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Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients
M Pirmohamed, S James, S Meakin, C Green, AK Scott, TJ Walley, ...
Bmj 329 (7456), 15-19, 2004
46452004
Drug repurposing: progress, challenges and recommendations
S Pushpakom, F Iorio, PA Eyers, KJ Escott, S Hopper, A Wells, A Doig, ...
Nature reviews Drug discovery 18 (1), 41-58, 2019
38682019
Estimation of the warfarin dose with clinical and pharmacogenetic data
International Warfarin Pharmacogenetics Consortium
New England Journal of Medicine 360 (8), 753-764, 2009
18632009
Phase I clinical trial of oral curcumin: biomarkers of systemic activity and compliance
RA Sharma, SA Euden, SL Platton, DN Cooke, A Shafayat, HR Hewitt, ...
Clinical cancer research 10 (20), 6847-6854, 2004
16052004
HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin
AK Daly, PT Donaldson, P Bhatnagar, Y Shen, I Pe'er, A Floratos, MJ Daly, ...
Nature genetics 41 (7), 816-819, 2009
11952009
Pharmacodynamic and Pharmacokinetic Study of Oral Curcuma Extract in Patients with Colorectal Cancer
RA Sharma, HR McLelland, KA Hill, CR Ireson, SA Euden, MM Manson, ...
Clinical Cancer Research 7 (7), 1894-1900, 2001
11282001
HLA-A* 3101 and carbamazepine-induced hypersensitivity reactions in Europeans
M McCormack, A Alfirevic, S Bourgeois, JJ Farrell, D Kasperavičiūtė, ...
New England Journal of Medicine 364 (12), 1134-1143, 2011
11112011
Adverse drug reactions in hospital in-patients: a prospective analysis of 3695 patient-episodes
EC Davies, CF Green, S Taylor, PR Williamson, DR Mottram, ...
PLoS one 4 (2), e4439, 2009
10042009
A randomized trial of genotype-guided dosing of warfarin
M Pirmohamed, G Burnside, N Eriksson, AL Jorgensen, CH Toh, ...
New England Journal of Medicine 369 (24), 2294-2303, 2013
9732013
Adverse drug reactions
M Pirmohamed, AM Breckenridge, NR Kitteringham, BK Park
Bmj 316 (7140), 1295-1298, 1998
857*1998
Emergence and global spread of epidemic healthcare-associated Clostridium difficile
M He, F Miyajima, P Roberts, L Ellison, DJ Pickard, MJ Martin, TR Connor, ...
Nature genetics 45 (1), 109-113, 2013
8392013
Which drugs cause preventable admissions to hospital? A systematic review
RL Howard, AJ Avery, S Slavenburg, S Royal, G Pipe, P Lucassen, ...
British journal of clinical pharmacology 63 (2), 136-147, 2007
8192007
Active transport of imatinib into and out of cells: implications for drug resistance
J Thomas, L Wang, RE Clark, M Pirmohamed
Blood 104 (12), 3739-3745, 2004
8002004
Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 Genotypes and Warfarin Dosing
JA Johnson, L Gong, M Whirl‐Carrillo, BF Gage, SA Scott, CM Stein, ...
Clinical Pharmacology & Therapeutics 90 (4), 625-629, 2011
7752011
Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for pharmacogenetics‐guided warfarin dosing: 2017 update
JA Johnson, KE Caudle, L Gong, M Whirl‐Carrillo, CM Stein, SA Scott, ...
Clinical Pharmacology & Therapeutics 102 (3), 397-404, 2017
6452017
The role of metabolic activation in drug-induced hepatotoxicity
BK Park, NR Kitteringham, JL Maggs, M Pirmohamed, DP Williams
Annu. Rev. Pharmacol. Toxicol. 45 (1), 177-202, 2005
6002005
Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology
T Eschenhagen, T Force, MS Ewer, GW De Keulenaer, TM Suter, ...
European journal of heart failure 13 (1), 1-10, 2011
5152011
Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles
MI Lucena, M Molokhia, Y Shen, TJ Urban, GP Aithal, RJ Andrade, ...
Gastroenterology 141 (1), 338-347, 2011
5102011
Pharmacogenetics of warfarin: current status and future challenges
M Wadelius, M Pirmohamed
The pharmacogenomics journal 7 (2), 99-111, 2007
4472007
Genetic susceptibility to adverse drug reactions
M Pirmohamed, BK Park
Trends in pharmacological sciences 22 (6), 298-305, 2001
4212001
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