| Cells navigate with a local-excitation, global-inhibition-biased excitable network Y Xiong, CH Huang, PA Iglesias, PN Devreotes Proceedings of the National Academy of Sciences 107 (40), 17079-17086, 2010 | 299 | 2010 |
| PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis L Chen, M Iijima, M Tang, MA Landree, YE Huang, Y Xiong, PA Iglesias, ... Developmental cell 12 (4), 603-614, 2007 | 242 | 2007 |
| PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis Y Kamimura, Y Xiong, PA Iglesias, O Hoeller, P Bolourani, PN Devreotes Current Biology 18 (14), 1034-1043, 2008 | 219 | 2008 |
| Lineage mapping the pre-implantation mouse embryo by two-photon microscopy, new insights into the segregation of cell fates K McDole, Y Xiong, PA Iglesias, Y Zheng Developmental biology 355 (2), 239-249, 2011 | 91 | 2011 |
| A novel white blood cell segmentation scheme based on feature space clustering K Jiang, QM Liao, Y Xiong Soft Computing 10, 12-19, 2006 | 76 | 2006 |
| Ceftazidime‐avibactam population pharmacokinetic modeling and pharmacodynamic target attainment across adult indications and patient subgroups J Li, M Lovern, ML Green, J Chiu, D Zhou, C Comisar, Y Xiong, J Hing, ... Clinical and Translational Science 12 (2), 151-163, 2019 | 74 | 2019 |
| A model-based approach to investigating the pathophysiological mechanisms of hypertension and response to antihypertensive therapies: extending the Guyton model H KM, L A, B J, R M, E S, F S, de Leon H, S A, X Y, S R, S H, W R, K AG American Journal of Physiology - Regulatory, Integrative and Comparative …, 2014 | 69 | 2014 |
| Nonlinear mixed‐effects model development and simulation using nlmixr and related R open‐source packages M Fidler, JJ Wilkins, R Hooijmaijers, TM Post, R Schoemaker, MN Trame, ... CPT: pharmacometrics & systems pharmacology 8 (9), 621-633, 2019 | 52 | 2019 |
| Automated characterization of cell shape changes during amoeboid motility by skeletonization Y Xiong, C Kabacoff, J Franca-Koh, PN Devreotes, DN Robinson, ... BMC systems biology 4, 1-18, 2010 | 45 | 2010 |
| tsunami, the Dictyostelium homolog of the Fused kinase, is required for polarization and chemotaxis L Tang, J Franca-Koh, Y Xiong, MY Chen, Y Long, RM Bickford, ... Genes & development 22 (16), 2278-2290, 2008 | 35 | 2008 |
| Tools for analyzing cell shape changes during chemotaxis Y Xiong, PA Iglesias Integrative Biology 2 (11-12), 561-567, 2010 | 32 | 2010 |
| Population pharmacokinetics of cabotegravir following administration of oral tablet and long‐acting intramuscular injection in adult HIV‐1‐infected and uninfected subjects K Han, M Baker, M Lovern, P Paul, Y Xiong, P Patel, KP Moore, CS Seal, ... British Journal of Clinical Pharmacology 88 (10), 4607-4622, 2022 | 28 | 2022 |
| Population pharmacokinetics of trastuzumab deruxtecan in patients with HER2‐positive breast cancer and other solid tumors O Yin, Y Xiong, S Endo, K Yoshihara, T Garimella, M AbuTarif, R Wada, ... Clinical Pharmacology & Therapeutics 109 (5), 1314-1325, 2021 | 27 | 2021 |
| Dynacortin facilitates polarization of chemotaxing cells C Kabacoff, Y Xiong, R Musib, EM Reichl, J Kim, PA Iglesias, ... BMC biology 5, 1-15, 2007 | 17 | 2007 |
| Effects of renal impairment on steady-state plasma concentrations of rivastigmine: a population pharmacokinetic analysis of capsule and patch formulations in patients with … G Lefevre, F Callegari, S Gsteiger, Y Xiong Drugs & aging 33, 725-736, 2016 | 13 | 2016 |
| Model‐informed drug repurposing: a pharmacometric approach to novel pathogen preparedness, response and retrospection M Dodds, Y Xiong, S Mouksassi, CM Kirkpatrick, K Hui, E Doyle, K Patel, ... British journal of clinical pharmacology 87 (9), 3388-3397, 2021 | 12 | 2021 |
| nlmixr: Nonlinear mixed effects models in population pharmacokinetics and pharmacodynamics M Fidler, Y Xiong, R Schoemaker, J Wilkins, M Trame, T Post, W Wang R package version 2 (1), 2021 | 11 | 2021 |
| Performance of the SAEM and FOCEI algorithms in the open‐source, nonlinear mixed effect modeling tool nlmixr R Schoemaker, M Fidler, C Laveille, JJ Wilkins, R Hooijmaijers, TM Post, ... CPT: Pharmacometrics & Systems Pharmacology 8 (12), 923-930, 2019 | 9 | 2019 |
| Population pharmacokinetics and exposure‐response modeling of daratumumab subcutaneous administration in patients with light‐chain amyloidosis M Luo, P Zhu, I Nnane, Y Xiong, G Merlini, RL Comenzo, E Kastritis, ... The Journal of Clinical Pharmacology 62 (5), 656-669, 2022 | 6 | 2022 |
| R and nlmixr as a gateway between statistics and pharmacometrics M Fidler, R Hooijmaijers, R Schoemaker, JJ Wilkins, Y Xiong, W Wang CPT: Pharmacometrics & Systems Pharmacology 10 (4), 283, 2021 | 6 | 2021 |
Pablo A. IglesiasEdward J. Schaefer Professor of Electrical Engineering, The Johns Hopkins UniversityVerified email at jhu.edu
