Tailoring adipose stem cell trophic factor production with differentiation medium components to regenerate chondral defects CSD Lee, E Watkins, OA Burnsed, Z Schwartz, BD Boyan Tissue Engineering Part A 19 (11-12), 1451-1464, 2013 | 40 | 2013 |
Engineered bridge protein with dual affinity for bone morphogenetic protein-2 and collagen enhances bone regeneration for spinal fusion PS Briquez, HM Tsai, EA Watkins, JA Hubbell Science Advances 7 (24), eabh4302, 2021 | 30 | 2021 |
Prolonged residence of an albumin–IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis A Ishihara, J Ishihara, EA Watkins, AC Tremain, M Nguyen, A Solanki, ... Nature Biomedical Engineering 5 (5), 387-398, 2021 | 29 | 2021 |
Polymersomes decorated with the SARS-CoV-2 spike protein receptor-binding domain elicit robust humoral and cellular immunity LR Volpatti, RP Wallace, S Cao, MM Raczy, R Wang, LT Gray, AT Alpar, ... ACS central science 7 (8), 1368-1380, 2021 | 28 | 2021 |
Generation of potent cellular and humoral immunity against SARS-CoV-2 antigens via conjugation to a polymeric glyco-adjuvant LT Gray, MM Raczy, PS Briquez, TM Marchell, AT Alpar, RP Wallace, ... Biomaterials 278, 121159, 2021 | 22 | 2021 |
Suppression of rheumatoid arthritis by enhanced lymph node trafficking of engineered interleukin‐10 in murine models E Yuba, E Budina, K Katsumata, A Ishihara, A Mansurov, AT Alpar, ... Arthritis & Rheumatology 73 (5), 769-778, 2021 | 20 | 2021 |
Synthetically glycosylated antigens for the antigen-specific suppression of established immune responses AC Tremain, RP Wallace, KM Lorentz, TB Thornley, JT Antane, MR Raczy, ... Nature Biomedical Engineering 7 (9), 1142-1155, 2023 | 16 | 2023 |
Resilience of T cell-intrinsic dysfunction in transplantation tolerance ML Miller, CM McIntosh, Y Wang, L Chen, P Wang, YM Lei, MD Daniels, ... Proceedings of the National Academy of Sciences 116 (47), 23682-23690, 2019 | 16 | 2019 |
Persistent antigen exposure via the eryptotic pathway drives terminal T cell dysfunction EA Watkins, JT Antane, JL Roberts, KM Lorentz, S Zuerndorfer, AC Dunaif, ... Science Immunology 6 (56), eabe1801, 2021 | 15 | 2021 |
Adipose stem cell microbeads as production sources for chondrogenic growth factors CSD Lee, AM Nicolini, EA Watkins, OA Burnsed, BD Boyan, Z Schwartz Journal of Stem Cells & Regenerative Medicine 10 (2), 38, 2014 | 12 | 2014 |
Soluble N-acetylgalactosamine-modified antigens enhance hepatocyte-dependent antigen cross-presentation and result in antigen-specific CD8+ T cell tolerance development M Damo, DS Wilson, EA Watkins, JA Hubbell Frontiers in Immunology 12, 555095, 2021 | 11 | 2021 |
Lymph node-targeted synthetically glycosylated antigen leads to antigen-specific immunological tolerance CD Maulloo, S Cao, EA Watkins, MM Raczy, AS Solanki, M Nguyen, ... Frontiers in Immunology, 3920, 2021 | 10 | 2021 |
Designing biofunctional immunotherapies EA Watkins, JA Hubbell Nature Reviews Materials 4 (6), 350-352, 2019 | 6 | 2019 |
Targeted polymersome delivery of a stapled peptide for drugging the tumor protein p53: BCL-2-family axis in diffuse large B-cell lymphoma MR Schnorenberg, KM Hawley, AT Thomas-Toth, EA Watkins, Y Tian, ... ACS nano 17 (23), 23374-23390, 2023 | 4 | 2023 |
Seryl-butyrate: a prodrug that enhances butyrate's oral bioavailability and suppresses autoimmune arthritis and experimental autoimmune encephalomyelitis S Cao, E Budina, MM Raczy, A Solanki, M Nguyen, K Hultgren, P Ang, ... | 2 | 2023 |
Prolonged residence of an albumin-IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis (Oct, 10.1038/s41551-020-00627-3, 2020) A Ishihara, J Ishihara, EA Watkins, AC Tremain, M Nguyen, A Solanki, ... NATURE BIOMEDICAL ENGINEERING 4 (11), 1117-1117, 2020 | 2 | 2020 |
Synthetically mannosylated antigens induce antigen-specific humoral tolerance and reduce anti-drug antibody responses to immunogenic biologics RP Wallace, KC Refvik, JT Antane, K Brünggel, AC Tremain, MR Raczy, ... Cell Reports Medicine 5 (1), 2024 | 1 | 2024 |
Mannose‐Decorated Co‐Polymer Facilitates Controlled Release of Butyrate to Accelerate Chronic Wound Healing AL Lauterbach, AJ Slezak, R Wang, S Cao, MM Raczy, EA Watkins, ... Advanced Healthcare Materials 12 (26), 2300515, 2023 | 1 | 2023 |
A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice S Cao, E Budina, MM Raczy, A Solanki, M Nguyen, TN Beckman, ... Nature Biomedical Engineering, 1-17, 2024 | | 2024 |
Anti-inflammatory cytokines and methods of use JA Hubbell, Y Eiji, E Watkins, J Ishihara, A Ishihara, E Budina, ... US Patent App. 18/246,512, 2024 | | 2024 |