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Sara Wells
Sara Wells
Director, Medical Research Council
Dirección de correo verificada de har.mrc.ac.uk - Página principal
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High-throughput discovery of novel developmental phenotypes
ME Dickinson, AM Flenniken, X Ji, L Teboul, MD Wong, JK White, ...
Nature 537 (7621), 508-514, 2016
10842016
Overexpression of Fto leads to increased food intake and results in obesity
C Church, L Moir, F McMurray, C Girard, GT Banks, L Teboul, S Wells, ...
Nature genetics 42 (12), 1086-1092, 2010
8532010
A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains
MM Simon, S Greenaway, JK White, H Fuchs, V Gailus-Durner, S Wells, ...
Genome biology 14, 1-22, 2013
5282013
Prevalence of sexual dimorphism in mammalian phenotypic traits
NA Karp, J Mason, AL Beaudet, Y Benjamini, L Bower, RE Braun, ...
Nature communications 8 (1), 15475, 2017
2432017
Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium
TF Meehan, N Conte, DB West, JO Jacobsen, J Mason, J Warren, ...
Nature genetics 49 (8), 1231-1238, 2017
2312017
ENU mutagenesis, a way forward to understand gene function
A Acevedo-Arozena, S Wells, P Potter, M Kelly, RD Cox, SDM Brown
Annu. Rev. Genomics Hum. Genet. 9 (1), 49-69, 2008
2252008
A guide to defining and implementing protocols for the welfare assessment of laboratory animals: eleventh report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement
P Hawkins, DB Morton, O Burman, N Dennison, P Honess, M Jennings, ...
Laboratory Animals 45 (1), 1-13, 2011
1912011
The fantasy of authenticity: Touring with Lacan
DC Knudsen, JM Rickly, ES Vidon
Annals of Tourism Research 58, 33-45, 2016
1852016
A Mutation in the Mitochondrial Fission Gene Dnm1l Leads to Cardiomyopathy
H Ashrafian, L Docherty, V Leo, C Towlson, M Neilan, V Steeples, ...
Plos genetics 6 (6), e1001000, 2010
1822010
A gene-driven ENU-based approach to generating an allelic series in any gene
MM Quwailid, A Hugill, N Dear, L Vizor, S Wells, E Horner, S Fuller, ...
Mammalian Genome 15, 585-591, 2004
1792004
Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination
D Bogani, P Siggers, R Brixey, N Warr, S Beddow, J Edwards, D Williams, ...
PLoS biology 7 (9), e1000196, 2009
1742009
Adult Onset Global Loss of the Fto Gene Alters Body Composition and Metabolism in the Mouse
F McMurray, CD Church, R Larder, G Nicholson, S Wells, L Teboul, ...
PLoS genetics 9 (1), e1003166, 2013
1712013
Assessing mouse behaviour throughout the light/dark cycle using automated in-cage analysis tools
RS Bains, S Wells, RR Sillito, JD Armstrong, HL Cater, G Banks, ...
Journal of neuroscience methods 300, 37-47, 2018
1622018
Dominant β-catenin mutations cause intellectual disability with recognizable syndromic features
V Tucci, T Kleefstra, A Hardy, I Heise, S Maggi, MH Willemsen, H Hilton, ...
The Journal of clinical investigation 124 (4), 1468-1482, 2014
1602014
Gadd45γ and Map3k4 interactions regulate mouse testis determination via p38 MAPK-mediated control of Sry expression
N Warr, GA Carre, P Siggers, JV Faleato, R Brixey, M Pope, D Bogani, ...
Developmental cell 23 (5), 1020-1031, 2012
1552012
Mouse large-scale phenotyping initiatives: Overview of the European mouse disease clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project
A Ayadi, MC Birling, J Bottomley, J Bussell, H Fuchs, M Fray, ...
Mammalian Genome 23, 600-610, 2012
1542012
The International Mouse Phenotyping Consortium: comprehensive knockout phenotyping underpinning the study of human disease
T Groza, FL Gomez, HH Mashhadi, V Muñoz-Fuentes, O Gunes, R Wilson, ...
Nucleic acids research 51 (D1), D1038-D1045, 2023
1532023
Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics
M Hrabě de Angelis, G Nicholson, M Selloum, JK White, H Morgan, ...
Nature genetics 47 (9), 969-978, 2015
1472015
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction
MR Bowl, MM Simon, NJ Ingham, S Greenaway, L Santos, H Cater, ...
Nature communications 8 (1), 886, 2017
1372017
Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing
J Nicod, RW Davies, N Cai, C Hassett, L Goodstadt, C Cosgrove, BK Yee, ...
Nature genetics 48 (8), 912-918, 2016
1362016
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20