Raul Araya-Secchi

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Perez-Acle TomasComputational Biology Lab (DLab)Verified email at dlab.cl
Dr. Carlos F. Lagos, PhDFacultad de Medicina y Ciencia, Universidad San Sebastián, ChileVerified email at uss.cl
Jose Antonio GarateUniversidad de ValparaisoVerified email at uv.cl
Yoshie NaruiThe Ohio State UniversityVerified email at osu.edu
Marcos SotomayorAssociate Professor, Chemistry and Biochemistry Department, The Ohio State UniversityVerified email at osu.edu
Agustin D MartinezCentro Interdisciplinario de Neurociencia de Valparaíso, Universidad de ValparaísoVerified email at uv.cl
Ruhong ZhouQiushi Chair Professor, Zhejiang University; Adjunct Professor, Columbia UniversityVerified email at columbia.edu
Tien HuynhIBM Thomas J. Watson Research CenterVerified email at us.ibm.com
Pedro De-la-TorrePostdoctoral Fellow, Massachusetts Eye and Ear, Department of Otolaryngology, Harvard Medical SchoolVerified email at meei.harvard.edu
Isaac E. García CarrilloAssociate Professor, Universidad de Valparaiso, PhD, Investigator, Centro Interdisciplinario deVerified email at uv.cl
Seung-gu KangResearch Staff Member, IBM T.J. Watson Research CenterVerified email at us.ibm.com
Angel González WongPosdoctoral ResearcherVerified email at uab.cat
Yerko EscalonaInstitute of Molecular Modeling and Simulation (MMS), BOKU, Vienna, AustriaVerified email at boku.ac.at
David HolmesDirector, Center for Bioinformatics and Genome Biology, Fundacion Ciencia y VidaVerified email at cienciavida.cl
Lahiru Neth WimalasenaPhD Student, Emory University/Georgia InstituteVerified email at emory.edu
Eric C. BeyerProfessor of Pediatrics, University of ChicagoVerified email at uchicago.edu
Oscar JaraUniversity of ChicagoVerified email at uchicago.edu
Deqiang WangChongqing Institute of Green and Intelligent Technology,Chinese Academy of SciencesVerified email at cigit.ac.cn
benlong wangProfessor of Engineering Mechanics, Shanghai Jiao Tong UniveristyVerified email at sjtu.edu.cn
Avinash JaiganeshThe Ohio State University, Northwestern University, XTAL BiostructuresVerified email at buckeyemail.osu.edu

Raul Araya-Secchi

Facultad de Ingeniería y Tecnología. Universidad San Sebastian

Verified email at uss.cl

Structural Biology Biophysics Molecular Dynamics Simulations Membrane Proteins


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Critical role of the first transmembrane domain of Cx26 in regulating oligomerization and function O Jara, R Acuña, IE García, J Maripillán, V Figueroa, JC Sáez, ... Molecular biology of the cell 23 (17), 3299-3311, 2012	43	2012
Computational modeling study of functional microdomains in cannabinoid receptor type 1 A Gonzalez, LS Duran, R Araya-Secchi, JA Garate, CD Pessoa-Mahana, ... Bioorganic & medicinal chemistry 16 (8), 4378-4389, 2008	31	2008
An elastic element in the protocadherin-15 tip link of the inner ear R Araya-Secchi, BL Neel, M Sotomayor Nature communications 7 (1), 1-14, 2016	26	2016
Characterization of a novel water pocket inside the human Cx26 hemichannel structure R Araya-Secchi, T Perez-Acle, S Kang, T Huynh, A Bernardin, Y Escalona, ... Biophysical journal 107 (3), 599-612, 2014	26	2014
Dual inhibitory pathways of metallofullerenol Gd@ C 82 (OH) 22 on matrix metalloproteinase-2: molecular insight into drug-like nanomedicine S Kang, R Araya-Secchi, D Wang, B Wang, T Huynh, R Zhou Scientific reports 4 (1), 1-8, 2014	20	2014
Beyond cell–cell adhesion: Sensational cadherins for hearing and balance A Jaiganesh, Y Narui, R Araya-Secchi, M Sotomayor Cold Spring Harbor perspectives in biology 10 (9), a029280, 2018	19	2018
Molecular dynamics study of the archaeal aquaporin AqpM R Araya-Secchi, JA Garate, DS Holmes, T Perez-Acle BMC genomics 12 (4), 1-13, 2011	14	2011
1-benzoyl-2-(2-nitrophenyl)-1H-benzimidazole derivatives: A novel approach to the development of new HIV-1 reverse transcriptase inhibitors D Vásquez, CF Lagos, J Mella-Raipán, L González, R Ebensperger, ... Journal of the Chilean Chemical Society 52 (4), 1281-1287, 2007	13	2007
Multidomain convergence of Argonaute during RISC assembly correlates with the formation of internal water clusters MS Park, R Araya-Secchi, JA Brackbill, HD Phan, AC Kehling, ... Molecular cell 75 (4), 725-740. e6, 2019	11	2019
Exploring the membrane potential of simple dual-membrane systems as models for gap-junction channels Y Escalona, JA Garate, R Araya-Secchi, T Huynh, R Zhou, T Perez-Acle Biophysical journal 110 (12), 2678-2688, 2016	11	2016
An eleven amino acid residue deletion expands the substrate specificity of acetyl xylan esterase II (AXE II) from Penicillium purpurogenum M Colombres, JA Garate, CF Lagos, R Araya-Secchi, P Norambuena, ... Journal of computer-aided molecular design 22 (1), 19-28, 2008	9	2008
A mechanically weak extracellular membrane-adjacent domain induces dimerization of protocadherin-15 P De-la-Torre, D Choudhary, R Araya-Secchi, Y Narui, M Sotomayor Biophysical journal 115 (12), 2368-2385, 2018	8	2018
Molecular modeling of Trypanosoma cruzi glutamate cysteine ligase and investigation of its interactions with glutathione CF Lagos, R Araya-Secchi, P Thomas, T Pérez-Acle, RA Tapia, CO Salas Journal of molecular modeling 18 (5), 2055-2064, 2012	4	2012
Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception D Choudhary, Y Narui, BL Neel, LN Wimalasena, CF Klanseck, ... Proceedings of the National Academy of Sciences 117 (40), 24837-24848, 2020	3	2020
The intracellular lipid-binding domain of human Na+/H+ exchanger 1 forms a lipid-protein co-structure essential for activity R Hendus-Altenburger, J Vogensen, ES Pedersen, A Luchini, ... Communications biology 3 (1), 1-18, 2020	2	2020
Molecular dynamics simulations of Cx26-Wt and deafness related mutants M34A, A40G and V37I R Araya-Secchi, CF Lagos, F Abarca, AD Martinez, T Perez-Acle Biophysical Journal 102 (3), 106a-107a, 2012	2	2012
Protein function in extremely acidic conditions: Molecular simulations of a predicted aquaporin and a potassium channel in Acidithiobacillus ferrooxidans F Duarte, R Araya-Secchi, W González, T Perez-Acle, D González-Nilo, ... Advanced Materials Research 71, 211-214, 2009	2	2009
Structures and simulations of membrane adjacent fragments of Protocadherin-15 P De-la-Torre, Y Narui, D Choudhary, R Araya-Secchi, M Sotomayor Biophysical Journal 116 (3), 459a, 2019	1	2019
Functional characterization of the ATPase-like activity displayed by a catalytic amyloid C Castillo-Caceres, E Duran-Meza, E Nova, R Araya-Secchi, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1865 (1), 129729, 2021		2021
Exploring the Protein-Membrane Interactions on the Intracellular Side of PRLR R Araya-Secchi, K Bugge, BB Kragelund, L Arleth Biophysical Journal 118 (3), 57a, 2020		2020

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