| Towards a rigorous assessment of systems biology models: the DREAM3 challenges RJ Prill, D Marbach, J Saez-Rodriguez, PK Sorger, LG Alexopoulos, ... PloS one 5 (2), e9202, 2010 | 458 | 2010 |
| The pericellular matrix as a transducer of biomechanical and biochemical signals in articular cartilage F Guilak, LG Alexopoulos, ML Upton, I Youn, JB Choi, LI Cao, LA Setton, ... Annals of the New York Academy of Sciences 1068 (1), 498-512, 2006 | 402 | 2006 |
| Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction J Saez‐Rodriguez, LG Alexopoulos, J Epperlein, R Samaga, ... Molecular systems biology 5 (1), 331, 2009 | 367 | 2009 |
| Determination of the Poisson's ratio of the cell: recovery properties of chondrocytes after release from complete micropipette aspiration WR Trickey, FPT Baaijens, TA Laursen, LG Alexopoulos, F Guilak Journal of biomechanics 39 (1), 78-87, 2006 | 268 | 2006 |
| The biomechanical role of the chondrocyte pericellular matrix in articular cartilage LG Alexopoulos, LA Setton, F Guilak Acta biomaterialia 1 (3), 317-325, 2005 | 251 | 2005 |
| Alterations in the mechanical properties of the human chondrocyte pericellular matrix with osteoarthritis LG Alexopoulos, MA Haider, TP Vail, F Guilak Journal of biomechanical engineering 125 (3), 323-333, 2003 | 242 | 2003 |
| Osteoarthritic changes in the biphasic mechanical properties of the chondrocyte pericellular matrix in articular cartilage LG Alexopoulos, GM Williams, ML Upton, LA Setton, F Guilak Journal of biomechanics 38 (3), 509-517, 2005 | 226 | 2005 |
| The logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput data R Samaga, J Saez-Rodriguez, LG Alexopoulos, PK Sorger, S Klamt PLoS computational biology 5 (8), e1000438, 2009 | 217 | 2009 |
| Developmental and osteoarthritic changes in Col6a1‐knockout mice: Biomechanics of type VI collagen in the cartilage pericellular matrix LG Alexopoulos, I Youn, P Bonaldo, F Guilak Arthritis & Rheumatism: Official Journal of the American College of …, 2009 | 198 | 2009 |
| Hyper-osmotic stress induces volume change and calcium transients in chondrocytes by transmembrane, phospholipid, and G-protein pathways GR Erickson, LG Alexopoulos, F Guilak Journal of biomechanics 34 (12), 1527-1535, 2001 | 162 | 2001 |
| Comparing Signaling Networks between Normal and Transformed Hepatocytes Using Discrete Logical ModelsComparative Networks of Normal and Transformed Hepatocytes J Saez-Rodriguez, LG Alexopoulos, MS Zhang, MK Morris, ... Cancer research 71 (16), 5400-5411, 2011 | 158 | 2011 |
| Automated standardized pupillometry with optical method for purposes of clinical practice and research F Fotiou, KN Fountoulakis, A Goulas, L Alexopoulos, A Palikaras Clinical Physiology 20 (5), 336-347, 2000 | 157 | 2000 |
| Crowdsourcing network inference: the DREAM predictive signaling network challenge RJ Prill, J Saez-Rodriguez, LG Alexopoulos, PK Sorger, G Stolovitzky Science signaling 4 (189), mr7-mr7, 2011 | 145 | 2011 |
| Identifying drug effects via pathway alterations using an integer linear programming optimization formulation on phosphoproteomic data A Mitsos, IN Melas, P Siminelakis, AD Chairakaki, J Saez-Rodriguez, ... PLoS computational biology 5 (12), e1000591, 2009 | 144 | 2009 |
| Synergistic drug–cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity BD Cosgrove, BM King, MA Hasan, LG Alexopoulos, PA Farazi, ... Toxicology and applied pharmacology 237 (3), 317-330, 2009 | 134 | 2009 |
| Networks inferred from biochemical data reveal profound differences in toll-like receptor and inflammatory signaling between normal and transformed hepatocytes LG Alexopoulos, J Saez-Rodriguez, BD Cosgrove, DA Lauffenburger, ... Molecular & Cellular Proteomics 9 (9), 1849-1865, 2010 | 124 | 2010 |
| Zonal uniformity in mechanical properties of the chondrocyte pericellular matrix: micropipette aspiration of canine chondrons isolated by cartilage homogenization F Guilak, LG Alexopoulos, MA Haider, HP Ting-Beall, LA Setton Annals of biomedical engineering 33 (10), 1312-1318, 2005 | 121 | 2005 |
| Verification of systems biology research in the age of collaborative competition P Meyer, LG Alexopoulos, T Bonk, A Califano, CR Cho, A De La Fuente, ... Nature biotechnology 29 (9), 811-815, 2011 | 92 | 2011 |
| A deep learning framework for predicting response to therapy in cancer T Sakellaropoulos, K Vougas, S Narang, F Koinis, A Kotsinas, A Polyzos, ... Cell reports 29 (11), 3367-3373. e4, 2019 | 88 | 2019 |
| Flexible informatics for linking experimental data to mathematical models via DataRail J Saez-Rodriguez, A Goldsipe, J Muhlich, LG Alexopoulos, B Millard, ... Bioinformatics 24 (6), 840-847, 2008 | 86 | 2008 |
Julio Saez RodriguezHeidelberg UniversityDirección de correo verificada de bioquant.uni-heidelberg.de
