Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/β-secretase expression SS Hébert, K Horré, L Nicolaï, AS Papadopoulou, W Mandemakers, ... Proceedings of the National Academy of Sciences 105 (17), 6415-6420, 2008 | 1371 | 2008 |
Alterations of the microRNA network cause neurodegenerative disease SS Hébert, B De Strooper Trends in neurosciences 32 (4), 199-206, 2009 | 517 | 2009 |
Phosphorylation of the translation initiation factor eIF2α increases BACE1 levels and promotes amyloidogenesis T O'Connor, KR Sadleir, E Maus, RA Velliquette, J Zhao, SL Cole, ... Neuron 60 (6), 988-1009, 2008 | 498 | 2008 |
MicroRNA regulation of Alzheimer's Amyloid precursor protein expression SS Hébert, K Horré, L Nicolaï, B Bergmans, AS Papadopoulou, ... Neurobiology of disease 33 (3), 422-428, 2009 | 488 | 2009 |
Loss‐of‐function presenilin mutations in Alzheimer disease: Talking Point on the role of presenilin mutations in Alzheimer disease B De Strooper EMBO reports 8 (2), 141-146, 2007 | 475 | 2007 |
The miR-15/107 group of microRNA genes: evolutionary biology, cellular functions, and roles in human diseases JR Finnerty, WX Wang, SS Hébert, BR Wilfred, G Mao, PT Nelson Journal of molecular biology 402 (3), 491-509, 2010 | 415 | 2010 |
The amyloid‐β precursor protein: integrating structure with biological function C Reinhard, SS Hébert, B De Strooper The EMBO journal 24 (23), 3996-4006, 2005 | 389 | 2005 |
Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration SS Hébert, AS Papadopoulou, P Smith, MC Galas, E Planel, ... Human molecular genetics 19 (20), 3959-3969, 2010 | 354 | 2010 |
In vivo regulation of amyloid precursor protein neuronal splicing by microRNAs P Smith, A Al Hashimi, J Girard, C Delay, SS Hébert Journal of neurochemistry 116 (2), 240-247, 2011 | 252 | 2011 |
Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes SS Hébert, L Serneels, A Tolia, K Craessaerts, C Derks, MA Filippov, ... EMBO reports 7 (7), 739-745, 2006 | 248 | 2006 |
Differential contribution of the three Aph1 genes to γ-secretase activity in vivo L Serneels, T Dejaegere, K Craessaerts, K Horré, E Jorissen, T Tousseyn, ... Proceedings of the National Academy of Sciences 102 (5), 1719-1724, 2005 | 244 | 2005 |
MicroRNAs in Alzheimer's disease C Delay, W Mandemakers, SS Hébert Neurobiology of disease 46 (2), 285-290, 2012 | 243 | 2012 |
Amyloid precursor protein promotes post‐developmental neurite arborization in the Drosophila brain M Leyssen, D Ayaz, SS Hébert, S Reeve, B De Strooper, BA Hassan The EMBO journal 24 (16), 2944-2955, 2005 | 243 | 2005 |
miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo PY Smith, J Hernandez-Rapp, F Jolivette, C Lecours, K Bisht, C Goupil, ... Human molecular genetics 24 (23), 6721-6735, 2015 | 228 | 2015 |
Coordinated and widespread expression of γ-secretase in vivo: evidence for size and molecular heterogeneity SS Hébert, L Serneels, T Dejaegere, K Horré, M Dabrowski, V Baert, ... Neurobiology of disease 17 (2), 260-272, 2004 | 202 | 2004 |
miRNAs in neurodegeneration SS Hébert, B De Strooper Science 317 (5842), 1179-1180, 2007 | 196 | 2007 |
A novel microRNA-124/PTPN1 signal pathway mediates synaptic and memory deficits in Alzheimer’s disease X Wang, D Liu, HZ Huang, ZH Wang, TY Hou, X Yang, P Pang, N Wei, ... Biological psychiatry 83 (5), 395-405, 2018 | 187 | 2018 |
Alzheimer-specific variants in the 3'UTR of Amyloid precursor protein affect microRNA function C Delay, F Calon, P Mathews, SS Hébert Molecular neurodegeneration 6, 1-6, 2011 | 179 | 2011 |
MicroRNA-132 loss is associated with tau exon 10 inclusion in progressive supranuclear palsy PY Smith, C Delay, J Girard, MA Papon, E Planel, N Sergeant, L Buée, ... Human molecular genetics 20 (20), 4016-4024, 2011 | 177 | 2011 |
Prenatal immune challenge in mice leads to partly sex-dependent behavioral, microglial, and molecular abnormalities associated with schizophrenia CW Hui, A St-Pierre, H El Hajj, Y Remy, SS Hébert, GN Luheshi, ... Frontiers in molecular neuroscience 11, 13, 2018 | 146 | 2018 |