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Millard H Lambert
Millard H Lambert
Computational Chemist, GlaxoSmithKline
Dirección de correo verificada de gsk.com
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Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ
RT Nolte, GB Wisely, S Westin, JE Cobb, MH Lambert, R Kurokawa, ...
Nature 395 (6698), 137-143, 1998
23261998
Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α
ML Moss, SLC Jin, ME Milla, W Burkhart, HL Carter, WJ Chen, WC Clay, ...
Nature 385 (6618), 733-736, 1997
20371997
Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α
ML Moss, SLC Jin, ME Milla, W Burkhart, HL Carter, WJ Chen, WC Clay, ...
Nature 385 (6618), 733-736, 1997
20371997
A critical assessment of docking programs and scoring functions
GL Warren, CW Andrews, AM Capelli, B Clarke, J LaLonde, MH Lambert, ...
Journal of medicinal chemistry 49 (20), 5912-5931, 2006
17542006
A critical assessment of docking programs and scoring functions
GL Warren, CW Andrews, AM Capelli, B Clarke, J LaLonde, MH Lambert, ...
Journal of medicinal chemistry 49 (20), 5912-5931, 2006
17542006
Molecular recognition of fatty acids by peroxisome proliferator–activated receptors
HE Xu, MH Lambert, VG Montana, DJ Parks, SG Blanchard, PJ Brown, ...
Molecular cell 3 (3), 397-403, 1999
14211999
A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport
WR Oliver Jr, JL Shenk, MR Snaith, CS Russell, KD Plunket, NL Bodkin, ...
Proceedings of the national academy of sciences 98 (9), 5306-5311, 2001
13872001
Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition
RK Bledsoe, VG Montana, TB Stanley, CJ Delves, CJ Apolito, DD McKee, ...
Cell 110 (1), 93-105, 2002
9112002
The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity
RE Watkins, GB Wisely, LB Moore, JL Collins, MH Lambert, SP Williams, ...
Science 292 (5525), 2329-2333, 2001
8972001
The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution
SA Jones, LB Moore, JL Shenk, GB Wisely, GA Hamilton, DD McKee, ...
Molecular endocrinology 14 (1), 27-39, 2000
8272000
Peroxisome proliferator-activated receptor (gamma) and metabolic disease
TM Willson, MH Lambert, SA Kliewer
Annual review of biochemistry 70, 341, 2001
7672001
Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα
HE Xu, TB Stanley, VG Montana, MH Lambert, BG Shearer, JE Cobb, ...
Nature 415 (6873), 813-817, 2002
7112002
Asymmetry in the PPARγ/RXRα crystal structure reveals the molecular basis of heterodimerization among nuclear receptors
RT Gampe Jr, VG Montana, MH Lambert, AB Miller, RK Bledsoe, ...
Molecular cell 5 (3), 545-555, 2000
6972000
Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors
HE Xu, MH Lambert, VG Montana, KD Plunket, LB Moore, JL Collins, ...
Proceedings of the National Academy of Sciences 98 (24), 13919-13924, 2001
6392001
Molecular determinants of nuclear receptor–corepressor interaction
V Perissi, LM Staszewski, EM McInerney, R Kurokawa, A Krones, ...
Genes & development 13 (24), 3198-3208, 1999
6011999
Peroxisome proliferator-activated receptors: from genes to physiology.
SA Kliewer, HE Xu, MH Lambert, TM Willson
Recent progress in hormone research 56, 239-263, 2001
5322001
Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes
JM Maglich, DJ Parks, LB Moore, JL Collins, B Goodwin, AN Billin, ...
Journal of Biological Chemistry 278 (19), 17277-17283, 2003
4882003
Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors
LB Moore, JM Maglich, DD McKee, B Wisely, TM Willson, SA Kliewer, ...
Molecular endocrinology 16 (5), 977-986, 2002
4322002
Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity
RX Xu, AM Hassell, D Vanderwall, MH Lambert, WD Holmes, MA Luther, ...
Science 288 (5472), 1822-1825, 2000
4152000
Structure of the catalytic domain of fibroblast collagenase complexed with an inhibitor
B Lovejoy, A Cleasby, AM Hassell, K Longley, MA Luther, D Weigl, ...
Science 263 (5145), 375-377, 1994
3971994
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