bonnet, R De Maria, T Lapidot, M Copland, JV Melo, ... Nature Reviews Cancer 12 (11), 767-775, 2012 | 814 | 2012 |
| A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia K Tzelepis, H Koike-Yusa, E De Braekeleer, Y Li, E Metzakopian, ... Cell reports 17 (4), 1193-1205, 2016 | 638 | 2016 |
| Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini, ASH Da Costa, ... Nature 537 (7621), 544-547, 2016 | 523 | 2016 |
| BET inhibitor resistance emerges from leukaemia stem cells CY Fong, O Gilan, EYN Lam, AF Rubin, S Ftouni, D Tyler, K Stanley, ... Nature 525 (7570), 538-542, 2015 | 514 | 2015 |
| Molecular landscape of acute myeloid leukemia in younger adults and its clinical relevance D Grimwade, A Ivey, BJP Huntly Blood, The Journal of the American Society of Hematology 127 (1), 29-41, 2016 | 510 | 2016 |
| The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia RL Levine, M Loriaux, BJP Huntly, ML Loh, M Beran, E Stoffregen, ... Blood 106 (10), 3377-3379, 2005 | 498 | 2005 |
| Population dynamics of normal human blood inferred from somatic mutations H Lee-Six, NF Øbro, MS Shepherd, S Grossmann, K Dawson, M Belmonte, ... Nature 561 (7724), 473-478, 2018 | 496 | 2018 |
| Targeting epigenetic readers in cancer MA Dawson, T Kouzarides, BJP Huntly New England Journal of Medicine 367 (7), 647-657, 2012 | 482 | 2012 |
| Large deletions at the t (9; 22) breakpoint are common and may identify a poor-prognosis subgroup of patients with chronic myeloid leukemia PB Sinclair, EP Nacheva, M Leversha, N Telford, J Chang, A Reid, ... Blood, The Journal of the American Society of Hematology 95 (3), 738-743, 2000 | 393 | 2000 |
| Mutation of JAK2 in the myeloproliferative disorders: timing, clonality studies, cytogenetic associations, and role in leukemic transformation PJ Campbell, EJ Baxter, PA Beer, LM Scott, AJ Bench, BJP Huntly, ... Blood 108 (10), 3548-3555, 2006 | 377 | 2006 |
| Reprogramming of T cells to natural killer–like cells upon Bcl11b deletion P Li, S Burke, J Wang, X Chen, M Ortiz, SC Lee, D Lu, L Campos, ... Science 329 (5987), 85-89, 2010 | 372 | 2010 |
| Deletions of the derivative chromosome 9 occur at the time of the Philadelphia translocation and provide a powerful and independent prognostic indicator in chronic myeloid leukemia BJP Huntly, AG Reid, AJ Bench, LJ Campbell, N Telford, P Shepherd, ... Blood, The Journal of the American Society of Hematology 98 (6), 1732-1738, 2001 | 296 | 2001 |
| FLT3 mutations confer enhanced proliferation and survival properties to multipotent progenitors in a murine model of chronic myelomonocytic leukemia BH Lee, Z Tothova, RL Levine, K Anderson, N Buza-Vidas, DE Cullen, ... Cancer cell 12 (4), 367-380, 2007 | 251 | 2007 |
