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Wenming Xiao
Wenming Xiao
Office of Oncologic Diseases, CDER/FDA
Dirección de correo verificada de fda.hhs.gov
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Stromal gene signatures in large-B-cell lymphomas
G Lenz, G Wright, SS Dave, W Xiao, J Powell, H Zhao, W Xu, B Tan, ...
New England Journal of Medicine 359 (22), 2313-2323, 2008
19662008
Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma
RE Davis, VN Ngo, G Lenz, P Tolar, RM Young, PB Romesser, ...
Nature 463 (7277), 88-92, 2010
18802010
Genetics and pathogenesis of diffuse large B-cell lymphoma
R Schmitz, GW Wright, DW Huang, CA Johnson, JD Phelan, JQ Wang, ...
New England journal of medicine 378 (15), 1396-1407, 2018
17942018
Oncogenically active MYD88 mutations in human lymphoma
VN Ngo, RM Young, R Schmitz, S Jhavar, W Xiao, KH Lim, ...
Nature 470 (7332), 115-119, 2011
17222011
Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways
G Lenz, GW Wright, NCT Emre, H Kohlhammer, SS Dave, RE Davis, ...
Proceedings of the National Academy of Sciences 105 (36), 13520-13525, 2008
11562008
Frequent engagement of the classical and alternative NF-κB pathways by diverse genetic abnormalities in multiple myeloma
CM Annunziata, RE Davis, Y Demchenko, W Bellamy, A Gabrea, F Zhan, ...
Cancer cell 12 (2), 115-130, 2007
11382007
Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
R Schmitz, RM Young, M Ceribelli, S Jhavar, W Xiao, M Zhang, G Wright, ...
Nature 490 (7418), 116-120, 2012
9702012
IRF4 addiction in multiple myeloma
AL Shaffer, NCT Emre, L Lamy, VN Ngo, G Wright, W Xiao, J Powell, ...
Nature 454 (7201), 226-231, 2008
7522008
Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma
Y Yang, AL Shaffer, NCT Emre, M Ceribelli, M Zhang, G Wright, W Xiao, ...
Cancer cell 21 (6), 723-737, 2012
5842012
Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells
C Kücük, B Jiang, X Hu, W Zhang, JKC Chan, W Xiao, N Lack, C Alkan, ...
Nature communications 6 (1), 6025, 2015
4042015
Large scale real-time PCR validation on gene expression measurements from two commercial long-oligonucleotide microarrays
Y Wang, C Barbacioru, F Hyland, W Xiao, KL Hunkapiller, J Blake, F Chan, ...
BMC genomics 7, 1-16, 2006
3652006
Cooperative epigenetic modulation by cancer amplicon genes
L Rui, NCT Emre, MJ Kruhlak, HJ Chung, C Steidl, G Slack, GW Wright, ...
Cancer cell 18 (6), 590-605, 2010
3172010
Loss of signalling via Gα13 in germinal centre B-cell-derived lymphoma
JR Muppidi, R Schmitz, JA Green, W Xiao, AB Larsen, SE Braun, J An, ...
Nature 516 (7530), 254-258, 2014
3072014
Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors
M Ceribelli, PN Kelly, AL Shaffer, GW Wright, W Xiao, Y Yang, ...
Proceedings of the National Academy of Sciences 111 (31), 11365-11370, 2014
2222014
Congenital B cell lymphocytosis explained by novel germline CARD11 mutations
AL Snow, W Xiao, JR Stinson, W Lu, B Chaigne-Delalande, L Zheng, ...
Journal of Experimental Medicine 209 (12), 2247-2261, 2012
1972012
Survival of human lymphoma cells requires B-cell receptor engagement by self-antigens
RM Young, T Wu, R Schmitz, M Dawood, W Xiao, JD Phelan, W Xu, ...
Proceedings of the National Academy of Sciences 112 (44), 13447-13454, 2015
1812015
Essential role of the linear ubiquitin chain assembly complex in lymphoma revealed by rare germline polymorphisms
Y Yang, R Schmitz, J Mitala, A Whiting, W Xiao, M Ceribelli, GW Wright, ...
Cancer discovery 4 (4), 480-493, 2014
1742014
Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling
EM Hartmann, E Campo, G Wright, G Lenz, I Salaverria, P Jares, W Xiao, ...
Blood, The Journal of the American Society of Hematology 116 (6), 953-961, 2010
1532010
A druggable TCF4-and BRD4-dependent transcriptional network sustains malignancy in blastic plasmacytoid dendritic cell neoplasm
M Ceribelli, ZE Hou, PN Kelly, G Wright, K Ganapathi, MO Evbuomwan, ...
Cancer cell 30 (5), 764-778, 2016
1462016
Gain-of-function CCR4 mutations in adult T cell leukemia/lymphoma
M Nakagawa, R Schmitz, W Xiao, CK Goldman, W Xu, Y Yang, X Yu, ...
Journal of Experimental Medicine 211 (13), 2497-2505, 2014
1432014
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Artículos 1–20